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The TNF Superfamily - Methods and Protocols (Hardcover, 2014)
Loot Price: R3,584
Discovery Miles 35 840
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The TNF Superfamily - Methods and Protocols (Hardcover, 2014)
Series: Methods in Molecular Biology, 1155
Expected to ship within 12 - 17 working days
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Exploring these type II trans-membrane proteins, The TNF
Superfamily: Methods and Protocols focuses on various techniques to
investigate aspects of the TNF Superfamily members in health and
disease. Opening with protocols to understand the signaling process
of TNF family members, this detailed volume continues with
technical examples of investigating the role of TNF family members
in physiopathologies, protocols on modulation of TNF signaling by
pathogens, experimental applications of TNF-reporter mice, as well
as methodologies for various assays of TNF family members and the
production of recombinant molecules. Written for the Methods in
Molecular Biology series, chapters include introductions to their
respective topics, lists of the necessary materials and reagents,
step-by-step, readily reproducible laboratory protocols and tips on
troubleshooting and avoiding known pitfalls. Practical and ready to
use, The TNF Superfamily: Methods and Protocols will aid
researchers investigating this key family of proteins, involved in
vital processes such as providing signals for activation,
differentiation, survival and death of cells, modulation of immune
response and inflammation, hematopoiesis and osteoclastogenesis.
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