Nanomaterials in the Battle Against Pathogens and Disease Vectors presents an overview of the use of nanotechnology to mitigate pathogens of concern, and is the first book to discuss applications of nanotechnology in the fight against all three major domains of disease-causing pathogens. Bacteria, viruses, and parasites constitute the list of emerging and re-emerging pathogens of high priority. Nanotechnology has proven to be a groundbreaking success in the elimination, targeted toxicity, precise immunogenicity, diagnosis, and imaging of these major pathogens and disease vectors. This text discusses basic concepts and advanced applications for bacteria, viruses, and parasites. It describes the use of metallic and non-metallic nanoparticles and nanotoxicity, as well as presents future applications of nanotechnology in biological applications. This work is ideal for engineers and scientists across the interdisciplinary fields of materials science, biomedical engineering, biotechnology, and others concerned with mitigating the risk and effect of pathogens.

Stresses the Potential Applications of Biosurfactants in Various Industries Environmental concerns and a demand for sustainable chemical production have become important issues in recent years. As a result, microbial biosurfactant-producing systems are gaining momentum as potential replacements for chemical surfactants. Biosurfactants: Production and Utilization-Processes, Technologies, and Economics explores the production, utilization, and industrial/economic use of biosurfactants in modern biotechnology. This book represents comprehensive material developed by contemporary experts in the field. Focusing on research and developments within the last 20 years, it highlights relevant changes in the industry. It provides a detailed account of the current applications of biosurfactants, considers the potential for further environmental, biological, and industrial applications, and concentrates on surfactants and organisms with possibilities for future use. Emphasizes Process Scale-Up and Commercialization Factoring in the industrial application of biosurfactant production based on renewable resources, the book determines how biosurfactants can enhance or replace the properties of chemically synthesized surface-active agents. It discusses moving beyond the laboratory scale of research and development and on to the industrial scale of commercial interest. The book consists of 17 chapters and features expert authors discussing topics that include: Understanding the regulatory processes controlling the production of biosurfactants Strategies for feasible commercial biosurfactant production Examples of cost analysis based on published information The viability of industrial applications in food, cosmetics, and pharmaceuticals Patents for future trends Biosurfactants: Production and Utilization-Processes, Technologies, and Economics contains special sections devoted to the overview and evaluation of specific patents relating to biosurfactants, and methods for production of biosurfactants on a laboratory and industrial/commercial scale. It also presents novel and proven applications for biosurfactants from a number of biotechnology laboratories and research facilities around the world. In addition, it introduces the reader to a variety of real-world industry techniques readily applicable for practical use.

Physical oncology has the potential to revolutionize cancer research and treatment. The fundamental rationale behind this approach is that physical processes, such as transport mechanisms for drug molecules within tissue and forces exchanged by cancer cells with tissue, may play an equally important role as biological processes in influencing progression and treatment outcome. This book introduces the emerging field of physical oncology to a general audience, with a focus on recent breakthroughs that help in the design and discovery of more effective cancer treatments. It describes how novel mathematical models of physical transport processes incorporate patient tissue and imaging data routinely produced in the clinic to predict the efficacy of many cancer treatment approaches, including chemotherapy and radiation therapy. By helping to identify which therapies would be most beneficial for an individual patient, and quantifying their effects prior to actual implementation in the clinic, physical oncology allows doctors to design treatment regimens customized to each patient's clinical needs, significantly altering the current clinical approach to cancer treatment and improving the outcomes for patients.

This new volume, Natural Polymers for Pharmaceutical Applications, Volume 1: Plant-Derived Polymers, presents some of the latest research on the applications of natural polymers in drug delivery and therapeutics for healthcare benefits. Polymers and their applications from several plants are discussed in depth, including tamarind gum, gum Arabic, natural carbohydrate polymer gum tragacanth, pectin, guar gum and its derivatives, locust bean gum, sterculia gum, okra gum, and others. The use of the polymers derived from plants as potential pharmaceutical excipients is expanding day by day because of their stability in the biological system, drug-releasing capability, drug-targeting abilities, as well as their bioavailability.

Many polymers derived from various marine sources and microorganisms possess some important biological properties such as biocompatibility, biodegradability, and bioadhesivity that make them attractive as pharmaceutical excipients in various pharmaceutical dosage forms. Moreover, these polymers can be modified physically and/or chemically to improve their biomaterial properties. In this volume, Natural Polymers for Pharmaceutical Applications, Volume 2: Marine- and Microbiologically Derived Polymers, looks at how these polymers have been explored and exploited for pharmaceutical uses, such as in tablets, microparticles, nanoparticles, ophthalmic preparations, gels, emulsions, suspensions, etc. Some commonly used marine- and microbiologically derived polymers used as pharmaceutical excipients include alginates, agar-agar, gellan gum, carrageenan; chitosan, xanthan gum, and others. The book focuses on important recent advances from experts around the world on marine-derived polysaccharides and pharmaceutical applications of alginates, agar-agar, gellan gum, carrageenan, chitosan derivatives, xanthan gum.

In recent years, many animal-derived polymers have emerged as an attractive category of naturally derived polymers because of their advantageous physicochemical, chemical, and biological properties. The important biological properties of these natural polymers derived from animals are biocompatibility and biodegradation. These polymers are generally composed of repeated units of amino acids. Moreover, these polymers can be modified physically and/or chemically to improve their biomaterial properties. Natural Polymers for Pharmaceutical Applications, Volume 3: Animal-Derived Polymers looks at how these polymers can be exploited as pharmaceutical excipients in various pharmaceutical dosage forms, like microparticles, nanoparticles, ophthalmic preparations, gels, implants, etc. The commonly used animal-derived polymers used as pharmaceutical excipients are hyaluronic acid (hyaluronan), albumin, collagen, gelatin, chondroitin, etc.

This new volume provides an abundance of information on new biomedical applications being used today. The book covers a wide range of concepts and technologies, discussing such modern technological methods as the Internet of Things, e-pills, biomedical sensors, support vector machines, wireless devices, image and signal processing in e-health, and machine learning. It also includes a discussion on software implementation for the devices used in biomedical applications. The different types of antennas, including antennas using RF energy harvesting for biomedical applications, are covered as well.

Provides information about the different surfactants. Describes constraints in production and novel production strategies. Includes application oriented aspects of biosurfactants in various fields such as agriculture, Environmental, Pharmaceutical, and Food industry. Authored by experts in the field of biosurfactants.

An introduction to the Central Dogma of molecular biology and information flow in biological systems. A systematic overview of the methods for generating gene expression data. Background knowledge on statistical modeling and machine learning techniques. Detailed methodology of analyzing gene expression data with an example case study. Clustering methods for finding co-expression patterns from microarray, bulkRNA and scRNA data. A large number of practical tools, systems and repositories that are useful for computational biologists to create, analyze and validate biologically relevant gene expression patterns. Suitable for multi-disciplinary researchers and practitioners in computer science and biological sciences.

This fascinating study describes efforts to define and protect traditional knowledge and the associated issues of access to genetic resources, from the negotiation of the Convention on Biological Diversity to The Declaration on the Rights of Indigenous Peoples and the Nagoya Protocol. Drawing on the expertise of local specialists from around the globe, the chapters judiciously mix theory and empirical evidence to provide a deep and convincing understanding of traditional knowledge, innovation, access to genetic resources, and benefit sharing. Because traditional knowledge was understood in early negotiations to be subject to a property rights framework, these often became bogged down due to differing views on the rights involved. New models, developed around the notion of distributive justice and self-determination, are now gaining favor. This book suggests - through a discussion of theory and contemporary case studies from Brazil, India, Kenya and Canada - that a focus on distributive justice best advances the interests of indigenous peoples while also fostering scientific innovation in both developed and developing countries. Comprehensive as well as nuanced, Genetic Resources and Traditional Knowledge will be of great interest to scholars and students of law, political science, anthropology and geography. National and international policy makers and those interested in the environment, indigenous peoples' rights and innovation will find the book an enlightening resource. Contributors: T. Bubela, J. Carbone, R. Crookshanks, L. DeBusschere, G. Dutfield, E.R. Gold, D.S. Hik, A. Kumbamu, C. Lawson, C. Metcalf, S. Nickels, K. Nnadozie, P.W.B. Phillips, E.B. Rodrigues Jr, T. Williams, S. Zhang

The average person produces about four hundred pounds of excrement a year. More than seven billion people live on this planet. Holy crap! Because of the diseases it spreads, we have learned to distance ourselves from our waste, but the long line of engineering marvels we've created to do so-from Roman sewage systems and medieval latrines to the immense, computerized treatment plants we use today-has also done considerable damage to the earth's ecology. Now scientists tell us: we've been wasting our waste. When recycled correctly, this resource, cheap and widely available, can be converted into a sustainable energy source, act as an organic fertilizer, provide effective medicinal therapy for antibiotic-resistant bacterial infection, and much more. In clear and engaging prose that draws on her extensive research and interviews, Lina Zeldovich documents the massive redistribution of nutrients and sanitation inequities across the globe. She profiles the pioneers of poop upcycling, from startups in African villages to innovators in American cities that convert sewage into fertilizer, biogas, crude oil, and even life-saving medicine. She breaks taboos surrounding sewage disposal and shows how hygienic waste repurposing can help battle climate change, reduce acid rain, and eliminate toxic algal blooms. Ultimately, she implores us to use our innate organic power for the greater good. Don't just sit there and let it go to waste.

Basic curiosity-driven biomedical science has delivered many of today's most significant medical advances. This book provides clearly explained examples from recent biomedical history and includes convincing arguments for sustaining a robust portfolio of basic research. Intended as an engaging read, which will delight undergraduate and graduate students, as well as scientific researchers, it is full-throated advocacy of basic science. Illustrations and examples include the discoveries of penicillin and insulin, and the breakthrough elucidation of the genetic code. Providing both compelling rationale in support of basic science, and a fascinating look through the history of modern biomedical research, this book highlights with stirring examples why basic biomedical research is so important, and how so many key advances in medicine are derived from basic research. The book also offers a rationale for scientific inquiry and a broader understanding of the history of modern biomedical research missing from today's classrooms. Key Features 1) Provides clear explanations of great scientific discoveries 2) Illustrates connections between basic research findings and modern medicine 3) Includes compelling graphics/diagrams/illustrations 4) Accessible to the general public 5) Offers background for more specialized readers, including researchers as well as those with advanced degrees. Related Titles Staddon, J. Scientific Method: How Science Works, Fails to Work, and Pretends to Work (ISBN 978-1-1382-9536-0) Helliwell, J. R. Skills for Scientific Life (ISBN 978-1-4987-6875-7) MacRitchie, F. Scientific Research as a Career (ISBN 978-1-4398-6965-9)

To succeed in the lab, it is crucial to be comfortable with the math calculations that are part of everyday work. This accessible introduction to common laboratory techniques focuses on the basics, helping even readers with good math skills to practice the most frequently encountered types of problems. Basic Laboratory Calculations for Biotechnology, Second Edition discusses very common laboratory problems, all applied to real situations. It explores multiple strategies for solving problems for a better understanding of the underlying math. Primarily organized around laboratory applications, the book begins with more general topics and moves into more specific biotechnology laboratory techniques at the end. This book features hundreds of practice problems, all with solutions and many with boxed, complete explanations; plus hundreds of "story problems" relating to real situations in the lab. Additional features include: Discusses common laboratory problems with all material applied to real situations Presents multiple strategies for solving problems help students to better understand the underlying math Provides hundreds of practice problems and their solutions Enables students to complete the material in a self-paced course structure with little teacher assistance Includes hundreds of "story problems"that relate to real situations encountered in the laboratory

Explores how antiviral nanomaterials can be used in developing targeted drug delivery practices and enable pharmaceutical industries to reformulate available drugs on market Covers immunization, imaging, and drug delivery and features various case studies on managing viral diseases Addresses synthesis protocols and recent developments by performing physicochemistry on virion substrate, hybrid viral networks, and multilayered arrays thus enabling R&D experts to study and successfully instigate cutting-edge technologies unique to viruses Discusses current and near future applications of antiviral nanomaterials and their activity in drug delivery systems Describes the role of nanotechnology in prevention, detection, and treatment of COVID-19 Investigates the role of antiviral nanodrugs play in human and animal body systems and in major viral disease types.

- Provides updated and detailed information about bioinformatics for human genomics research - Brings information from multiple areas of bioinformatics in one place - Facilitates application of key computational methods in human genomics research

Nanomedicine, a scientific branch of nanotechnology that operates on the same scale as biology, offers the possibility of influencing the healing process from inside of the body by manipulating the matter at cellular or molecular levels. Throughout this book, current healing approaches based on this revolutionary new technology are summarized from a scientific assessment. The aim of the authors is to give, through select examples, a deep insight to nanotechnology status and the great progress that its rigorous application will bring to human health. The authors' commitment is to broaden the vision of health professionals who will eventually be the future users of this knowledge.

Bio-butanol has gained wide recognition globally as an advanced biofuel, which can be used directly as a substitute for gasoline in internal combustion engines. This book provides readers with an in-depth knowledge of the various aspects and steps involved in butanol production. Further, the current global status, history, various technologies adopted for butanol production from different feedstocks, and the role of microorganisms in the production process are also covered. The book has 12 chapters, with each chapter dedicated to covering various aspects of butanol, from production to applications.

This book 'Extremophiles: Wastewater and Algal Biorefinery' explores the potential of extremophiles/extremotolerant organisms in wastewater treatment, biorefining of algal biomass and in the treatment of industrial waste effluent. The book provides a holistic overview about the current status of extremophiles in waste water treatment and various industrial processes. The chapters comprehensively cover the scientific and research findings on various industrial applications of extremophiles such as biofuels, extremozymes, electricity generation, biofilms, microbial corrosion and waste water treatment etc. This book is an integrated source of literature for the scientists, engineers, academicians, and students working in the area of extremophiles, microbial technology and biorefinery.

Explores planning for biogas plants as a pre-requisite to develop a functional plant balancing energy production and consumption Gives out detailed provision of the types of substances that are and can be used for biogas production covering animal wastes, municipal and industrial wastes Provides knowledge for aspiring biogas producers as well as decision makers, specifically in the context of Nigeria Covers use of digestrate for anaerobic digestion as a waste treatment method and on the input (feedstock) to the biogas plant Compares carbon dioxide emissions from biogas plants with fossil fuel plants

Biomass for Bioenergy and Biomaterials presents an overview of recent studies developed specifically for lignocellulose-based production of biofuels, biochemicals, and functional materials. The emphasis is on using sustainable chemistry and engineering to develop innovative materials and fuels for practical applications. Technological strategies for the physical processing or biological conversion of biomass for material production are also presented. FEATURES Offers a comprehensive view of biomass processing, biofuel production, life cycle assessment, techno-economic analysis, and biochemical and biomaterial production Presents details of innovative strategies to pretreat biomass Helps readers understand the underlying metabolic pathways and identify the best engineering strategies for their native strain Highlights different strategies to make biomaterials from biomass Provides insight into the potential economic viability of the biomass-based process This book serves as an ideal reference for academic researchers and engineers working with renewable natural materials, the biorefining of lignocellulose, and biofuels. It can also be used as a comprehensive reference source for university students in metabolic, chemical, and environmental engineering.

Introduces an approach to ethical decision making based on treating data as clients Compares the ethics of three professions; engineering, medicine and bioengineering Provides five moral theories to choose from for evaluating ethical decisions, and includes a procedure for applying them to moral analysis, and application of the procedure to example cases. Explains the process of developing a medical product under FDA regulation Explores the role of lawyers in product development, including intellectual property protection Examines a range of ethical cases, from the historical Tuskegee autonomy case to the modern CRISPR-Cas9 patent case.

The need for exploration, conservation, and sustainable utilization of bioresources is undeniable for the survival and growth of mankind. This new book throws light on new and recent research on and development of effective strategies for sustainable utilization of bioresources using modern tools and techniques to help meet this challenge. This volume addresses the utilization of bioresources in therapeutics, in biofuel, in agriculture, and in environmental protection. Beginning with the diverse potential applications of bioresources in food, medicine, and cosmetics, the volume goes on to address the various different underutilized bioresources and their sustainable uses. It discusses important advances in biofuel and patents that highlight recent developments that address the energy crises and the continuously fluctuating cost of petroleum. It explores new renewable energy sources from bioresources and their sustainable utilization in the bioenergy and biofuel industry. Several chapters focus on the sustainable utilization of bioresources in the agricultural sector. The volume considers that developing countries have huge agricultural resources that could be employed for production of value-added byproducts for the sustainable development of a bio-based economy. The book discusses efficient use of underexploited natural bioresources, new chemical approaches for the generation of novel biochemicals, and the applications of genetics approaches for bioresource conservation and production of value-added products. Further, strategies for the production of biopesticides utilizing bioresources are also discussed.

The over-riding premise for biotechnology in this book is bringing novel products to market to substantially advance patient care and disease mitigation. Biotechnology, over its relatively brief existence of 40 years, has experienced a mercurial growth. The vast educational need for biotechnology information in this rapidly burgeoning field is a basic rationale here. However a more prominent underpinning is that, bringing biotech products to market for patient care involves success in the following four areas of engagement simultaneously - scientific advances for healthcare technologies, novel and varied products for untreated diseases, regulatory authorities, and biotech companies. Features Comprehensive coverage of biotechnology science topics used in development and manufacturing Addresses all the scientific technologies within biotechnology responsible for products on the market and the pipeline Presents business issues such as marketing and sales of the products, as well as companies engaged, and how biotech business has evolved

Since synthetic plastics derived from fossil resources are mostly non-biodegradable, many academic and industrial researchers have shifted their attention toward bio-based materials, which are more eco-friendly. Bio-Based Composites for High-Performance Materials: From Strategy to Industrial Application provides an overview of the state-of-art in bio-based composites. The book integrates knowledge from various disciplines including plant science, materials science, polymer chemistry, chemical engineering, and nanotechnology. It discusses the raw materials used in bio-based composites, basic design principles, properties, applications, and life cycle assessments. The book also presents a strategic and policy-oriented view of these composites and considers the costs of retrofitting existing chemical production plants for bio-based composite manufacture. It is a definitive resource on bio-composites for academics, regulatory agencies, research and development communities, and industries worldwide.

Presents in-depth kinetics analysis Features well developed sections on the major topics of catalysts, kinetics, reactor design, and modeling Includes a fully worked out example Offers end of chapter problems and a solutions manual for adopting professors