Now with a new afterword covering the months-long landmark trials of Elizabeth Holmes and Sunny Balwani. ‘I couldn’t put down this thriller . . . the perfect book to read by the fire this winter.’ Bill Gates Winner of the Financial Times/McKinsey Business Book of the Year Award 2018 The riveting true story of the breathtaking rise and shocking collapse of Theranos, the multibillion-dollar biotech startup founded by Elizabeth Holmes, by the prize-winning journalist who first broke the story and pursued it to the end, despite pressure from its charismatic CEO and threats by her lawyers. In 2014, Theranos founder and CEO Elizabeth Holmes was widely seen as the female Steve Jobs: a brilliant Stanford dropout whose startup ‘unicorn’ promised to revolutionize the medical industry with a machine that would make blood testing significantly faster and easier. Backed by investors such as Larry Ellison and Tim Draper, Theranos sold shares in a fundraising round that valued the company at more than $9 billion, putting Holmes’s worth at an estimated $4.7 billion. There was just one problem: the technology didn’t work. In Bad Blood, John Carreyrou tells the riveting story of the biggest corporate fraud since Enron, a tale of ambition and hubris set amid the bold promises of Silicon Valley. ‘Chilling . . . Reads like a West Coast version of All the President’s Men.’ New York Times Book Review

IN "THE ANTIDOTE," Barry Werth draws upon unprecedented inside reporting spanning more than two decades to provide a groundbreaking closeup of the upstart pharmaceutical company Vertex and the ferocious but indispensable world of Big Pharma that it inhabits.
In 1989, the charismatic Joshua Boger left Merck, then America's most admired business, to found a drug company that would challenge industry giants and transform health care. Werth described the company's tumultuous early days during the AIDS crisis in "The Billion-Dollar Molecule," a celebrated classic of science and business journalism. Now he returns to tell a riveting story of Vertex's bold endurance and eventual success.
The $325 billion-a-year pharmaceutical business is America's toughest and one of its most profitable. It's riskier and more rigorous at just about every stage than any other business, from the towering biological uncertainties inherent in its mission to treat disease; to the 30-to-1 failure rate in bringing out a successful medicine even after a molecule clears all the hurdles to get to human testing; to the multibillion-dollar cost of ramping up a successful product; to operating in the world's most regulated industry, matched only by nuclear power.
Werth captures the full scope of Vertex's twentyfive- year drive to deliver breakthrough medicines. At a time when America struggles to maintain its innovative edge, "The Antidote" is a powerful inside look at one of the most intriguing and important business stories of recent decades.

The riveting true story of John and Aileen Crowley's race to find a cure for Pompe disease that inspired the movie Extraordinary Measures

With three beautiful children, a new house, and financial security, John and Aileen Crowley were on top of the world--until their two youngest children, fifteen-month-old Megan and five-month-old Patrick, were diagnosed with Pompe disease and given only months to live. Refusing to accept a death sentence, John quit his financial consultant job and invested his life savings in a biotechnology start-up to research the disease and find a cure. Battling scientific setbacks, conflict of interest accusations, and business troubles, John and Aileen would be tested to their limits as they valiantly fought, and succeeded, in finding revolutionary new treatment for the disease--offering hope to Megan, Patrick, and the many children and families affected by Pompe disease around the world.

The inspiration for the captivating film Extraordinary Measures, starring Brendan Fraser and Harrison Ford, The Cure is a remarkable true story of cutting-edge science, business acumen and daring, and one family's indomitable spirit.

The depletion of fossil fuels is a major issue in energy generation; hence, biomass and renewable energy sources, especially bioenergy, are the solution. The dependence on bioenergy has many benefits to mitigate environmental pollution. It is imperative that the global society adopts these alternative, sustainable energy sources in order to mitigate the constant growth of climate change. Biomass and Bioenergy Solutions for Climate Change Mitigation and Sustainability highlights the challenges of energy conservation and current scenarios of existing fossil fuel uses along with pollution potential of burning fossil fuel. It further promotes the inventory, assessment, and use of biomass, pollution control, and techniques. This book provides the solution for climate change, mitigation, and sustainability. Covering topics such as biofuel policies, economic considerations, and microalgae biofuels, this premier reference source is an essential resource for environmental scientists, environmental engineers, government officials, business leaders, politicians, librarians, students and faculty of higher education, researchers, and academicians.

For centuries, Chinese medicinal materials have been used for therapeutic purposes. Chinese medicinal materials are traditionally identified by their organoleptic characteristics, such as the texture or the odor. With the advancement of DNA technology, a molecular approach has become an important tool to complement organoleptic, morphological, anatomical and chemical techniques for the authentication and quality assurance of Chinese medicinal materials.In 2002, the authors published Authentication of Chinese Medicinal Materials by DNA Technology which is the first international reference in this field. After 20 years, this new edition updates the various useful techniques and describes the new techniques developed for molecular authentication. The procedures of each DNA technique are provided in detail for 'step-by-step' experiments.This book is divided into 5 parts with 18 chapters. Part I reviews the current status of molecular authentication and introduces a wide range of DNA techniques. Part II lists the experimental procedures for molecular authentication. Part III describes the DNA fingerprinting-based techniques. Part IV describes the DNA sequencing-based techniques. Finally, Part V provides an account on the recent advancement in molecular authentication, including guidelines for setting up a proper DNA laboratory and concluding remarks.

Biomaterials are advanced materials that garner interdisciplinary research. Wastewater pollution causes many adverse effects on human health and the environment. In order to rectify this, biomaterials and other nanomaterials have been utilized as photocatalysts against environmental waste. In this book, biomaterials are highlighted as a promising material for waste management, as biomaterials are cost-effective, eco-friendly and closer to nature.