Drug Metabolism and Transport - Molecular Methods and Mechanisms (Hardcover, 2005 ed.)

A compendium of proven experimental approaches and strategies for studying the bioactivation, detoxification, tissue distribution, and elimination of xenobiotics in the metabolism and/or transport of various chemicals. The authors address several of the major drug metabolizing systems, including the cytochrome P450 family, flavin-containing monooxygenases, glutathione, S-transferase, glucuronidation, N-acetylation, and sulfotransferases. Additional chapters present novel approaches to the study of: signaling pathways in the regulation of drug metabolism enzymes, how the modulation of thiols and other low molecular-weight cofactors can alter drug metabolism, and how modulation of drug metabolism pathways can influence antiviral therapy.

General

Imprint:	HumanaPress
Country of origin:	United States
Series:	Methods in Pharmacology and Toxicology
Release date:	September 2004
First published:	2005
Editors:	Lawrence H. Lash
Dimensions:	235 x 155 x 22mm (L x W x T)
Format:	Hardcover
Pages:	388
Edition:	2005 ed.
ISBN-13:	978-1-58829-324-4
Categories:	Books > Medicine > Other branches of medicine > Pharmacology > General
LSN:	1-58829-324-6
Barcode:	9781588293244

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