This volume describes recent research in the field of
metalloproteinas es, in particular their participation in
autoimmune diseases such as r heumatoid arthritis. The work updates
current progress in matrix metal loproteinase research, reviewing
the latest developments in metallopro teinase inhibitor design and
the current status of clinical candidates . It elucidates the
structural relationships between different members of the MMP
family and provides insight into the contributions of diff erent
metalloproteinases to normal and pathological processes. Special
emphasis is given to the potential of adamlysins as therapeutic
targe ts. This volume is intended not only for those active in
research into metalloproteinases but also for those with an
interest in inflammator y diseases. Thus it addresses both academic
and industrial researchers .
General
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