The development of resistance to pesticides is generally
acknowledged as one of the most serious obstacles to effective pest
control today. Since house flies first developed resistance to DDT
in 1946, more than 428 species of arthropods, at least 91 species
of plant pathogens, five species of noxious weeds and two species
of nematodes were reported to have developed strains resistant to
on or more pesticides. A seminar of U. S. and Japanese scientists
was held in Palm Springs, California, during December 3-7, 1979,
under the U. S. -Japan Cooperative Science Program, in order to
evaluate the status of research on resistance and to discuss
directions for future emphasis. A total of 32 papers were presented
under three principal topics: Origins and Dynamics of Resistance
(6), Mechanisms of Resistance (18), and Suppression and Management
of Resistance (8). The seminar was unique in that it brought
together for the first time researchers from the disciplines of
entomology, plant pathology and weed science for a comprehensive
discussion of this common problem. Significant advances have been
identified in (a) the development of methods for detection and
monitoring of resistance in arthropods (electrophoresis, diagnostic
dosage tests) and plant pathogens, (b) research on biochemical and
physiological mechanisms of resis tance (cytochrome p450,
sensitivity of target site, gene regulation), (c) the
identification and quantification of biotic, genetic and
operational factors influencing the evolution of resistance, and
(d) the exploration of pest management approaches incorporating
resis tance-delaying measures."
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