Label-free biosensors are devices that use biological or chemical
receptors to detect analytes (molecules) in a sample. They give
detailed information on the selectivity, affinity, and, in many
cases, also the binding kinetics and thermodynamics of an
interaction. Although they can be powerful tools in the hands of a
skilled user, there is often a lack of knowledge of the best
methods for using label-free assays to screen for biologically
active molecules and accurately and precisely characterize
molecular recognition events. This book reviews both established
and newer label-free techniques and is intended to give both the
expert user and the general reader interested in the technologies
and applications behind label-free an insight into the field from
expert opinion leaders and practitioners of the technologies. Most
importantly, chapters contain worked examples from leaders in the
field that take the reader through the basics of experimental
design, setup, assay development, and data analysis.
General
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