As a medical detective of the modern world, forensic pathologist Ryan Blumenthal’s chief goal is to bring perpetrators to justice. He has performed thousands of autopsies, which have helped bring numerous criminals to book. In Autopsy he covers the hard lessons learnt as a rookie pathologist, as well as some of the most unusual cases he’s encountered.

During his career, for example, he has dealt with high-profile deaths, mass disasters, death by lightning and people killed by African wildlife. Blumenthal takes the reader behind the scenes at the mortuary, describing a typical autopsy and the instruments of the trade. He also shares a few trade secrets, like how to establish when a suicide is more likely to be a homicide.

Even though they cannot speak, the dead have a lot to say – and Blumenthal is there to listen.

Locard’s Exchange Principle underpins all forensic science and holds that the perpetrator of a crime will bring something to the crime scene and leave with something from it.

Forensic experts use this principle daily to catch murderers and assailants. In Risking Life for Death, South African forensic pathologist Ryan Blumenthal offers a master class in this singular forensic technique based on real-life case studies. With more than twenty years’ experience in the field, Blumenthal explains how to look for clues and traces, and how what he does not find at autopsy is often more important than what he does find. In other words, the absence of evidence can sometimes be of greater value than the presence of evidence.

His account also highlights the dangers forensic pathologists are exposed to daily. As they try to unravel the puzzle of someone’s death, forensic pathologists often face life-threatening infections, toxic gases and the hazards associated with high-profile cases – in effect, risking their life to solve someone else’s death.

An understanding of Locard’s Exchange Principle can help you become a medical detective in your own life, can help you be a happier person and can even provide you with a better philosophy for growing older, Blumenthal argues.

Lucy Easthope lives with disaster every day. When a plane crashes, a bomb explodes, a city floods or a pandemic begins, she's the one they call. As one of the world's leading experts on disaster she has been at the centre of the most seismic events of the last few decades - advising on everything from the 2004 Boxing Day tsunami to the 7/7 bombings, the Salisbury poisonings, the Grenfell fire and the Covid-19 pandemic.

She has travelled across the world in this unusual role, seeing the very worst that people have to face, and finding that even the most extreme of situations, we find the very best of humanity. In her moving memoir she reveals what happens in the aftermath. She takes us behind the police tape to scenes of destruction and chaos, introducing us to victims and their families, but also to the government briefing rooms and bunkers, where confusion and stale biscuits can reign supreme.

With wisdom, resilience and candour When the Dust Settles looks back at a life spent on the edges of disaster and shows us that where there is terrible tragedy there is also great hope and that humanity and humour can - and must - still be found on the darkest of days.

In endocrine pathology, surgical pathologists often concentrate on neoplasms at the expense of nonneoplastic disease processes. This is unfortunate as nonneoplastic endocrine disorders are many times more common in the population. As in all fields of medicine, nonneoplastic endocrine diseases can closely mimic the neoplastic; an awareness of all aspects of pathology underpins routine clinical practice. This Fifth Series Fascicle offers pathologists and clinicians an opportunity to develop an increased understanding of nontumor endocrine pathology in order to inform patient care.

**A NEW YORK TIMES BOOK OF THE YEAR 2022** From the author of Spillover, the book that predicted the pandemic, Breathless is the story of Covid-19 and its fierce journey through the human population, as seen by the scientists tasked with fighting it. Bestelling author David Quammen draws on countless interviews with experts, including leading virologists, to take us inside the global race to understand SARS-CoV-2, it's ever-changing nature and capacity to kill. In doing so, he explains how new viruses emerge when we disrupt ecosystems and suggests why the coronavirus may be here to stay. By peering over the shoulders of the brilliant scientists leading the chase, Breathless uncovers the warnings from infectious diseases experts that went unheeded; and which clues are the most compelling in the hunt for the virus' origin. 'A viral howdunnit that is pacy and unafraid to educate readers' Observer 'A luminous, passionate account of the defining crisis of our time' New York Times 'A classic...a masterpiece' Stanley Prusiner, Nobel Prize Winner 'As close to authoritative history as we have... It reads like a real-time thriller' Chicago Tribune

This volume discusses the oral microbiome, and oral and systemic health. The chapters in this book cover topics such as analytical techniques for identifying and measuring oral bacteria; strategies for controlling common sources of variability in oral microbiome methods for viral bacterial and fungal analysis; ways to study oral DNA and RNA samples to identify molecular pathways to disease; approaches to functional assays for oral bacteriophage, antibiotic purging of systemic bacteria; and metaproteomic analysis of various oral samples. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, The Oral Microbiome: Methods and Protocols is a valuable resource for any scientist or researcher looking to further study this exciting and developing field.

Since the publication of the 1/e in 1977, Blaustein's Pathology of the Female Genital Tract has consolidated its position as the leading textbook of gynecological pathology. An essential reference for all pathologists and residents, this thoroughly updated Seventh Edition includes more than 1400 illustrations in color, informative tables and 22 revised chapters written by internationally recognized experts. Discussion of each specific entity is organized to include general information, etiology, and epidemiology followed by clinical features, pathologic findings, differential diagnosis, clinical behavior, and treatment. This clear organization is applied throughout the book and allows the reader to quickly access key information in every chapter. Blaustein's Pathology of the Female Genital Tract remains the gold-standard reference for practicing pathologists and trainees, as well as for obstetric/gynecology practitioners and residents. Please find the index under "Back Matter" freely available on SpringerLink https://link.springer.com/referencework/10.1007%2F978-3-319-46334-6.

Key Features: • Discusses the clinical and applied aspects of forensic medicine through illustrative case scenarios and reports. • Addresses the needs of clinicians and forensic medicine specialists in writing medico-legal reports for specific cases. • Provides evidence-based solutions to medicolegal and ethical dilemma faced during routine practice.

This updated final volume in the best-selling series of reference works features descriptions of more than 200 genera in 49 families and includes a revised taxonomic outline for the Actinobacteria as well as many medically and industrially important taxa.

This book contains a compilation of high-yield, at-a-glance summaries in quick reference format for various topics that are frequently encountered by pathologists in the daily practice or on the boards. The focus is not organ-based histologic criteria, but rather everything else that goes into pathologic diagnoses but is difficult to keep committed to memory. The emphasis is on immunohistochemistry, special stains, grading systems, molecular markers, tumor syndromes, and helpful clinical references. Also included are morphologic summaries that encompass high-yield material cutting across all organ systems, such as an illustrated guide for microorganisms, tumor differentials, and an illustrated glossary of pathologic descriptors. The book has a unique format in that the information is presented primarily in tables and diagrams accompanied by brief and to-the-point explanatory text. The guiding principle was to boil the information down to the essentials but with just enough commentary to be accessible to a newcomer to pathology and to serve as a quick reference to a practicing pathologist.   In the 7 years since its initial publication, there have been considerable advances in surgical pathology, particularly immunohistochemical stains, molecular diagnostics, and histologic grading schemes.  In the second edition, the content has been thoroughly updated to incorporate these developments, while retaining the overall scope and concise format of the first edition. In addition, the reader will find summaries for many new topics as well as multiple new cartoon illustrations and diagrams. 

The heart-wrenchingly honest and fascinating new book from forensic pathologist and bestselling author of UNNATURAL CAUSES, Dr Richard Shepherd A TIMES AND SUNDAY TIMES BOOK OF THE YEAR 'Each chapter is like a finely-crafted detective story . . . Shepherd writes beautifully, and despite its subject, the book is very funny in parts' DAILY TELEGRAPH 'Enlightening, strangely uplifting . . . Shepherd's final chapter on death itself is a meditation of great beauty and light which puts all the darkness of the previous pages into perspective' DAILY MAIL 'Deeply insightful. Unflinching' THE TIMES 'Fascinating' DAILY EXPRESS 'This book is about death, but in it I will take readers on a journey through life . . .' _________ Dr Richard Shepherd, Britain's top forensic pathologist, has spent a lifetime close to the dead. As a medical detective, each autopsy he carries out is its own unique investigation, uncovering the secrets not only of how a person died, but also of how they lived. Through twenty-four of his most intriguing, enlightening and never-before-told cases, Dr Shepherd shares autopsies that span the seven ages of human existence, and have taught him as much about the marvels of life as the inevitability of death. From old to young, from murder to misadventure, and from illness to accidental death, each of these bodies has something to reveal: about human development, about mortality, about its owner's life story, about justice and even about Shepherd himself. From the bestselling author of Unnatural Causes comes a powerful, moving and above all reassuring book about death as it touches our own lives - how to understand it, and, when our time comes (as it must), how to embrace it as the last great adventure. _________ 'He has the ability to examine himself and other people with the same forensic eye that he applies to corpses - one of the reasons why his books feel so life-enhancing' Daily Telegraph Praise for Dr Richard Shepherd 'Gripping, grimly fascinating, and I suspect I'll read it at least twice' Evening Standard 'A deeply mesmerising memoir of forensic pathology. Human and fascinating' Nigella Lawson 'An absolutely brilliant book. I really recommend it, I don't often say that but it's fascinating' Jeremy Vine, BBC Radio 2 'Puts the reader at his elbow as he wields the scalpel' Guardian 'Fascinating, gruesome yet engrossing' Richard and Judy, Daily Express 'Fascinating, insightful, candid, compassionate' Observer

This book provides a practical guide for all those working in or with Medical Examiner Services in England and Wales. It is an adjunct to the e-learning and face-to-face training required to fulfil the Medical Examiner and Medical Examiner Officer roles. Medical Examiner Services also work closely with a wide range of stakeholders including bereavement and mortuary teams, Coroners and their Officers, Registrars, Funeral Directors and those working in clinical governance and patient safety. This book provides an essential overview of all aspects of the Medical Examiner system for anyone working in these areas, or in any aspect of the support and management of the deceased and bereaved. A concise guide including the knowledge base required to develop and run a Medical Examiner Service Content is completely aligned with required training Written by those with direct experience of establishing and working with Medical Examiner Services Relevant to a wide range of stakeholders who work with patients and the bereaved

The 10th edition of Porth's Pathophysiology: Concepts of Altered Health States continues a legacy of excellence by providing comprehensive, nursing-focused coverage designed to help grasp both the physical and psychological aspects of altered health. The book's unique emphasis on "concepts" of altered health states, as opposed to factual descriptions of diseases and disorders, helps students grasp both the physical and psychological aspects of altered health. The Tenth Edition maintains its comprehensive depth with over 1,100 illustrations to show students the complex pathophysiology. In addition, over 40 advanced 3D narrated animations that address the most clinically relevant and difficult to understand disorders, engaging unit-opening case studies that reinforce critical thinking and set the tone for the content to come, and a wide range of built-in study tools. Porth's Pathophysiology: Concepts of Altered Health States is designed to make pathophysiology an exciting exploration that relates normal body functioning to the physiologic changes that occur as a result of disease, as well as the body's remarkable ability to compensate for these changes. Indeed, it is these changes that represent the signs and symptoms of disease. Students develop a strong understanding of pathophysiology concepts with the easy-to-follow narrative that builds concepts on one another, defines words as content is presented, and reviews concepts from physiology, biochemistry, physics, and other sciences along the way. Key Features of 10E: *NEW* A new unit on Emergency Medicine . The new chapters in this section are: Bioterrorism, Emergency Psychological Issues, Burns, and Shock. The purpose of this unit is to introduce pathophysiology issues that appear in an Emergency Room or Emergency situation and are not covered elsewhere in the book. *NEW* Unfolding Patient Stories: This edition includes even more cases studies with the introduction of unfolding vSim vignettes called Unfolding Patient Stories. It is not necessary to have a vSim product to use this feature. These unfolding vignettes are designed to start conversations in the classroom by using vSim patients in the book. The vignettes are completely standalone cases but if a school is using vSim then student will be familiar with the patient. Unit opener Case Studies: Prepare for clinical practice with 14 unit-opening case studies that put a real face on pathophysiology and help you relate the clinical presentation to the underlying pathophysiology. Full-color Art: Increase your understanding of key concepts with the full-color art program comprised of over 1,100 illustrations showing the clinical manifestations of diseases and disease processes. Review exercises: Reinforce your understanding of key content with chapter-ending review exercises. Objectives and Summaries: Deepen your understanding by pausing and reviewing salient points using the easily-identified section-opening Objectives and section-ending Summaries . Key Concept Boxes: Retain and apply text information using the information in the boxes help you incorporate key information into a larger conceptual unit, rather than memorizing a string of related and unrelated facts. Lab References : Easily access useful references including lists of common suffixes and prefixes, normal laboratory values in both conventional and SI units, and a comprehensive glossary. Animations: Master the most clinically relevant and difficult to understand disorders with over 40 advanced 3D narrated animations.

THE SUNDAY TIMES BESTSELLER A RADIO 4 BOOK OF THE WEEK CHOSEN AS A BOOK OF THE YEAR BY THE TELEGRAPH AND THE NEW STATESMAN "A marvellous book" Rev Richard Coles "Gripping... filled with compassion." Sunday Times "Remarkable... hopeful and uplifting." Mail on Sunday "An antidote to despair" Daily Mirror "Enthralling... vivid and humane" Observer "Exemplary" New Statesman When a plane crashes, a bomb explodes, a city floods or a pandemic begins, Lucy Easthope's phone starts to ring. Lucy is a world-leading authority on recovering from disaster. She holds governments to account, supports survivors and helps communities to rebuild. She has been at the centre of the most seismic events of the last few decades, advising on everything from the 2004 tsunami and the 7/7 bombings to the Grenfell fire and the war in Ukraine. Lucy's job is to pick up the pieces and get us ready for what comes next. Lucy takes us behind the police tape to scenes of chaos, and into government briefing rooms where confusion can reign. She also looks back at the many losses and loves of her life and career, and tells us how we can all build back after disaster. When the Dust Settles lifts us up, showing that humanity, hope and humour can - and must - be found on the darkest days.

Key features: Succinct case studies presented in an easy-to-read format, listing patient history, examination and investigations Questions at the end of each case prompt readers to consider their options for diagnosis, investigation and management Answer pages then guide readers through the clinician's sequence of thoughts and actions Subsections include histopathology, laboratory medicine (chemical pathology and immunology), haematology and microbiology Illustrations, information boxes and key points summaries reinforce learning, ideal during exam revision A broad range of common conditions is covered, from acidosis to urinary tract infection, together with more unusual cases

Authored by the originator of the standard nomenclature for this spectrum of disorders, Congenital Heart Disease: A Clinical, Pathological, Embryological, and Segmental Analysis discusses the history, anatomic features, and physiologic consequences of CHD-in one authoritative resource. The Van Praagh approach to the segmental classification of CHD, developed and implemented by Dr. Richard Van Praagh in the 1960s at Boston Children's Hospital, remains widely used today, facilitating communication among radiologists, cardiologists, surgeons, and pediatricians who are involved in the diagnosis, characterization, and management of this disease. This unique atlas offers complete coverage of the ubiquitous Van Praagh "language" of CHD, including the signs, symptoms, and clinical manifestations of malpositioned, malformed, or absent cardiovascular chambers, vessels, and valves using traditional as well as state-of-the-art technology. Based upon the systematic, widely accepted Van Praagh system of three-part notation used to succinctly describe the visceroatrial situs, the orientation of the ventricular loop, and the position and relation of the great vessels. Demonstrates how the Van Praagh approach facilitates interpreting and reporting findings through cardiac imaging with CT, MR, and ultrasonography, including fetal cardiac imaging. Presents the pathologic anatomy that pediatric and adult cardiologists, radiologists, and echocardiographers need to understand in order to make accurate diagnoses in complex congenital heart disease; as well as the pathologic anatomy that interventionists, pediatric cardiac surgeons, and adult congenital heart surgeons need to know in order to manage their patients successfully. Features more than 550 high-quality images to help you visualize and recognize malformations. Shares the knowledge and expertise of a world-renowned authority on congenital heart disease-a master teacher and the originator of the Van Praagh segmental classification system. Explores the synergy between the various disciplines who manage patient care, including surgeons, radiologists, cardiologists, pathologists, and pediatricians. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Ground-breaking, evidence-based book asks how many lives were lost because of Chinas negligence about lab-leaked SARS-CoV-2. In a disturbing reconstruction of events by two of the most reputable scientists in the world, a new book reveals for the first time how Chinese authorities and elite Wuhan scientists knew about SARS-CoV-2s menacing biological features from the start but remain silent to this day. In The Origin of the Virus (Clinical Press) Dr Steven Quay and Prof Angus Dalgleish, working with Italian reporter Paolo Barnard, show how China engaged in lies, omissions and obfuscations to cover up the laboratory origin of the virus. Had they immediately alerted the international community and policymakers of the extremely pathogenic molecular machinery present in SARS-CoV-2's genome, very large numbers of lives may have been spared, argue Quay, Dalgleish and Barnard. The authors provide a shocking account of the extreme experiments that led to the outbreak of the worst pandemic since the 1918 Spanish influenza. They broaden the censure to explain why some American and British scientists thwarted a proper investigation of the origin of COVID-19. Despite its impeccable scientific grounding the book is both a readable and gripping account that, for the first time, allows the public to partake in what lies at the heart of the many scandals surrounding the birth of the most deadly virus in modern times.

Neurological Complications of Systematic Cancer and Antineoplastic Therapy, Second Edition provides an expanded, updated and in-depth review of common manifestations related to neurology that occur in patients with systemic cancer. These include brain metastases, spinal cord compression, cerebrovascular events, and leptomeningeal disease. The book also discusses neurological complications related to treatments such as radiation and chemotherapy and is an essential reference for the practicing neurologist and oncologist. Sections in this new release cover the pathophysiology and molecular biology of cancer and the metastatic phenotype, Metastatic spread to cranial and peripheral nerves and brachial and lumbosacral plexuses, Metabolic and nutritional disorders, CNS infections, Neurological complications of immunotherapy and bone marrow transplants, Neurological complications of new molecular agents and immuno-modulatory drugs, and more.

The much awaited third edition of the leading reference book in dermoscopy has undergone comprehensive revisions to all chapters, with updates and expanded content providing the reader with a more comprehensive and in-depth coverage of skin conditions, ranging from skin neoplasia to hair, nails, infections and inflammatory diseases. This compilation of contemporary dermoscopy knowledge will benefit the novice in building expertise and benefit experienced practitioners also by providing nuanced insights. Prepare to embark on a journey of learning as leading international experts in the field of dermoscopy explain via text and annotated exemplar images the amazing world of subsurface cutaneous colors and structures visible through a dermatoscope!

This cutting-edge monograph on advanced clinical anatomy and pathoanatomy of the shoulder, written by the world's leading authors, reflects recent significant advances in understanding of anatomy and pathology. It is beautifully illustrated with exquisite photographs of anatomical specimens, and images from arthroscopy, histology, and radiology complete the picture. The accompanying text brings out the clinical, biomechanical, and functional relevance and focuses on aspects important to the high-performance athlete. In addition, the book closely assesses how each component of the normal anatomy responds to trauma, disease, and degeneration. The finer points of the pathoanatomy are demonstrated with clinical cases, histology, radiology, arthroscopy, and open surgery. The text details how the pathoanatomy affects the patient presentation, clinical examination, and imaging. It is also explained how the pathology affects the natural history and the outcome of physical therapy and influences recommendations for surgical treatments. This book will be of immense value both to trainees and to specialists who manage disorders of the shoulder, including orthopedic surgeons, sports physicians, and physiotherapists. It will also be of great interest to anatomists and pathologists.

Key Features: • Discusses the clinical and applied aspects of forensic medicine through illustrative case scenarios and reports. • Addresses the needs of clinicians and forensic medicine specialists in writing medico-legal reports for specific cases. • Provides evidence-based solutions to medicolegal and ethical dilemma faced during routine practice.

This comprehensive volume includes chapters on bone growth and development, bone tumor imaging, molecular genetics, and all classes of bone and joint tumors. This Fascicle is designed for residents, fellows, and practicing physicians in fields that treat and study patients with bone tumors, including pathology, orthopedics, radiology, medical oncology, and radiation oncology. Along with a wide range of superb illustrations, the authors' discussions integrate their experience, recent molecular data, and updated information from the World Health Organization Classification of Tumors of Soft Tissue and Bone.

Illustrated with over 800 colour images, this practical guide covers the unique morphology and disease spectrum in pediatric patients, ranging from normal physiologic changes to pathologic states. In addition, it covers newly described pediatric diseases, such as GATA-2 haploinsufficiency and reflects the latest WHO classification for hematolymphoid neoplasms. With the visual format of an atlas, the book provides a quick reference for trainees and physicians in hematopathology, as well as for hematologists and oncologists treating pediatric patients. An online version of the book with expandable figures can be accessed on Cambridge Core, via the code printed on the inside of the cover.

Post-mortems may have become a staple of our TV viewing, but the long history of this practice is still little known. This book provides a fresh account of the dissections that took place across early modern Europe on those who had died of a disease or in unclear circumstances. Drawing on different approaches and on sources as varied as notes taken at the dissection table, legal records and learned publications, the chapters explore how autopsies informed the understanding of pathology of all those involved. With a broad geography, including Rome, Amsterdam and Geneva, the book recaptures the lost worlds of physicians, surgeons, patients, families and civic authorities as they used corpses to understand diseases and make sense of suffering. The evidence from post-mortems was not straightforward, but between 1500 and 1750 medical practitioners rose to the challenge, proposing various solutions to the difficulties they encountered and creating a remarkable body of knowledge. The book shows the scope and diversity of this tradition and how laypeople contributed their knowledge and expectations to the wide-ranging exchanges stimulated by the opening of bodies.

Non-invasive medical diagnosis (NIMD) is as old as medical practice itself. From the earliest healers' observations of odors, skin color, and breath sounds to today's wealth of technologies, the basics remain the same and keep the role of NIMD essential to effective medical care.

Non-Invasive Instrumentation and Measurement in Medical Diagnosis is the first book dedicated to NIMD tools and techniques. Featuring emerging technologies along with traditional instruments, it describes how these non-invasive tools and techniques work and explores developments that will make NIMD simpler, more reliable, less expensive, and risk-free. Much of the material is descriptive, but the author includes rigorous mathematical analysis where appropriate. The treatment is readily accessible to readers with a background in basic algebra and ordinary differential equations, basic circuit theory, and concepts such as frequency response and transient response of linear systems.

The rapid evolution of biomedical instrumentation has meant that books just five years old are already outdated. Whether used for an upper-level, biomedical engineering class or as a reference for medical students, healthcare professional, physicists, or physiologists, Non-Invasive Instrumentation and Measurement in Medical Diagnosis stands alone in presenting the state of NIMD art and science.