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The Pathogenesis of Bacterial Infections (Paperback, Softcover reprint of the original 1st ed. 1985)
Loot Price: R2,851
Discovery Miles 28 510
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The Pathogenesis of Bacterial Infections (Paperback, Softcover reprint of the original 1st ed. 1985)
Series: Bayer-Symposium, 8
Expected to ship within 10 - 15 working days
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G. G. Jackson The pathogenesis of bacterial infection defines the
dynamics at an interface of ecologic association of bacteria and
host. First, it occurs at the portal of initial contact with a per
missive target cell. The infected cell provides either a passive or
a specific receptor for the bacterium or its products, to gether
with ligands and an environment of helper and inhibiting factors.
The result is bacterial replication to produce an im balance of a
potentially commensal relation which, under other defined
conditions, would be optimal for the survival of both the host and
bacterial cells. Virulence and pathogenesis are both absolute and
relative terms. They must be interpreted strictly according to the
circumstances of site-specific inter actions of bacterial and host
cells, membrane composition, structure, characteristics, and
environmental substances. The bacteria themselves may have,
acquire, or switch on or off under certain conditions, the products
or properties that produce cellular damage that we recognize as
virulence. Another result of bacterial infection may be to
stimulate a normal host cell function to perform at a
pathophysiologic level, causing illness that we recognize as
virulence. A third marker of virulence may be the ability to invade
a cell or tissue barrier and produce a pathologic effect at a site
that is remote from the portal of commensal association or
pathologic entry."
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