Edward J. Massaro and a panel of leading biomedical researchers and
clinical practitioners review, in-depth, the status of our current
knowledge concerning the biochemistry of copper in general and its
role in health and disease in particular. Drawing on the wealth of
new information emerging from the molecular biology revolution,
these experts survey the most important research areas of copper
pharmacology and toxicology, including copper proteins and
transport, copper toxicity and therapeutics, and copper metabolism
and homeostasis. They also discuss the molecular pathogenesis of
copper in a variety of metabolic diseases, Menkes and Wilson's
diseases and occipital horn syndrome, as well as the role of copper
in Parkinson's disease, prion disease, familial amytrophic lateral
sclerosis (ALS), and Alzheimer's disease.
General
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