Viruses have limited genome-coding capacities and must therefore
rely on their host cells to facilitate every step of the infection
cycle from the replication of their genomes, transcription and
translation of mRNAs to virus assembly. Aimed at virologists and
cell biologists"Viruses and the Nucleus" provides a comprehensive
and cohesive overview of this fascinating and fast moving field. It
compares and contrasts the ways in which DNA viruses, retroviruses
and RNA viruses interact with the host cell nucleus to bring about
replication and how they subvert the host cell function to
proliferate and survive.
Written by a team of leading experts in the field, this
multi-authored text begins with an introduction to the key nuclear
process that effect virus biology including cell cycle,
transcription, splicing and protein trafficking. It then goes on to
explore the advances that have been made in understanding the ways
in which specific viruses interact with nuclear sub-structures such
as the nucleolus and ND10s, and the implications this
interrelationship has for the cell cycle as a whole.
('Key Features' bullet points to be put in one box)
Comprehensive cross disciplinary coverage of the interrelationship
between cell biology and virology. Written by leading experts, this
authorative book provides an up to date overview of this highly
active field. Covers the latest research areas including virus
interactions with sub-nuclear structures, virus protein trafficking
into and out of the nucleus and subversion of host-cell function
through specific nuclear interactions.
Viruses and the Nucleus will be an invaluable resource for
students of virology, microbiology and cell biology aswell as those
who work within the industry.
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