Books > Medicine > Clinical & internal medicine > Otorhinolaryngology (ENT)
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Eustachian Tube and Middle Ear Diseases (Paperback, Softcover reprint of the original 1st ed. 1992)
Loot Price: R2,902
Discovery Miles 29 020
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Eustachian Tube and Middle Ear Diseases (Paperback, Softcover reprint of the original 1st ed. 1992)
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For more than three decades the methods for assessing cell pro
liferation have been largely the preserve of experimental
biologists, and in their hands such techniques have contributed
greatly to our understanding of the dynamic organisation of normal
and patho logical tissues. In recent years, with the advent of
novel method ologies, there has been increased interest among both
pathologists and clinicians, particularly oncologists and others
interested in neoplasia, in assessing cell proliferation. This
interest has been stimulated by the possibility that indices of
cell proliferation may have direct clinical relevance, for example
in being useful predictors of outcome in patients with certain
forms of malignancy. In addi tion, interest in assessing cell
proliferation has been fuelled by the tremendous advances in our
understanding of the mechanisms of cell proliferation and their
deregulation in pathological processes. Consequently, the time is
ripe for a monograph critically reviewing the available methods for
assessing cell proliferation, their potential and their problems.
We have been particularly concerned to present a balanced view of
the advantages and disadvantages of different methods currently
available for assessing cell proliferation. The assessment of cell
proliferation often requires some familiarity with mathematical
methods, but in this book we have attempted to keep detailed
mathematical analyses to a minimum. We have asked exponents of each
of the well-recognised methods to critically review the tech niques
and the ways in which they may be applied to clinical mate rial."
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