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Books > Medicine > Surgery > Orthopaedics & fractures
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Bone Morphogenetic Protein And Collagen: An Advances In Tissue Banking Specialist Publication (Hardcover)
Loot Price: R2,446
Discovery Miles 24 460
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Bone Morphogenetic Protein And Collagen: An Advances In Tissue Banking Specialist Publication (Hardcover)
Series: Allografts In Bone Healing: Biology And Clinical Applications, 2
Expected to ship within 12 - 19 working days
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What are bone morphogenetic proteins (BMPs) and how can they be
used in orthopaedic practice? Ever since Urist proposed in 1976
that protein factors from cortical bone appeared to modulate bone
healing in animals, there has been a search for these mysterious
osteoinductive components. Now that their structure has been
elucidated, they have been purified and cloned, and are now
available for the improvement of bone healing. The best source of
BMPs is demineralised bone. This bone allograft is used to achieve
greater osteoinductive capacity. But are the actions procurement,
processing, demineralisation and sterilisation harmful to the BMPs?
Unless the BMPs can be assayed, neither their clinical nor their
scientific effectiveness can be appraised. All these aspects are
logically and scientifically described in this volume. In addition,
there is a review of the biochemistry of one of the two main
components of bone, namely collagen. This subject is itself a
confusing but rapidly growing field. This comprehensive review
describes the procedures for building up bone in vivo and in vitro.
Bone Morphogenetic Proteins and Collagen answers most of the
questions of orthopaedic surgeons and tissue bankers on how BMPs
can be produced and used to their maximum effectiveness. Contents:
From Bone Allografts to Synthetic Bone Grafts: Bone Morphogenetic
Proteins and Osteoinduction; The Osteoinductive Properties of
Demineralised Bone Matrix Grafts; Processing Factors Contributing
to Production of Maximally Osteoinductive Demineralised Ground
Bone; Clinical Effectiveness of Demineralised Bone Matrix Assayed
in Human Cell Culture; The Influence of Sterilization on the
Osteoinductive Properties of Bone inRat Bone Marrow Cell Culture;
Collagen Biochemistry: An Overview. Readership: Orthopaedic
surgeons who use tissue allografts in bone and related
reconstructions.
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