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Books > Medicine > Clinical & internal medicine > Gastroenterology
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Gallstones - Pathogenesis and Treatment (Hardcover, 2004 ed.)
Loot Price: R4,606
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Gallstones - Pathogenesis and Treatment (Hardcover, 2004 ed.)
Series: Falk Symposium, 139
Expected to ship within 10 - 15 working days
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This book, the proceedings of the Falk Syposium No. 139 on
"Gallstones: Pathogenesis and Treatment", held in Freiburg,
Germany, on January 15-16, 2004, reflects the tremendous advances
in the field of biliary diseases both at the genetic and cellular
as well as the clinical levels. In industrialized countries,
gallstones are a frequent clinical entity with a prevalence of
10-15%. In clinical practice one can differentiate between
cholesterol stones, black pigment stones and brown pigment stones.
80-90% of gallbladder stones are cholesterol stones, 10--20% are
black pigment stones. The prevalence of cholesterol stones
increases with age and in Europe in the 70+ age group reaches about
20% in males and about 30% in females. Gallstones and gallstone
diseases, therefore, are a frequent and important clinical problem.
The book addresses the basic aspects of gallstone pathogenesis as
well as the non-surgical and surgical treatment of gallstone
diseases. Of particular interest are the epidemiology and genetics
of gallstone formation, with definition of risk factors, in
particular of genetic predispositions. Other major aspects are the
hepatocellular and bilary transport mechanisms that predispose to
the formation of gallstones. Apart from cholesterol and lipid
transport and absorption, gallbladder function plays a central role
in gallstone formation. Another clinically very relevant topic is
the treatment of gallstone diseases by drugs, endoscopic and other
non-surgical interventions, and surgery, as well as the long-term
outcome of therapeutic interventions. The volume concludes with a
state-of-the-art chapter on "Gallstone Research in the Post-Genomic
Era". Gallstones: Pathogenesis and Treatment is an excellent update
on the pathogenesis of gallstones as well as on the treatment of
gallstone diseases, written by an international faculty of
outstanding clinicans and scientists. The book will, therefore, be
of great interest to hepatologists and gastroenterologists in
academic institutions as well as in clinical practice.
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