Heart Failure (HF) is the final and common pathway of all
cardiovascular diseases. Heart Failure: Bench to Bedside helps
address a significant need to develop new paradigms and to identify
novel therapeutic targets for this pervasive disease. An
authoritative contribution to the field, this book provides a
detailed description of new findings and emerging methodologies, as
well as a critical clinical evaluation of the complex HF syndrome
and future therapies. Heart Failure: Bench to Bedside includes a
primer on gene profiling and bioenergetics of the normal heart and
a discussion of the molecular, genetic, biochemical and cellular
techniques critical to understanding HF. Further chapters discuss
cardiac remodeling, oxidative stress, and alterations in other
organs and systems that are often associated with HF. This book
thoughtfully evaluates current and forthcoming diagnostic
techniques and therapies, pharmaceutical and pharmacogenomic-based
individualized medicine, gene and cell-based therapies, and the
search for new frontiers. Heart Failure: Bench to Bedside presents
a clear view of up-to-date approaches to clinical diagnosis and
treatment, as well as offering insightful critiques of original and
creative scientific thoughts on post-genomic HF research.
General
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