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Imaging Life - Biological Systems from Atoms to Tissues (Hardcover)
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Imaging Life - Biological Systems from Atoms to Tissues (Hardcover)
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This volume provides an overview of a variety of approaches to
biological image analysis, which allow for the study of living
organisms at all levels of complexity and organization. These
organisms range from individual macromolecules to subcellular and
cellular volumes, tissues and microbial communities. Such a
"systems biology" understanding of life requires the combination of
a variety of imaging techniques, and with it an in-depth
understanding of their respective strengths and limitations, as
well as their intersection with other techniques. Howard, Brown,
and Auer show us that the integration of these imaging techniques
will allow us to overcome the reductionist approach to biology that
dominated the twentieth century, which was aimed at examining the
physical and chemical properties of life's constituents, one
macromolecule at a time. However, while based on the laws of
physics and chemistry, life is not simply a set of chemical
reactions and physical forces; it features an exquisite
spatiotemporal organization that allows an inconceivably large
number of chemical processes to coexist, refined by billions of
years of evolutionary experimentation.
And yet, many fundamental questions remain largely unanswered;
Imaging Life argues that we are just now beginning to address the
spatiotemporal organizational component of living processes.
"Imaging" is needed in order to reveal the spatiotemporal
relationships between components, and thus to understand
organizational guiding principles of living systems. Only through
imaging will we be able to decipher the mechanisms and the
marvelous organization that enable and sustain the mystery of life.
Imaging Life shows us how biology is beginning to do just that.
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