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Books > Medicine > Clinical & internal medicine > Cardiovascular medicine
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Primary Angioplasty in Acute Myocardial Infarction (Hardcover, 2nd ed. 2009)
Loot Price: R3,035
Discovery Miles 30 350
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Primary Angioplasty in Acute Myocardial Infarction (Hardcover, 2nd ed. 2009)
Series: Contemporary Cardiology
Expected to ship within 10 - 15 working days
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The past 50 years have witnessed a breathtaking evolution in the
approaches to the patient with an acute ST elevation myocardial
infarction. In the 1960s, the now commonplace cardiac intensive
care unit was but a nascent idea. Without much to offer the patient
but weeks of absolute bedrest, substantial morbidity and high rates
of mortality were the norm. Just 30 years ago, seminal discoveries
by DeWood and colleagues suggested that the culprit was plaque
rupture with thrombosis, not progressive luminal compromise.
Subsequent fibrinolyt- based strategies resulted in a halving of
the mortality of acute myocardial infarction. With the introduction
of balloon angioplasty in the late 1970s, a few interventional
cardiologists braved the question: why not perform emergency
angioplasty as a primary reperfusion strategy? Indeed, reports of
successful reperfusion via balloon angioplasty appeared (mostly in
local newspapers) as early as 1980. Despite being thought of as
heretical by mainstream cardiology, these pioneers nonetheless
persevered, proving the benefit of ''state-of-the-art'' balloon
angioplasty compared with ''state-of-t- art'' thrombolytic therapy
in a series of landmark trials published in the New England Journal
of Medicine in March of 1993. Publication of the first edition of
Primary Angioplasty in Acute Myocardial Infarction in 2002 to some
extent anticipated the widespread acceptance of primary
percutaneous coronary intervention as the standard of care. Since
then, in all respects, the evolution of emergency percutaneous
revascularization has only accelerated. The universal replacement
of balloon angioplasty with stent implantation was clearly one key.
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