Cutting-edge articles review our current understanding of lipid
microdomain signaling mechanisms and their physiological and
pathological importance. The book describes the role of lipid rafts
in learning, memory, and cancer, presents the emerging evidence
that lipid rafts play critical roles in signaling pathways and the
regulation of synaptic function in the nervous system, and shows
how alterations in lipid raft metabolism are implicated in the
pathogenesis of neurodegenerative disorders. Techniques are also
described for the isolation of lipid rafts, the analysis of the
lipid and protein components of lipid rafts, the imaging of lipid
rafts in living cells, and the analysis of signal transduction in
lipid rafts.
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