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Renal Pathology in Biopsy - Light, Electron and Immunofluorescent Microscopy and Clinical Aspects (Paperback, Softcover reprint of the original 1st ed. 1978)
Loot Price: R4,473
Discovery Miles 44 730
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Renal Pathology in Biopsy - Light, Electron and Immunofluorescent Microscopy and Clinical Aspects (Paperback, Softcover reprint of the original 1st ed. 1978)
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Vor die Therapie setzten die Gotter die Diagnose. Otto NiigeJi
Renal biopsy has decisively enriched renal diagnostics. Kidney
diseases may be monitored during their entire course, and new
techniques - such as immunofluorescence and electron microscopy -
may be systematically applied, resulting in novel insights into the
morphogenesis, pathogenesis, and etiology of kidney lesions. These
insights, in turn, have served as new starting points, in the
spirit of the quotation above, for the institution of causal
therapy by the clinician. This work presents our findings based on
20 years of experience in evaluating renal biopsies. As of the end
of 1974, our computer-supported, systematic clinical, morphologic,
and follow-up evaluation of case material consisted of over 2000
biopsies, including 679 examined by electron microscopy and 400 by
immunofluorescence microscopy. The subsequent 500 biopsies (400
studied by electron microscopy and 300 by immunofluorescence) were
con sidered qualitatively only. In order to enhance qualitative
findings with quantitative data, it was necessary to devise new
methods for quantifying electron-microscopic findings.
Additionally, we attempted to correlate cyto logic and
immunofluorescent observations to integrate the isolated findings
of electron microscopy into a vital cytologic pattern of reactions.
We also attempted to evaluate the almost overwhelming flood of
publications, especially those appearing within the last 10 years.
The idea for this book was conceived a decade ago. At that time,
however, our own experience in renal biopsy diagnostics seemed
insufficient to sup port such a major undertaking."
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