Genotoxicity and DNA Repair - A Practical Approach (Hardcover, 2014)

Genotoxicity and DNA Repair: A Practical Approach provides a key reference for determining how to analyze the genotoxic activity of molecules or materials and, at the same time, serves as a useful tool for researchers in the Environmental Mutagenesis and DNA Repair fields. Focused on genotoxicity assays recommended by the "OECD guidelines for the testing of chemicals", this volume also covers other useful assays, such as some gene mutation assays, the comet assay in different species and applications, and the SMART assays of Drosophila. For all the assays, the book presents brief theoretical introductions to the topics and updated standard and modified step-by-step protocols to perform them. Special emphasis is placed on the analysis of nanoparticles, including an integrative approach analysis. The DNA Repair section includes several assays that provide information on repair activity in vitro and in vivo, as well as recent applications to study DNA repair in humans, cell cultures, and animal models. As a volume in the Methods in Pharmacology and Toxicology series, the chapters contain the kind of detail and key implementation advice that ensures reproducible results in the lab. Authoritative and invaluable, Genotoxicity and DNA Repair: A Practical Approach aims to aid scientists in their pursuit of forwarding this vital field of study.

General

Imprint:	HumanaPress
Country of origin:	United States
Series:	Methods in Pharmacology and Toxicology
Release date:	August 2014
First published:	2014
Editors:	L. Maria Sierra • Isabel Gaivao
Dimensions:	254 x 178 x 25mm (L x W x T)
Format:	Hardcover
Pages:	483
Edition:	2014
ISBN-13:	978-1-4939-1067-0
Categories:	Books > Medicine > Pre-clinical medicine: basic sciences > Medical genetics Books > Medicine > Other branches of medicine > Pharmacology > General
LSN:	1-4939-1067-1
Barcode:	9781493910670

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