This book describes the interlaced histories of life and oxygen. It
opens with the generation of oxygen in ancient stars and its
distribution to newly formed planets like the Earth. Free O2 was
not available on the early Earth, so the first life forms had to be
anaerobic. Life introduced free O2 into the environment through the
evolution of photosynthesis, which must have been a disaster for
many anaerobes. Others found ways to deal with the toxic reactive
oxygen species and even developed a much more efficient
oxygen-based metabolism. The authors vividly describe how the
introduction of O2 allowed the burst of evolution that created
today's biota. They also discuss the interplay of O2 and CO2, with
consequences such as worldwide glaciations and global warming. On
the physiological level, they present an overview of oxidative
metabolism and O2 transport, and the importance of O2 in human life
and medicine, emphasizing that while oxygen is essential, it is
also related to aging and many disease states.
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