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Books > Professional & Technical > Industrial chemistry & manufacturing technologies > Industrial chemistry > Pharmaceutical technology
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In Vivo Models for Drug Discovery (Hardcover)
Loot Price: R3,552
Discovery Miles 35 520
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In Vivo Models for Drug Discovery (Hardcover)
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This one-stop reference is the first to present the complete
picture -- covering all relevant organisms, from single cells to
mammals, as well as all major disease areas, including neurological
disorders, cancer and infectious diseases.
Addressing the needs of the pharmaceutical industry, this unique
handbook adopts a broad perspective on the use of animals in the
early part of the drug development process, including regulatory
rules and limitations, as well as numerous examples from real-life
drug development projects.
After a general introduction to the topic, the expert contributors
from research-driven pharmaceutical companies discuss the basic
considerations of using animal models, including ethical issues.
The main part of the book systematically surveys the most important
disease areas for current drug development, from cardiovascular to
endocrine disorders, and from infectious to neurological diseases.
For each area, the availability of animal models for target
validation, hit finding and lead profiling is reviewed, backed by
numerous examples of both successes and failures among the use of
animal models. The whole is rounded off with a discussion of
perspectives and challenges.
Key knowledge for drug researchers in industry as well as academia.
General
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