Microbial Biotechnology in Food and Health Science, volume one in the Applied Biotechnology Reviews series, offers two unique sections within the theme of genomics and bioprocessing and the bioengineering of microorganisms in the role of food science and human health. This volume provides review articles as the basis supporting biotechnological research useful to a wide scope of research initiatives. Important relevant information on genomics, proteomics and metabolomics are included as well as the emerging interdisciplinary area of synthetic biology which enables the metabolic engineering of microorganisms to produce pharmaceuticals. Applied Biotechnology Reviews is a series aimed at bringing all aspects of biotechnology as it is applied to food science - from agriculture through product processing into focus through topical volumes. Each volume will cover a relevant application approach in industrial biotechnology.

Cosmic Genetic Evolution, Volume 106 in the Advances in Genetics series, highlights new advances in the field, with this new volume presenting interesting chapters on Panspermia, Cometary Panspermia and Origin of Life, The Efficient Lamarckian Spread of Life in the Cosmos, The Sociology of Science and Generality of the DNA/RNA/Protein Paradigm Throughout the Cosmos, The Mutagenic Source and Power of Our Own Evolution, Origin of New Emergent Coronavirus and Candida Fungal Diseases - Terrestrial or Cosmic?, and Future Prospects for Investigation -The Near-Earth Neighborhood and Beyond.

3D Printing in Medicine and Surgery: Applications in Healthcare is an advanced book on surgical and enhanced medical applications that can be achieved with 3D printing. It is an essential handbook for medical practitioners, giving access to a range of practical methods, while also focusing on applied knowledge. This comprehensive resource features practical experiments and processes for preparing 3D printable materials. Early chapters cover foundational knowledge and background reading, while later chapters discuss and review the current technologies used to engineer specific tissue types, experiments and methods, medical approaches and the challenges that lie ahead for future research. The book is an indispensable reference guide to the various methods used by current medical practitioners working at the forefront of 3D printing applications in medicine.

New and Future Developments in Microbial Biotechnology and Bioengineering: Recent Advances in Application of Fungi and Fungal Metabolites: Applications in Healthcare presents an account of recent development and applied aspects of fungi and its metabolites in the healthcare sector. Chapters are written by eminent researchers, emphasizing the incredible role of fungi and its metabolites in the field of medicine. This book offers reference material to all mycologists working on the exploration and usage of medicinal aspects of fungi and fungal metabolites.

Controlled Release Fertilizers for Sustainable Agriculture provides a comprehensive examination of precision fertilizer applications using the 4-R approach-the right amount of fertilizer at the right time to the right plant at the correct stage of plant growth. This volume consolidates detailed information on each aspect of controlled release fertilizers, including up-to-date literature citations, the current market for controlled release fertilizers and patents. Presenting the tremendous advances in experimental and theoretical studies on sustainable agriculture and related areas, this book provides in-depth insight into state-of-the-art controlled release mechanisms of fertilizers, techniques, and their use in sustainable agriculture. Conventional release mechanisms have historically meant waste of fertilizers and the adverse effects of that waste on the environment. Controlled release delivery makes significant strides in enhancing fertilizer benefit to the target plant, while protecting the surrounding environment and increasing sustainability.

Plant Breeding and Cultivar Development features an optimal balance between classical and modern tools and techniques related to plant breeding. Written for a global audience and based on the extensive international experience of the authors, the book features pertinent examples from major and minor world crops. Advanced data analytics (machine learning), phenomics and artificial intelligence are explored in the book's 28 chapters that cover classical and modern plant breeding. By presenting these advancements in specific detail, private and public sector breeding programs will learn about new, effective and efficient implementation. The insights are clear enough that non-plant breeding majoring students will find it useful to learn about the subject, while advanced level students and researchers and practitioners will find practical examples that help them implement their work.

Advances in Applied Microbiology, Volume 112, continues the comprehensive reach of this widely read and authoritative review source in microbiology. Users will find invaluable references and information on a variety of areas. Chapters in this new release include discussions of Microbial mercury transformation: focus on molecules and functions, Peptidoglycan Biosynthesis, Clockwork microbial worlds , Molecular engineering to improve the levels of bioproducts from agricultural and forestry waste by filamentous fungi, Multi-species Biofilms for Resource Recovery from Wastewater, Evasion of host defenses by intracellular Staphylococcus aureus, A genomic analysis on stress-responses in C. glabrata and their relevance in pathogenesis and drug resistance, and more.

Inflammation and Natural Products brings together research in the area of the natural products and their anti-inflammatory action in medical, nutraceutical and food products, addressing specific chronic inflammatory diseases like cancer and the mechanistic aspects of the mode of action of some key natural products. Inflammation is a complicated process, driven by infection or injury or genetic changes, which results in triggering signalling cascades, activation of transcription factors, gene expression, increased levels of inflammatory enzymes, and release of various oxidants and pro-inflammatory molecules in inflammatory cells. Excessive oxidants and inflammatory mediators have a harmful effect on normal tissue, including toxicity, loss of barrier function, abnormal cell proliferation, inhibiting normal function of tissues and organs and finally leading to systemic disorders. The emerging development of natural product formulations utilizing the unique anti-inflammatory compounds such as polyphenols, polysaccharides, terpenes, fatty acids, proteins and several other bioactive components has shown notable successes. Inflammation and Natural Products: Recent Development and Current Status provides a comprehensive resource, ranging from detailed explanation on inflammation to molecular docking strategies for naturally occurring compounds with anti-inflammatory activity. It is useful for graduate students, academic and professionals in the fields of pharmaceutical and medical sciences and specialists from natural product-related industries.

Advanced and Modern Approaches for Drug Delivery explores novel approaches currently used for drug delivery, including the must up-to-date techniques and technology. The approaches discussed allow pharmaceutical scientists to design effective drug delivery systems or devices for the management and treatment of numerous diseases and conditions. Detailed information on a wide variety of subjects, including dendrimers, lipid nanostructures, solid lipid nanoparticles, stimuli-responsive smart systems, self-assembled protein-drug nanoparticles, nanoconjugate formulations, nanofibers, iontophoretic systems, microneedle systems, ultra-sound triggered systems, targeted carrier-based intracellular delivery systems, resealed erythrocyte-based systems, 3 D-printing tool, site-specific monoclonal antibodies, and bio-inspired systems are all comprehensively discussed. With contributions from those in academia and industry, this book is an excellent reference for all those needing to understand drug delivery systems.

Advances in Applied Microbiology, Volume 113, continues the comprehensive reach of this widely read and authoritative review source in microbiology. Users will find invaluable references and information on a variety of areas relating to the topic, with this release focusing on Gaps in the Assortment of Rapid Assays for Microorganisms of Interest to the Dairy Industry, Metal reduction and corrosion by bacterial biofilms, The microbiology of red brines, Clostridium thermocellum: a microbial platform for high-value chemical production from lignocellulose, and The zincophore system in pathogenic yeasts.

New and Future Developments in Microbial Biotechnology and Bioengineering: Recent Developments in Trichoderma Research covers topics on-Trichoderma biodiversity, strain improvement and related researches in bioprocess technology, chemical engineering, bioremediation process, secondary metabolite production, Protein production, plant disease resistance and biocontrol technology. This book includes unique compilations of different chapters with emerging issues in the area of Trichoderma research and its related importance in the Biochemical-Industry-Agri-Food sector.

Handbook of Analytical Quality by Design addresses the steps involved in analytical method development and validation in an effort to avoid quality crises in later stages. The AQbD approach significantly enhances method performance and robustness which are crucial during inter-laboratory studies and also affect the analytical lifecycle of the developed method. Sections cover sample preparation problems and the usefulness of the QbD concept involving Quality Risk Management (QRM), Design of Experiments (DoE) and Multivariate (MVT) Statistical Approaches to solve by optimizing the developed method, along with validation for different techniques like HPLC, UPLC, UFLC, LC-MS and electrophoresis. This will be an ideal resource for graduate students and professionals working in the pharmaceutical industry, analytical chemistry, regulatory agencies, and those in related academic fields.

ODE/PDE Analysis of Antibiotic/Antimicrobial Resistance: Programming in R presents mathematical models for antibiotic/antimicrobial resistance based on ordinary and partial differential equations (ODE/PDEs). Sections cover the basic ODE model, the detailed PDE model that gives the spatiotemporal distribution of four dependent variable components, including susceptible bacteria population density, resistant bacteria population density, plasmid number, and antibiotic concentration. The computer-based implementation of the example models is presented through routines coded (programmed) in R, a quality, open-source scientific computing system that is readily available from the Internet. As such, formal mathematics is minimized and no theorems and proofs are required. The PDE analysis is based on the method of lines (MOL), an established general algorithm for PDEs that is implemented with finite differences. Routines are available from a download link so that the example models can be executed without having to first study numerical methods and computer coding. Routines can then be applied to variations and extensions of the antibiotic/antimicrobial models, such as changes in the ODE/PDE parameters (constants) and the form of the model equations.

Policy Issues in Genetically Modified Crops: A Global Perspective contains both theoretical and empirical evidence of a broad range of aspects of GM crop policies throughout the world. Emphasizing world agriculture production and ethics of GM crops, the book balances insights into the various discussions around the use of GM crops including soil health, effects on animals, environmental sustainability impact, and ethical issues. The book presents aspects of GM crop policies and prevailing controversies throughout the world, in 5 sections containing 23 chapters. Beginning with the discussion of the policies related to GM crops, the book dives deep into issues related to food insecurity, agricultural sustainability, food safety, and environmental risks. Section 5 also captures the recent advances in agricultural biotechnology encompassing research trends, the nano-biotech approach to plant genetic engineering, and other transformation techniques in crop development. The contributors of the book represent different backgrounds, providing a holistic overview of diverse approaches and perspectives. Policy Issues in Genetically Modified Crops: A Global Perspective is a valuable resource for researchers in agricultural policy and economics, agricultural biotechnology, soil science, genetic engineering, ethics, environmental management, sustainable development, and NGOs.

Digital Health: Mobile and Wearable Devices for Participatory Health Applications is a key reference for engineering and clinical professionals considering the development or implementation of mobile and wearable solutions in the healthcare domain. The book presents a comprehensive overview of devices and appropriateness for the respective applications. It also explores the ethical, privacy, and cybersecurity aspects inherent in networked and mobile technologies. It offers expert perspectives on various approaches to the implementation and integration of these devices and applications across all areas of healthcare. The book is designed with a multidisciplinary audience in mind; from software developers and biomedical engineers who are designing these devices to clinical professionals working with patients and engineers on device testing, human factors design, and user engagement/compliance.

Transhumanism is widely misunderstood, in part because the media have exaggerated current technologies and branded the movement as dangerous, leading many to believe that hybrid humans may soon walk among us and that immortality, achieved by means of mind-uploading, is imminent. In this essential and clarifying volume, Stefan Lorenz Sorgner debunks widespread myths about transhumanism and tackles the most pressing ethical issues in the debate over technologically assisted human enhancement. On Transhumanism is a vital primer on the subject, written by a world-renowned expert. In this book, Sorgner presents an overview of the movement's history, capably summarizing the twelve pillars of transhumanist discourse and explaining the great diversity of transhumanist responses to each individual topic. He highlights the urgent ethical challenges related to the latest technological developments, inventions, and innovations and compares the unique cultural standing of transhumanism to other cultural movements, placing it within the broader context of the Enlightenment, modernity, postmodernity, and the philosophical writings of Nietzsche. Engagingly written and translated and featuring an introduction for North American readers, this comprehensive overview of the cultural and philosophical movement of transhumanism will be required reading for students of posthumanist philosophy and for general audiences interested in learning about the transhumanist movement.

Biomaterials for 3D Tumor Modeling reviews the fundamentals and most relevant areas of the latest advances of research of 3D cancer models, focusing on biomaterials science, tissue engineering, drug delivery and screening aspects. The book reviews advanced fundamental topics, including the causes of cancer, existing cancer models, angiogenesis and inflammation during cancer progression, and metastasis in 3D biomaterials. Then, the most relevant biomaterials are reviewed, including methods for engineering and fabrication of biomaterials. 3D models for key biological systems and types of cancer are also discussed, including lung, liver, oral, prostate, pancreatic, ovarian, bone and pediatric cancer. This book is suitable for those working in the disciplines of materials science, biochemistry, genetics, molecular biology, drug delivery and regenerative medicine.

Storing Digital Binary Data into Cellular DNA demonstrates how current digital information storage systems have short longevity and limited capacity, also pointing out that their production and consumption of data exceeds supply. Author Rocky Termanini explains the DNA system and how it encodes vast amounts of data, then presents information on the emergence of DNA as a storage technology for the ever-growing stream of data being produced and consumed. The book will be of interest to a range of readers looking to understand this game-changing technology, including researchers in computer science, biomedical engineers, geneticists, physicians, clinicians, law enforcement and cybersecurity experts.

Wearable Bioelectronics presents the latest on physical and (bio)chemical sensing for wearable electronics. It covers the miniaturization of bioelectrodes and high-throughput biosensing platforms while also presenting a systemic approach for the development of electrochemical biosensors and bioelectronics for biomedical applications. The book addresses the fundamentals, materials, processes and devices for wearable bioelectronics, showcasing key applications, including device fabrication, manufacturing, and healthcare applications. Topics covered include self-powering wearable bioelectronics, electrochemical transducers, textile-based biosensors, epidermal electronics and other exciting applications.

Biotechnology in the Chemical Industry: Towards a Green and Sustainable Future focuses on achievements and prospects for biotechnology in sustainable production of goods and services, especially those that are derived at present mostly from the traditional chemical industry. It considers the future impact of industrial biotechnology and lays out the major research areas which must be addressed to move from a flourishing set of scientific disciplines to a major contributor to a successful future knowledge-based economy. The book focuses on the research needed to underpin three broad topics: biomass, bio-processes and bio-products, including bio-energy. Readers, including advanced students, researchers, industry professionals, academics, analysts, consultants, and anyone else interested, or involved in biotechnology will find this book very informative.

From Biofiltration to Promising Options in Gaseous Fluxes Biotreatment: Recent Developments, New Trends, Advances, and Opportunities provides an overview on the biological tools used for the treatment of the gaseous fluxes, with emphasis on traditional and perspective options, opening new horizons for research and implementation in practice. It is known that air pollution is an emergent global issue and a priority within the international environmental programs. Moreover, technologies based on biological methods are significantly contributing to the sustainable development concept. Thus this book provides tools for solving air pollution issues in a sustainable manner. These issues can be solved at different levels (e.g., "end-of-pipe" gaseous streams, indoor/outdoor air, closed environments), which can be approached by the different biotechniques presented in the book, from classical biofiltration techniques (part 1) to phytotreatment and microalgae-based techniques (part 2). Although all options have their particularities that make them special for certain applications, a special attention is drawn to the potential of the last one, which offers multiple possibilities for biomass valorization. Scientists from worldwide with relevant experience in their field have been contributed to the development of this book.

Biovalorisation of Wastes to Renewable Chemicals and Biofuels addresses advanced technologies for converting waste to biofuels and value-added products. Biovalorisation has several advantages over conventional bioremediation processes as it helps reduce the costs of bioprocesses. Examples are provided of several successfully commercialized technologies, giving insight into developing, potential processes for biovalorisation of different wastes. Different bioprocess strategies are discussed for valorising the wastes coming from the leather industry, olive oil industry, pulp and paper, winery, textile, and food industries, as well as aquaculture. A section on biorefinery for hydrocarbons and emerging contaminants is included to cover concepts on biodesulfurization of petroleum wastes, leaching of heavy metals from E - waste, and bioelectrochemical processes for CO2. Chapters on algal biorefinery are also included to focus on the technologies for conversion of CO2 sequestration and wastewater utilization. Biovalorisation of Wastes to Renewable Chemicals and Biofuels can be used as course material for graduate students in chemical engineering, chemistry, and biotechnology, and as a reference for industrial professionals and researchers who want to gain a basic understanding on the subject.

New and Future Developments in Microbial Biotechnology and Bioengineering: Microbial Biofilms is divided into three sections: microbial adhesion/biofilms in medical settings, microbial adhesion/biofilms in agriculture, and microbial adhesion/biofilm in the environment and industry. Chapters cover adhesion and biofilm formation by pathogenic microbes on tissue and on indwelling medical devices, including sections on human infections, microbial communication during biofilm mode of growth, host defense and antimicrobial resistance, and more. Other sections cover the biofilms of agriculturally important and environmental friendly microbes, including biofilm formation on plants, in soil, and in aquatic environments. Finally, the latest scientific research on microbial adhesion and biofilm formation in the environment and in industry is covered.

Handbook of Polymers in Medicine combines core concepts and advanced research on polymers, providing a better understanding of this class of materials in medicine. The book covers all aspects of medical polymers from characteristics and biocompatibility, to the diverse array of applications in medicine. Chapters cover an introduction to polymers in medicine and the challenges associated with biocompatibility in human tissue, polyurethane and supramolecular polymers and their specific applications in medicine, from tissue regeneration to orthopedic surgery and cancer therapeutics. This book offers an interdisciplinary approach that will appeal to researchers in a range of disciplines, including biomedical engineering, materials science, chemistry, pharmacology and translational medicine. The book will also make a useful reference for clinicians and those in medical fields who are interested in materials for medical applications, as well as R&D groups involved in medical device design.