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ACE Inhibitors in Hypertension - A Guide for General Practitioners (Paperback, Softcover reprint of the original 1st ed. 1992)
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ACE Inhibitors in Hypertension - A Guide for General Practitioners (Paperback, Softcover reprint of the original 1st ed. 1992)
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ACE inhibitors are one of the most exciting and interesting of
recent medical developments. They fit the patho-physiologica1
processes of cardiovascular disease with fascinating precision and
are a constant stimulus to the acquisition of greater understanding
of the mechanisms involved and of the mode of action of the drugs
themselves. There is still much to be learned, especially about the
wider effects of the drugs, their precise mode and site of action
and about differences between the different preparations. ACE
inhibitors are of proven benefit to patients with chronic
congestive heart failure and are the latest in the series of drugs
used in the treatment of hypertension. Interest in the treatment of
hypertension has paralleled the development of hypotensive drugs
and the realisation that long-term prognosis could be significantly
improved. The treatment of hypertension has progressed in stages
following the development of a succession of increasingly effective
drugs, each allowing a greater proportion of patients to be treated
with fewer and fewer side-effects. First, the ganglion-blocking
agents such as hexamethonium and guan ethidine transformed the
outlook for patients with malignant hypertension but proved too
unpleasant for routine use in other forms of hypertension."
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