This revised edition is prepared in such a manner that will help the second year MBBS students to prepare for their MBBS exam as well as for the PG entrances. The chapter review part of each chapter is revised and updated in such a way that by studying this book, the students can easily solve the long essays, short notes of MBBS exams as well as MCQs of various PG entrances.

Provides important points of each topic in continuous manner not in parts as given in previous guides. This book consists of theory of each topic followed by its questions so theory portion helps you to solve new questions. This pattern of book allows you to revise whole infectious diseases very clearly and quickly. It provides sufficient matter which can be revised without any problem. Topic and chapter-wise arranged explanatory series. Synopsis of every chapter helps in solving new questions. The very important points given in single unit 'Revision at a Glance'. Thoroughly revised and edited by a group of microbiologists. Simple text and mnemonics, to make things easy. Provides detailed coverage of immunology and parasitology. Provides the most essential facts in flow diagrams and tabulation with an easy-to-remember format. The focus of the book is to enable everyone to solve forthcoming questions.

Ground-breaking, evidence-based book asks how many lives were lost because of Chinas negligence about lab-leaked SARS-CoV-2. In a disturbing reconstruction of events by two of the most reputable scientists in the world, a new book reveals for the first time how Chinese authorities and elite Wuhan scientists knew about SARS-CoV-2s menacing biological features from the start but remain silent to this day. In The Origin of the Virus (Clinical Press) Dr Steven Quay and Prof Angus Dalgleish, working with Italian reporter Paolo Barnard, show how China engaged in lies, omissions and obfuscations to cover up the laboratory origin of the virus. Had they immediately alerted the international community and policymakers of the extremely pathogenic molecular machinery present in SARS-CoV-2's genome, very large numbers of lives may have been spared, argue Quay, Dalgleish and Barnard. The authors provide a shocking account of the extreme experiments that led to the outbreak of the worst pandemic since the 1918 Spanish influenza. They broaden the censure to explain why some American and British scientists thwarted a proper investigation of the origin of COVID-19. Despite its impeccable scientific grounding the book is both a readable and gripping account that, for the first time, allows the public to partake in what lies at the heart of the many scandals surrounding the birth of the most deadly virus in modern times.

Microbiology for the Health Professions: A Case Study Approach features a unique focus on the basic microbiology required for students in nursing and allied health professions. The text uses a case study approach to allow students to experience real-life scenarios of infectious disease in order to discover the epidemiology, pathogenesis, disease manifestation, diagnosis, treatment, and prevention of specific infectious microorganisms. Opening chapters describe the importance of microbiology to the health professions, identify the differences between pathogenic and non-pathogenic microorganisms, and present chemistry basics for microbiology. Students learn about prokaryotic and eukaryotic cell structure, microbial metabolism and growth, the transmission and epidemiology of microorganisms, and mechanisms of infection establishment and pathogenesis. Additional chapters address basic microbial genetics, viruses, parasites, fungal pathogens, nosocomial infections, global microbiology, and more. Each chapter includes an introduction, reflection questions, summaries, key takeaways, case scenarios, and post-reading questions to support the learning experience and increase retention of the material. Microbiology for the Health Professions is an exemplary and immersive resource for courses and programs in nursing and allied health professions.

Volume Immunodeficiency Diseases in Springer's gold-standard reference work on medical immunology focuses on infectious diseases. In tandem with its three counterpart volumes it offers the most wide-ranging and authoritative repository of knowledge on infectious diseases, with readily accessed contributions by the world's leading authorities on the subject. The encyclopedia covers the material from all angles, with more than 1000 pages of essays on the genetics, physiology, metabolism, pathogenesis and applied microbiology of all known infectious diseases, and includes access to an e-reference work that will include ongoing updates reflecting the latest advances in the field. An outstanding new resource of immense value to a wide range of medical researchers and practitioners, the encyclopedia features a user-friendly subdivision of diseases according to their affective locus in the human body. The sections cover integumentary, skeletal, respiratory, digestive, urinary, and reproductive transmissible pathogens. This high-profile encyclopedia will be an essential addition to academic libraries worldwide.

Gain the knowledge and skills you need to succeed as a clinical lab technician! Textbook of Diagnostic Microbiology, 7th Edition uses a reader-friendly "building-block" approach to help you learn the essentials of diagnostic microbiology. Featuring full-color drawings and photos, this text helps you learn to identify significant isolates in the lab and to develop the critical thinking and problem-solving skills necessary to the accurate diagnosis of infectious diseases. Written by noted educators Connie R. Mahon and Donald C. Lehman, this edition adds new content on SARS-CoV-2 and COVID-19, along with the latest information on prevention, treatment modalities, and CDC guidelines. Building-block approach encourages you to use previously learned information in mastering new material. Full-color photographs and photomicrographs make it easier to understand and apply diagnostic microbiology concepts. Case studies describe clinical and laboratory findings, offering opportunities to correlate observations with possible etiologic agents and to build critical thinking and problem-solving skills. Hands-on procedures in the appendices describe techniques used in the lab setting. Issues to Consider boxes list important points to think about while reading the chapter. Case Checks in each chapter highlight specific points in the text and show how they connect to case studies. Bolded key terms with abbreviations are listed at the beginning of each chapter, showing the most important and relevant terms in each chapter. Learning Objectives at the beginning of each chapter supply you with a measurable learning outcome to achieve by completing the material. Points to Remember sections at the end of each chapter provide a bulleted list of key concepts. Learning Assessment Questions at the conclusion of each chapter help you to think critically and to evaluate how well you have mastered the material. Agents of Bioterror and Forensic Microbiology chapter provides the most current information about these important topics. Lab manual on the Evolve website reinforces concepts with real-life scenarios and review questions. Glossary at the end of the book supplies you with a quick reference for looking up definitions of key terms. NEW! Information about SARS-CoV-2 and COVID-19 is added to this edition. NEW! Updated content is included throughout the book, and several chapters are reorganized and refocused. NEW! Enterobacteriaceae chapter is updated.

The interactions of cells with their surrounding extracellular matrix (ECM) plays a pivotal role in driving normal cell behavior, from development to tissue differentiation and function. At the cellular level, organ homeostasis depends on a productive communication between cells and ECM, which eventually leads to the normal phenotypic repertoire that characterize each cell type in the organism. A failure to establish these normal interactions and to interpret the cues emanating from the ECM is one of the major causes in abnormal development and the pathogenesis of multiple diseases. To recognize and act upon the biophysical signals that are generated by the cross talk between cells and ECM, the cells developed specific receptors, among them a unique set of receptor tyrosine kinases (RTKs), known as the Discoidin Domain Receptors (DDRs). The DDRs are the only RTKs that specifically bind to and are activated by collagen, a major protein component of the ECM. Hence, the DDRs are part of the signaling networks that translate information from the ECM, and thus they are key regulators of cell-matrix interactions. Under physiological conditions, DDRs control cell and tissue homeostasis by acting on collagen sensors; transducing signals that regulate cell polarity, tissue morphogenesis, cell differentiation, and collagen deposition. DDRs play a key role in diseases that are characterized by dysfunction of the stromal component, which lead to abnormal collagen deposition and the resulting fibrotic response that disrupt normal organ function in disease of the cardiovascular system, lungs and kidneys, just to mention a few. In cancer, DDRs are hijacked by tumor and stromal cells to disrupt normal cell-collagen communication and initiate pro-oncogenic programs. Importantly, several cancer types exhibit DDR mutations, which are thought to alter receptor function, and contribute to cancer progression. Therefore, the strong causative association between altered RTK function and disease it is been translated today in the development of specific tyrosine kinase inhibitors targeting DDRs for various disease conditions. In spite of the accumulating evidence highlighting the importance of DDRs in health and diseases, there is still much to learn about these unique RTKs, as of today there is a lack in the medical literature of a book dedicated solely to DDRs. This is the first comprehensive volume dedicated to DDRs, which will fill a gap in the field and serve those interested in the scientific community to learn more about these important receptors in health and disease.

This research volume examines the available alternative, complementary, pharmaceutical and vaccine methods for treating, mitigating, or preventing COVID-19. Coverage includes traditional Chinese medicine, herbal remedies, nutraceutical/dietary options, and drug/vaccine therapies. All the methods discussed will be critically examined to provide readers with a full, unbiased overview that includes pros/cons of each method. While the nature of COVID-19 is still being studied, and new research and theories are being published daily, this book endeavors to provide readers with a comprehensive summary of current research on alternative and mainstream treatment and prevention methods.

This title highlights the current and topical areas of research in this rapidly growing field. Expert authors from around the world provide the latest insights into the mechanisms these fascinating organisms use to survive.

Extensively revised and updated, the new edition of this valuable reference work provides a comprehensive and up-to-date analysis of the current knowledge and new research in Bacillus molecular and cellular biology.