In this monograph, an accurate ultrasonic method for measurement of
small motion and deformation of biological tissue is described. In
the displacement estimation based on the phase change of echoes,
the displacement estimates are biased when the center frequency of
the RF echo changes. Such an apparent change in the center
frequency could be caused by the interference of echoes from
scatterers. To reduce the influence of the center frequency
variation on the estimation of motion and deformation, an error
correcting function, which does not require the assumption that the
center frequency distributions in 2 different frames are the same,
was introduced. As a result, the proposed method provides better
strain estimates in comparison with conventional phase-sensitive
correlation methods. This monograph also shows examples of
applications of this method to measurement of small motion and
deformation of biological tissues. This method can be applied to
measurement of elasticity of dynamic tissues, such as the artery.
Also, elastic properties of static tissues can be also measured by
combining with actuation using the acoustic radiation force.
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