Systems biology is the study of the dynamic interactions of more
than one component in a biological system in order to understand
and predict the behavior of the system as a whole. Systems biology
is a rapidly expanding discipline fuelled by the 'omics' era and
new technological advances that have increased the precision of
data. A focus on simple single cell organisms, such as bacteria,
aids tractability and means that systems microbiology is a rapidly
maturing science. Recommended for all microbiology laboratories,
this book contains cutting-edge reviews by world-leading experts on
the systems biology of microorganisms. As well as covering
theoretical approaches and mathematical modeling, the book includes
case studies on single microbial species of bacteria and archaea,
and it explores the systems analysis of microbial phenomena, such
as chemotaxis and phagocytosis. The topics covered include: the
mathematical models for systems biology * systems biology of
Escherichia coli metabolism * bacterial chemotaxis * systems
biology of infection * host-microbe interactions * phagocytosis *
system-level study of metabolism in Mycobacterium tuberculosis *
systems biology of Sulfolobus.
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