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Sudden Death - Causes, Risk Factors & Prevention (Hardcover)
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Sudden Death - Causes, Risk Factors & Prevention (Hardcover)
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This book dedicates the first seven chapters to cardiac
electrophysiological dysfunction that can lead to ventricular
fibrillation and sudden death. The next six chapters expand the
topics of sudden death to other causes. Brugada Syndrome is the top
cause of non-traumatic sudden death in young males of Southeastern
Asian and southern European origins. Chapters One and Two review
extensively the history and current status, mechanisms of
arrhythmias, and related gene mutations in Brugada Syndrome, and
discuss gaps in the current knowledge. Chapter Three presents
clinical studies on the A1180V and R1193Q mutations of the cardiac
sodium channel gene, SCN5A. The authors identified R1193Q mutation
in 12.8%-16% of a healthy Chinese population. This result prompted
the question of whether SCN5A mutations are still the top genetic
bases of Brugada and long QT syndromes. Chapters Four, Five and
Seven discuss the pathophysiology causes, risk factors, predictors,
prevention, and possible therapeutical strategies of sudden cardiac
death. Chapter Six reviews the scope and causes of sudden cardiac
death in athletics. Chapter Seven is dedicated to the roles of
electrical cardiac systole in sudden death. Chapter Eight reviews
sudden death related to cardiac and brain tumours, pulmonary tumour
embolism, asphyxia, massive exsanguinations, and their
pathophysiology. Chapter Nine summarises the pathophysiology of
sudden death caused by myocardial tuberculosis. Chapter Ten
introduces pathophysiology of sudden death during hot baths in deep
bathtubs, which occurs frequently in elderly people in Japan.
Chapter Eleven discusses air pollution as a trigger of sudden
death. Chapter Twelve presents biochemical, cytological and
histopathological examination of sudden unexpected death in
infancy. The last chapter of the book, Chapter Thirteen, reviews
post-mortem cardiac markers in different body fluids and their
application in forensic pathology diagnosis of sudden cardiac
death. In combination, these chapters cover a broad range of topics
about sudden death.
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