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Amorphous Drugs - Benefits and Challenges (Paperback, Softcover reprint of the original 1st ed. 2018)
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Amorphous Drugs - Benefits and Challenges (Paperback, Softcover reprint of the original 1st ed. 2018)
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This book explains theoretical and technological aspects of
amorphous drug formulations. It is intended for all those wishing
to increase their knowledge in the field of amorphous
pharmaceuticals. Conversion of crystalline material into the
amorphous state, as described in this book, is a way to overcome
limited water solubility of drug formulations, in this way
enhancing the chemical activity and bioavailability inside the
body. Written by experts from various fields and backgrounds, the
book introduces to fundamental physical aspects (explaining
differences between the ordered and the disordered solid states,
the enhancement of solubility resulting from drugs amorphization,
physical instability and how it can be overcome) as well as
preparation and formulation procedures to produce and stabilize
amorphous pharmaceuticals. Readers will thus gain a well-funded
understanding and find a multi-faceted discussion of the properties
and advantages of amorphous drugs and of the challenges in
producing and stabilizing them. The book is an ideal source of
information for researchers and students as well as professionals
engaged in research and development of amorphous pharmaceutical
products.
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