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Books > Medicine > Clinical & internal medicine > Cardiovascular medicine
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Essential Hypertension 2 (Paperback, Softcover reprint of the original 1st ed. 1989)
Loot Price: R1,652
Discovery Miles 16 520
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Essential Hypertension 2 (Paperback, Softcover reprint of the original 1st ed. 1989)
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The First International Symposium on Mechanism and Treatment in
Essential Hypertension was held on October 23 and 24, 1985 in
Nagoya. The Second International Symposium, which was held on May
30,31, and June 1, 1988 in Nagoya, was a success thanks to the
endeavors of all the participants. These symposiums were made
possible by the generous support of the city of Nagoya, Aichi
Prefec ture, and various contributions. Understanding of the
mechanisms of gene (major gene, essential) hypertension is
impossible unless we comprehend the physiological properties of
arterial smooth muscle. Since Langendorff's discovery of the role
of calcium ions in muscle contraction in 1895, we have made immense
progress in our knowledge of the role of the calcium ion in the
excitation-contraction coupling of the arterial smooth mus cle.
Investigation of the molecular mechanisms controlling the cellu lar
basis of calcium ion action has been established with the discovery
of the calcium binding protein (Ebashi 1963). The participation of
the calcium induced calcium mechanism in the contraction of muscle
has been directly demonstrated by using chemically skinned smooth
muscle fibers (Endo et al. 1977). Methods for intracellular free
cal cium contents and calcium channel activity have been developed
and contribute to the study of the role of the calcium ion in
arterial smooth muscle contractility. Such recent progress promotes
study of the basic physiological, biochemical, and molecular
properties of the calcium channel, and, in the field of
hypertension research, the sodium and potassium channels."
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