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Books > Science & Mathematics > Biology, life sciences > Cellular biology

Molecular Biology of the Cell 6E - The Problems Book (Paperback, 6th New edition): John Wilson, Tim Hunt Molecular Biology of the Cell 6E - The Problems Book (Paperback, 6th New edition)
John Wilson, Tim Hunt
R951 R808 Discovery Miles 8 080 Save R143 (15%) Shipped within 7 - 13 working days

The Problems Book helps students appreciate the ways in which experiments and simple calculations can lead to an understanding of how cells work by introducing the experimental foundation of cell and molecular biology. Each chapter reviews key terms, tests for understanding basic concepts, and poses research-based problems. The Problems Book has been designed to correspond with the first twenty chapters of Molecular Biology of the Cell, Sixth Edition.

Essential Cell Biology (Paperback, Fifth International Student Edition): Bruce Alberts, Karen Hopkin, Alexander D Johnson,... Essential Cell Biology (Paperback, Fifth International Student Edition)
Bruce Alberts, Karen Hopkin, Alexander D Johnson, David Morgan, Martin Raff, …
R1,511 Discovery Miles 15 110 Shipped within 7 - 11 working days

This text features lively, clear writing and exceptional illustrations, making it the ideal textbook for a first course in both cell and molecular biology. Thoroughly revised and updated, the Fifth Edition maintains its focus on the latest cell biology research. For the first time ever, Essential Cell Biology will come with access to Smartwork5, Norton's innovative online homework platform, creating a more complete learning experience.

Gene Machine - The Race to Decipher the Secrets of the Ribosome (Paperback): Venki Ramakrishnan Gene Machine - The Race to Decipher the Secrets of the Ribosome (Paperback)
Venki Ramakrishnan 1
R260 R187 Discovery Miles 1 870 Save R73 (28%) Shipped within 7 - 11 working days

From Nobel Prize winner Venki Ramakrishnan `Beyond superb' Bill Bryson `A wonderful book' Ian McEwan Everyone knows about DNA. It is the essence of our being, influencing who we are and what we pass on to our children. But the information in DNA can't be used without a machine to decode it. The ribosome is that machine. Older than DNA itself, it is the mother of all molecules. Virtually every molecule made in every cell was either made by the ribosome or by proteins that were themselves made by the ribosome. Venki Ramakrishnan tells the story of the race to uncover the ribosome's enormously complex structure, a fundamental breakthrough that resolves an ancient mystery of life itself and could lead to the development of better antibiotics. A fascinating insider account, Gene Machine charts Ramakrishnan's unlikely journey from his first fumbling experiments in a biology lab to being at the centre of a fierce competition at the cutting edge of modern science.

Natural Obsessions - Striving to Unlock the Deepest Secrets of the Cancer Cell (Hardcover): Natalie Angier Natural Obsessions - Striving to Unlock the Deepest Secrets of the Cancer Cell (Hardcover)
Natalie Angier; Foreword by Lewis Thomas
R640 R499 Discovery Miles 4 990 Save R141 (22%) Shipped within 7 - 11 working days
Molecular Biology of the Cell (Paperback, 6th New edition): Bruce Alberts Molecular Biology of the Cell (Paperback, 6th New edition)
Bruce Alberts 2
R3,665 R3,001 Discovery Miles 30 010 Save R664 (18%) Shipped within 7 - 13 working days

As the amount of information in biology expands dramatically, it becomes increasingly important for textbooks to distill the vast amount of scientific knowledge into concise principles and enduring concepts.As with previous editions, Molecular Biology of the Cell, Sixth Edition accomplishes this goal with clear writing and beautiful illustrations. The Sixth Edition has been extensively revised and updated with the latest research in the field of cell biology, and it provides an exceptional framework for teaching and learning. The entire illustration program has been greatly enhanced.Protein structures better illustrate structure-function relationships, icons are simpler and more consistent within and between chapters, and micrographs have been refreshed and updated with newer, clearer, or better images. As a new feature, each chapter now contains intriguing openended questions highlighting "What We Don't Know," introducing students to challenging areas of future research. Updated end-of-chapter problems reflect new research discussed in the text, and these problems have been expanded to all chapters by adding questions on developmental biology, tissues and stem cells, pathogens, and the immune system.

Cellular Biophysics and Modeling - A Primer on the Computational Biology of Excitable Cells (Paperback): Greg Conradi Smith Cellular Biophysics and Modeling - A Primer on the Computational Biology of Excitable Cells (Paperback)
Greg Conradi Smith
R856 Discovery Miles 8 560 Shipped within 7 - 12 working days

What every neuroscientist should know about the mathematical modeling of excitable cells. Combining empirical physiology and nonlinear dynamics, this text provides an introduction to the simulation and modeling of dynamic phenomena in cell biology and neuroscience. It introduces mathematical modeling techniques alongside cellular electrophysiology. Topics include membrane transport and diffusion, the biophysics of excitable membranes, the gating of voltage and ligand-gated ion channels, intracellular calcium signalling, and electrical bursting in neurons and other excitable cell types. It introduces mathematical modeling techniques such as ordinary differential equations, phase plane, and bifurcation analysis of single-compartment neuron models. With analytical and computational problem sets, this book is suitable for life sciences majors, in biology to neuroscience, with one year of calculus, as well as graduate students looking for a primer on membrane excitability and calcium signalling.

Molecular Cell Biology (Hardcover, 8th Revised edition): Arnold Berk, Chris A Kaiser, Harvey Lodish, Angelika Amon, Hidde... Molecular Cell Biology (Hardcover, 8th Revised edition)
Arnold Berk, Chris A Kaiser, Harvey Lodish, Angelika Amon, Hidde Ploegh, …
R1,898 Discovery Miles 18 980 Shipped within 7 - 12 working days

With its acclaimed author team, cutting-edge content, emphasis on medical relevance, and coverage based on key experiments, Molecular Cell Biology has justly earned an impeccable reputation as an exciting and authoritative textbook. Avoiding an encyclopedic approach, the book grounds its coverage in the experiments that define our understanding of cell biology, engaging students with the exciting breakthroughs that define the field's history and point to its future. The authors, all world-class researchers and teachers, incorporate medically relevant examples where appropriate to help illustrate the connections between cell biology and health and human disease. Molecular Cell Biology is available with LaunchPad. LaunchPad combines an interactive ebook with high-quality multimedia content and ready-made assessment options, including LearningCurve adaptive quizzing. See `Instructor Resources' and `Student Resources' for further information.

Laser Imaging and Manipulation in Cell Biology (Hardcover): Francesco S. Pavone Laser Imaging and Manipulation in Cell Biology (Hardcover)
Francesco S. Pavone
R2,991 R2,099 Discovery Miles 20 990 Save R892 (30%) Shipped within 7 - 13 working days

Here, the editor has gathered a team of international experts to present the latest advances in the field of laser imaging and manipulation techniques. The result is broad coverage of the interactions with biological samples to perform novel optical manipulation operations, both on the cellular and tissue levels.
Of interest to physicists working and researching laser tissue mechanisms, cell biologists investigating new imaging and manipulation operation on the cellular level, medical doctors working with new laser therapies and diagnostic tools, as well as engineers developing new technologies in the field of optics and lasers.

Receptor Biology (Paperback): Anne E. Kruchten, Michael Roberts Receptor Biology (Paperback)
Anne E. Kruchten, Michael Roberts
R1,643 R1,170 Discovery Miles 11 700 Save R473 (29%) Shipped within 7 - 13 working days

This book is geared to every student in biology, pharmacy and medicine who needs to become familiar with receptor mediated signaling. The text starts with explaining some basics in membrane biochemistry, hormone biology and the concept of receptor based signaling as the main form of communication between cells and of cells with the environment. It goes on covering each receptor superfamily in detail including their structure and evolutionary context. The last part focusses exclusively on examples where thorough knowledge of receptors is critical: pharmaceutical research, developmental biology, neurobiology and evolutionary biology. Richly illustrated, the book is perfectly suited for all courses covering receptor based signaling, regardless whether they are part of the biology, medicine or pharmacology program.

Concepts and Case Studies in Chemical Biology (Paperback): Herbert Waldmann, Petra Janning Concepts and Case Studies in Chemical Biology (Paperback)
Herbert Waldmann, Petra Janning
R1,179 R852 Discovery Miles 8 520 Save R327 (28%) Shipped within 7 - 13 working days

Retaining the proven didactic concept of the successful "Chemical Biology - Learning through Case Studies", this sequel features 27 new case studies, reflecting the rapid growth in this interdisciplinary topic over the past few years. Edited by two of the world's leading researchers in the field, this textbook introduces students and researchers to the modern approaches in chemical biology, as well as important results, and the techniques and methods applied. Each chapter presents a different biological problem taken from everyday lab work, elucidated by an international team of renowned scientists. With its broad coverage, this is a valuable source of information for students, graduate students, and researchers working on the borderline between chemistry, biology, and biochemistry.

Principles of Computational Cell Biology - From Protein Complexes to Cellular Networks (Paperback, 2nd Edition): Volkhard Helms Principles of Computational Cell Biology - From Protein Complexes to Cellular Networks (Paperback, 2nd Edition)
Volkhard Helms
R1,985 R1,407 Discovery Miles 14 070 Save R578 (29%) Shipped within 7 - 13 working days

Computational cell biology courses are increasingly obligatory for biology students around the world but of course also a must for mathematics and informatics students specializing in bioinformatics. This book, now in its second edition is geared towards both audiences. The author, Volkhard Helms, has, in addition to extensive teaching experience, a strong background in biology and informatics and knows exactly what the key points are in making the book accessible for students while still conveying in depth knowledge of the subject. Besides a greatly increased focus on RNA biology and epigenetics, new topics such as intracellular trafficking, particle tracking, and more cellular programs e.g. circadian rhythms, apoptosis and cell differentiation, have been included. In addition, the book features supplementary material on the web including slides for presentations.

Fertilization - The Beginning of Life (Paperback): Brian Dale Fertilization - The Beginning of Life (Paperback)
Brian Dale
R870 R659 Discovery Miles 6 590 Save R211 (24%) Shipped within 7 - 11 working days

This book introduces readers to the fascinating interaction of specialized gamete cells, forming the early embryo and a blueprint of new life. Readers will gain a thorough understanding of the complex physiological events and mechanical processes - such as ionic regulation, metabolism and intracellular signalling - to decipher cause and effect in fertilization. Wide-ranging in its approach, this book describes fertilization as a highly conserved mechanism throughout the animal kingdom, taking case studies from echinoderms, ascidians, amphibians and mammals through to other phyla. An excellent companion to undergraduate and postgraduate students of medicine, veterinary and biological sciences, this text provides an underpinning of the mechanisms of fertilization that inform assisted reproduction practice and research in medicine and agriculture. It explores the detailed phases before fertilization: the oocyte as a quiescent cell, attracting its partner gamete, followed by a cascade of pre-determined physiological events, to form the dynamic zygote cell; setting the scene for the early embryo, and beyond.

The Machinery of Life (Hardcover, 2nd ed. 2009): David S Goodsell The Machinery of Life (Hardcover, 2nd ed. 2009)
David S Goodsell
R579 R465 Discovery Miles 4 650 Save R114 (20%) Shipped within 7 - 12 working days

Imagine that we had some way to look directly at the molecules in a living organism. An x-ray microscope would do the trick, or since we re dreaming, perhaps an Asimov-style nanosubmarine (unfortunately, neither is currently feasible). Think of the wonders we could witness firsthand: antibodies atta- ing a virus, electrical signals racing down nerve fibers, proteins building new strands of DNA. Many of the questions puzzling the current cadre of sci- tists would be answered at a glance. But the nanoscale world of molecules is separated from our everyday world of experience by a daunting million-fold difference in size, so the world of molecules is completely invisible. I created the illustrations in this book to help bridge this gulf and allow us to see the molecular structure of cells, if not directly, then in an artistic rendition. I have included two types of illustrations with this goal in mind: watercolor paintings which magnify a small portion of a living cell by one million times, showing the arrangement of molecules inside, and comput- generated pictures, which show the atomic details of individual molecules. In this second edition of The Machinery of Life, these illustrations are presented in full color, and they incorporate many of the exciting scientific advances of the 15 years since the first edition."

RNA Methodologies - Laboratory Guide for Isolation and Characterization (Spiral bound, 5th edition): Robert E. Farrell RNA Methodologies - Laboratory Guide for Isolation and Characterization (Spiral bound, 5th edition)
Robert E. Farrell
R2,661 R2,240 Discovery Miles 22 400 Save R421 (16%) Shipped within 7 - 12 working days

RNA Methodologies, Fifth Edition continues its tradition of excellence in providing the most up-to-date ribonucleic acid lab techniques for seasoned scientists and graduate students alike. This edition features new material on the exploding field of microRNA as well as the methods for the profiling of gene expression, both which have changed considerably in recent years. As a leader in the field, Dr. Farrell provides a wealth of knowledge on the topic of RNA while also giving readers helpful hints from his own personal experience in this subject area. Beginning with the most contemporary, RNA Methodologies, Fifth Edition, presents the essential techniques to use when working with RNA for the experienced practitioner while at the same time providing images and examples to aid the beginner in fully understanding this important branch of molecular biology. The next generation of scientists can look to this work as a guide for ensuring high productivity and highly representative data, as well as best practices in troubleshooting laboratory problems when they arise.

Dance to the Tune of Life - Biological Relativity (Hardcover): Denis Noble Dance to the Tune of Life - Biological Relativity (Hardcover)
Denis Noble 1
R469 R376 Discovery Miles 3 760 Save R93 (20%) Shipped within 7 - 11 working days

In this thought-provoking book, Denis Noble formulates the theory of biological relativity, emphasising that living organisms operate at multiple levels of complexity and must therefore be analysed from a multi-scale, relativistic perspective. Noble explains that all biological processes operate by means of molecular, cellular and organismal networks. The interactive nature of these fundamental processes is at the core of biological relativity and, as such, challenges simplified molecular reductionism. Noble shows that such an integrative view emerges as the necessary consequence of the rigorous application of mathematics to biology. Drawing on his pioneering work in the mathematical physics of biology, he shows that what emerges is a deeply humane picture of the role of the organism in constraining its chemistry, including its genes, to serve the organism as a whole, especially in the interaction with its social environment. This humanistic, holistic approach challenges the common gene-centred view held by many in modern biology and culture.

In Vivo Cryotechnique in Biomedical Research and Application for Bioimaging of Living Animal Organs (Hardcover, 1st ed. 2016):... In Vivo Cryotechnique in Biomedical Research and Application for Bioimaging of Living Animal Organs (Hardcover, 1st ed. 2016)
Shinichi Ohno, Nobuhiko Ohno, Nobuo Terada
R3,796 R2,994 Discovery Miles 29 940 Save R802 (21%) Shipped within 7 - 12 working days

This book focuses on actual morphofunctional findings of cells and tissues in living animal organs. Medical and biological scientists need to know the real in vivo morphology and immunolocalization of the molecular components in living animal organs. Recently, the live imaging of cells and tissues of animals with fluorescence-labeled proteins by gene manipulation has become more and more popular in biological fields. Current research, meanwhile, has revealed that immunohistochemical or morphological studies exclusively depend on living animal organs. The cryotechnique is one of the most useful tools for immunohistochemistry and bioimaging of animal organs. This book describes the epoch-making cryotechnique originally developed by the editors. The book also makes the management of living animal morphology more accessible not only for biomedical researchers but also for clinical doctors, providing a valuable resource work on the current perspectives of in vivo morphology.

Chemical Biology - Learning through Case Studies (Paperback): Herbert Waldmann, Petra Janning Chemical Biology - Learning through Case Studies (Paperback)
Herbert Waldmann, Petra Janning
R1,116 R927 Discovery Miles 9 270 Save R189 (17%) Shipped within 7 - 12 working days

This first book to adopt a problem-based approach teaches the true basics of the subject through illustrated everyday case studies. The editor's extensive experience in writing textbooks and his close relationship to the authors ensure that the contributions are presented in a pedagogically uniform and highly motivating fashion. Each chapter introduces a different biological problem taken from everyday lab work, such that students learn how to think in order to solve problems in biology by using techniques and tools taken from chemistry.
A must-have for students in chemistry, biology and biochemistry.

Chemical Biology in Regenerative Medicine - Bridging Stem Cells and Future Therapies (Hardcover): Charles C. Hong, Ada Ao,... Chemical Biology in Regenerative Medicine - Bridging Stem Cells and Future Therapies (Hardcover)
Charles C. Hong, Ada Ao, Jijun Hao
R2,223 R1,566 Discovery Miles 15 660 Save R657 (30%) Shipped within 7 - 13 working days

Regenerative medicine is a highly interdisciplinary field, with contributions from medicine, engineering, and chemistry. Chemical biology plays a key role - small molecules are involved in differentiating, reprogramming and manipulating stem cells and in enabling transplantation.

In "Chemical Biology in Regenerative Medicine, "an international team of experts provides an overview of progress towards clinical application in the areas of transplantation (allogenic and autologous), manipulation of niche environment and homing, and cell reprogramming (trans-differentiation and de-differentiation). The book highlights the interdisciplinary approaches undertaken to resolve current technical problems in regenerative medicine, with special attention paid to small molecules and biomaterials engineering. It also includes an overview of the current regulatory climate and discusses the future of these therapies. Topics covered include: Wnt Signaling in Regulation of Stem CellsDirected Cardiomyogenesis of Pluripotent Stem CellsChemical Genetics in Cardiomyocyte Generation" "Challenges and New Directions for Cardiac ReprogrammingComparative Analysis of Adult Stem Cell NichesChemicals and Stem Cells for Promoting RegenerationChemically Induced Pluripotent Stem Cells (CiPSC): A Potential Chemical Biological Breakthrough in Reprogramming?An Introduction to Cellular Reprogramming: The Plasticity of Cell Fates and IdentitiesChemicals Facilitating ReprogrammingChemicals Facilitating Reprogramming: Targeting the SAM Binding Site to Identify Novel Methyltransferase InhibitorsBiomaterials for Directed differentiation

"Chemical Biology in Regenerative Medicine" is an essential overview of this emerging technology for researchers in academia, industry and clinical settings working in regenerative medicine, chemical biology, biochemistry, cell biology, biomaterials and bioengineering.

Canto Classics - On Growth and Form (Paperback): D'Arcy Wentworth Thompson Canto Classics - On Growth and Form (Paperback)
D'Arcy Wentworth Thompson; Edited by John Tyler Bonner
R356 R292 Discovery Miles 2 920 Save R64 (18%) Shipped within 7 - 11 working days

Why do living things and physical phenomena take the form they do? D'Arcy Thompson's classic On Growth and Form looks at the way things grow and the shapes they take. Analysing biological processes in their mathematical and physical aspects, this historic work, first published in 1917, has also become renowned for the sheer poetry of its descriptions. A great scientist sensitive to the fascinations and beauty of the natural world tells of jumping fleas and slipper limpets; of buds and seeds; of bees' cells and rain drops; of the potter's thumb and the spider's web; of a film of soap and a bubble of oil; of a splash of a pebble in a pond.

Development of the Nervous System (Hardcover, 4th edition): Development of the Nervous System (Hardcover, 4th edition)
R1,923 R1,559 Discovery Miles 15 590 Save R364 (19%) Shipped within 7 - 12 working days

Development of the Nervous System, Fourth Edition provides an informative and up-to-date account of our present understanding of the basic principles of neural development as exemplified by key experiments and observations from past and recent times. This book reflects the advances made over the last few years, demonstrating their promise for both therapy and molecular understanding of one of the most complex processes in animal development. This information is critical for neuroscientists, developmental biologists, educators, and students at various stages of their career, providing a clear presentation of the frontiers of this exciting and medically important area of developmental biology. The book includes a basic introduction to the relevant aspects of neural development, covering all the major topics that form the basis of a comprehensive, advanced undergraduate and graduate curriculum, including the patterning and growth of the nervous system, neuronal determination, axonal navigation and targeting, neuron survival and death, synapse formation and plasticity.

The Bethesda System for Reporting Cervical Cytology - Definitions, Criteria, and Explanatory Notes (Paperback, 3rd ed. 2015):... The Bethesda System for Reporting Cervical Cytology - Definitions, Criteria, and Explanatory Notes (Paperback, 3rd ed. 2015)
Ritu Nayar, David Wilbur
R1,129 R639 Discovery Miles 6 390 Save R490 (43%) Shipped within 7 - 12 working days

This book offers clear, up-to-date guidance on how to report cytologic findings in cervical, vaginal and anal samples in accordance with the 2014 Bethesda System Update. The new edition has been expanded and revised to take into account the advances and experience of the past decade. A new chapter has been added, the terminology and text have been updated, and various terminological and morphologic questions have been clarified. In addition, new images are included that reflect the experience gained with liquid-based cytology since the publication of the last edition in 2004. Among more than 300 images, some represent classic examples of an entity while others illustrate interpretative dilemmas, borderline cytomorphologic features or mimics of epithelial abnormalities. The Bethesda System for Reporting Cervical Cytology, with its user-friendly format, is a "must have" for pathologists, cytopathologists, pathology residents, cytotechnologists, and clinicians.

Stem Cells, 2nd Edition (Hardcover, 2nd Revised edition): Evelyn B Kelly Stem Cells, 2nd Edition (Hardcover, 2nd Revised edition)
Evelyn B Kelly
R860 Discovery Miles 8 600 Shipped within 7 - 11 working days
Plant Cells and their Organelles (Hardcover): William V. Dashek, Gurbachan S. Miglani Plant Cells and their Organelles (Hardcover)
William V. Dashek, Gurbachan S. Miglani
R1,651 R1,178 Discovery Miles 11 780 Save R473 (29%) Shipped within 7 - 13 working days

Plant Cells and Their Organelles provides a comprehensive overview of the structure and function of plant organelles. The text focuses on subcellular organelles while also providing relevant background on plant cells, tissues and organs. Coverage of the latest methods of light and electron microscopy and modern biochemical procedures for the isolation and identification of organelles help to provide a thorough and up-to-date companion text to the field of plant cell and subcellular biology. The book is designed as an advanced text for upper-level undergraduate and graduate students with student-friendly diagrams and clear explanations.

Plant Cell Biology (DVD-ROM): Brian E.S. Gunning Plant Cell Biology (DVD-ROM)
Brian E.S. Gunning
R1,953 Discovery Miles 19 530 Shipped within 7 - 12 working days

The DVD contains approx. 2,000 images and more than 250 movies of the cell biology and structure-function relationships of subcellular components of plant cells.

Most forms of microscopy and most forms of sample preparation are included (TEM, SEM, FESEM, NSEM, tomography, confocal, wide-field, DIC, fluorescence, immuno-localisations, GFP and other probes, etc.). The superior quality given by high-pressure freezing/freeze-substitution is featured in all chapters. Particular emphasis is placed on movie recording of dynamic processes in live cells, thus making avaiable events which few teachers or students can hope to see for themselves.

Program facilities include hierarchical menus, comprehensive navigation and progress-monitoring aids, detailed descriptions of all images, ability to export images, and a slide-show module that allowas pre-selection of sequences of images/movies for use in one-click presentations or tutorial exercises.

Essential Cell Biology (Hardcover, 4th New edition): Bruce Alberts, Dennis Bray, Karen Hopkin, Alexander D Johnson, Julian... Essential Cell Biology (Hardcover, 4th New edition)
Bruce Alberts, Dennis Bray, Karen Hopkin, Alexander D Johnson, Julian Lewis, …
R3,382 Discovery Miles 33 820 Shipped within 7 - 12 working days

Essential Cell Biology provides a readily accessible introduction to the central concepts of cell biology, and its lively, clear writing and exceptional illustrations make it the ideal textbook for a first course in both cell and molecular biology. The text and figures are easy-to-follow, accurate, clear, and engaging for the introductory student. Molecular detail has been kept to a minimum in order to provide the reader with a cohesive conceptual framework for the basic science that underlies our current understanding of all of biology, including the biomedical sciences. The Fourth Edition has been thoroughly revised, and covers the latest developments in this fast-moving field, yet retains the academic level and length of the previous edition. The book is accompanied by a rich package of online student and instructor resources, including over 130 narrated movies, an expanded and updated Question Bank. Essential Cell Biology, Fourth Edition is additionally supported by the Garland Science Learning System. This homework platform is designed to evaluate and improve student performance and allows instructors to select assignments on specific topics and review the performance of the entire class, as well as individual students, via the instructor dashboard. Students receive immediate feedback on their mastery of the topics, and will be better prepared for lectures and classroom discussions. The user-friendly system provides a convenient way to engage students while assessing progress. Performance data can be used to tailor classroom discussion, activities, and lectures to address students' needs precisely and efficiently. For more information and sample material, visit http://garlandscience.rocketmix.com/.

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