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Books > Science & Mathematics > Biology, life sciences > Cellular biology
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Polyamine Cell Signaling - Physiology, Pharmacology, and Cancer Research (Paperback, Softcover reprint of hardcover 1st ed. 2006)
Loot Price: R4,284
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Polyamine Cell Signaling - Physiology, Pharmacology, and Cancer Research (Paperback, Softcover reprint of hardcover 1st ed. 2006)
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Polyamines are organic cations found in all eukaryotic cells and
intimately involved in, and required for, distinct biological
functions. An increasing body of evidence indicates that the
regulation of cellular polyamines is a central convergence point
for the multiple signaling pathways driving various cellular
functions. Over the last decade, considerable progress has been
made in und- standing the molecular functions of cellular
polyamines. These significant findings provide a fundamental basis
to not only define the exact role of polyamines in physiology, but
also to develop new therapeutic approaches for cancers and other
diseases. The major objective of this book is to provide a timely
and long lasting guide for investigators in the fields of
polyamines, physiology, pharmacology, and cancer research. It will
provide a foundation based on research and address the potential
for subsequent applications in clinical practice. Polyamine Cell
Signaling: Physiology, Pharmacology, and Cancer Research is divided
into four main parts: Part I: Polyamines in Signal Transduction of
Cell Proliferation Part II: Polyamines in Cellular Signaling of
Apoptosis, Carcinogenesis, and Cancer Therapy Part III: Polyamines
in Cell Motility and Cell-Cell Interactions Part IV: Polyamine
Homeostasis and Transport This book not only covers the current
state-of-the-art findings relevant to cellular and molecular
functions of polyamines, but also provides the underlying
conceptual basis and knowledge regarding potential therapeutic
targeting of polyamines and polyamine metabolism. These points are
addressed by int- nationally recognized experts in their
contributions to this book.
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