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Necrotic Cell Death (Paperback, Softcover reprint of the original 1st ed. 2014)
Loot Price: R4,432
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Necrotic Cell Death (Paperback, Softcover reprint of the original 1st ed. 2014)
Series: Cell Death in Biology and Diseases
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Starting with discussion of basic concepts and the molecular
mechanisms of necrosis, this book looks first at several forms of
necrotic cell death that have been identified, including
necroptosis, autophagic cell death, and PARP-mediated cell death.
As necrotic cell death is increasingly known to play a critical
role in many physiological processes, the next chapters discuss its
effect on metabolism, inflammation, immunity, and development.
Necrotic cell death is closely implicated in human diseases like
cancer, so the next chapters examine its relevance to human
diseases, and final chapters cover methodologies for measuring
necrosis. This book presents comprehensive coverage of necrosis
from recognized experts from leading academic and medical
institutions around the world. In contrast to apoptosis,
well-defined as a form of programmed cell death, necrosis used to
be considered as accidental (i.e., non-programmed) cell death,
usually in response to a severe injury. Accumulating evidence now
suggests, however, that necrosis is also programmed and controlled
by distinctive "death machinery" in response to various stimuli
like oxidative stress or DNA damage.
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