von Willebrand disease (VWD) is an inherited bleeding disorder that
is caused by deficiency or dysfunction of von Willebrand factor
(VWF), a plasma protein that mediates the initial adhesion of
platelets at sites of vascular injury and also binds and stabilizes
blood clotting factor VIII (FVIII) in the circulation. This book
examines the need for more information on VWD prevalence and the
relationship between low VWF levels of bleeding symptoms or risk
and improving clinical and laboratory diagnostic tools.
General
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