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Books > Professional & Technical > Biochemical engineering > Biotechnology

Enzymes as Sensors, Volume 589 (Hardcover): Richard Thompson, Carol A. Fierke Enzymes as Sensors, Volume 589 (Hardcover)
Richard Thompson, Carol A. Fierke
R4,538 Discovery Miles 45 380 Ships in 10 - 15 working days

Enzymes as Sensors, Volume 589, the latest release in the Methods in Enzymology series, covers a variety of topics, including advances in genetically coded fluorescent sensors, enzymes as sensors, and bioapplications of electrochemical sensors and biosensors. Users will find a comprehensive discussion of timely topics that presents a micro-level delivery of specific content related to the study of enzymes in sensors. New to this edition are highly specialized chapters on integrated strategies for gaining a systems level view of dynamic signaling networks, sensitive protein detection and quantification in paper-based microfluidics for point-of-care, and microneedle enzyme sensor arrays for continuous in vivo monitoring. This state-of-the-art series is ideal for those interested in the latest information on enzymology, with this edition focusing on sensors and their role in enzymes.

Marine Enzymes Biotechnology: Production and Industrial Applications, Part II - Marine Organisms Producing Enzymes, Volume 79... Marine Enzymes Biotechnology: Production and Industrial Applications, Part II - Marine Organisms Producing Enzymes, Volume 79 (Hardcover)
Fidel Toldra; Volume editing by Se-Kwon Kim
R3,932 Discovery Miles 39 320 Ships in 10 - 15 working days

Marine Enzymes Biotechnology: Production and Industrial Applications, Part II - Marine Organisms Producing Enzymes provides a huge treasure trove of information on marine organisms. Nowadays, marine organisms are good candidates for enzymes production and have been recognized as a rich source of biological molecules that are of potential interest to various industries. Marine enzymes such as amylases, carboxymethylcellulases, proteases, chitinases, keratinases, xylanases, agarases, lipases, peroxidase and tyrosinases are widely used in the industry for the manufacture of pharmaceuticals, foods, beverages, and confectioneries, as well as in textile and leather processing, and in waste water treatment. The majority of the enzymes used in the industry are of microbial origin because microbial enzymes are relatively more stable than the corresponding enzymes derived from plants and animals.

Nanocomposites for Musculoskeletal Tissue Regeneration (Hardcover): Huinan Liu Nanocomposites for Musculoskeletal Tissue Regeneration (Hardcover)
Huinan Liu
R6,637 Discovery Miles 66 370 Ships in 10 - 15 working days

Nanocomposites for Musculoskeletal Tissue Regeneration discusses the advanced biomaterials scientists are exploring for use as tools to mimic the structure of musculoskeletal tissues. Bone and other musculoskeletal tissues naturally have a nanocomposite structure, therefore nanocomposites are ideally suited as a material for replacing and regenerating these natural tissues. In addition, biological properties such as biointegration and the ability to tailor and dope the materials make them highly desirable for musculoskeletal tissue regeneration.

Evidence-Based Validation of Herbal Medicine (Hardcover, UK ed.): Pulok K. Mukherjee Evidence-Based Validation of Herbal Medicine (Hardcover, UK ed.)
Pulok K. Mukherjee
R4,281 Discovery Miles 42 810 Ships in 10 - 15 working days

Evidence-Based Validation of Herbal Medicines brings together current thinking and practice in the areas of characterization and validation of natural products. This book reviews all aspects of evaluation and development of medicines from plant sources, including their cultivation, collection, phytochemical and phyto-pharmacological evaluation, and therapeutic potential. Emphasis is placed on describing the full range of evidence-based analytical and bio-analytical techniques used to characterize natural products, including -omic technologies, phyto-chemical analysis, hyphenated techniques, and many more.

Therapeutic Risk Management of Medicines (Hardcover, New): Stephen J. Mayall, Anjan Swapu Banerjee Therapeutic Risk Management of Medicines (Hardcover, New)
Stephen J. Mayall, Anjan Swapu Banerjee
R4,565 Discovery Miles 45 650 Ships in 10 - 15 working days

Therapeutic risk management of medicines is an authoritative and practical guide on developing, implementing and evaluating risk management plans for medicines globally. It explains how to assess risks and benefit-risk balance, design and roll out risk minimisation and pharmacovigilance activities, and interact effectively with key stakeholders.

A more systematic approach for managing the risks of medicines arose following a number of high-profile drug safety incidents and a need for better access to effective but potentially risky treatments. Regulatory requirements have evolved rapidly over the past decade. Risk management plans (RMPs) are mandatory for new medicinal products in the EU and a Risk Evaluation and Mitigation Strategy (REMS) is needed for certain drugs in the US.

This book is an easy-to-read resource that complements current regulatory guidance, by exploring key areas and practical implications in greater detail. It is structured into chapters encompassing a background to therapeutic risk management, strategies for developing RMPs, implementation of RMPs, and the continuing evolution of the risk management field.The topic is of critical importance not only to the pharmaceutical and biotechnology industries, but also regulators and healthcare policymakers.Some chapters feature contributions from selected industry experts.
An up-to-date practical guide on conceiving, designing, and implementing global therapeutic risk management plans for medicinesA number of useful frameworks are presented which add impact to RMPs (Risk Management Plans), together with regional specific information (European Union, United States, and Japan)Acomprehensive guide for performing risk management more effectively throughout a product s life-cycle"

Biomaterials for Cancer Therapeutics - Diagnosis, Prevention and Therapy (Hardcover, New): Kinam Park Biomaterials for Cancer Therapeutics - Diagnosis, Prevention and Therapy (Hardcover, New)
Kinam Park
R4,207 Discovery Miles 42 070 Ships in 10 - 15 working days

Cancer can affect people of all ages, and approximately one in three people are estimated to be diagnosed with cancer during their lifetime. Extensive research is being undertaken by many different institutions to explore potential new therapeutics, and biomaterials technology is now being developed to target, treat and prevent cancer. This unique book discusses the role and potential of biomaterials in treating this prevalent disease.
The first part of the book discusses the fundamentals of biomaterials for cancer therapeutics. Chapters in part two discuss synthetic vaccines, proteins and polymers for cancer therapeutics. Part three focusses on theranosis and drug delivery systems, whilst the final set of chapters look at biomaterial therapies and cancer cell interaction.
This extensive book provides a complete overview of the latest research into the potential of biomaterials for the diagnosis, therapy and prevention of cancer. Biomaterials for cancer therapeutics is an essential text for academics, scientists and researchers within the biomedical industry, and will also be of interest to clinicians with a research interest in cancer therapies and biomaterials.
A complete overview of the latest research into the potential of biomaterials for the diagnosis, therapy and prevention of cancerDiscusses the fundamentals of biomaterials for cancer therapeuticsDiscusses synthetic vaccines, proteins and polymers for cancer therapeutics

Lean Biomanufacturing - Creating Value through Innovative Bioprocessing Approaches (Hardcover, New): Nigel  J. Smart Lean Biomanufacturing - Creating Value through Innovative Bioprocessing Approaches (Hardcover, New)
Nigel J. Smart
R4,223 Discovery Miles 42 230 Ships in 10 - 15 working days

With decreasing profit margins, increasing cost pressures, growing regulatory compliance concerns, mounting pressure from generic drugs and increasing anxiety about the future of healthcare reimbursement, pharmaceutical manufacturers are now forced to re-examine and re-assess the way they have been doing things. In order to sustain profitability, these companies are looking to reduce waste (of all kinds), improve efficiency and increase productivity. Many of them are taking a closer look at lean manufacturing as a way to achieve these goals. Lean biomanufacturing re-visits lean principles and then applies them sympathetically - in a highly practical approach - to the specific needs of pharmaceutical processes, which present significantly different challenges to more mainstream manufacturing processes. A major goal of the book is to highlight those problems and issues that appear more specific or unique to biopharmaceutical manufacturing situations and to provide some insights into what challenges are the important ones to solve and what techniques, tools and mechanisms to employ to be successful.
Following an introduction to lean biomanufacturing, the book goes on to discuss lean technologies and methods applied in biomanufacturing. Later chapters cover the creation and implementation of the Transition Plan, issues facing the biopharmaceutical industry, creating a lean approach towards biopharmaceutical processes and the contribution of simulation models in developing these processes. The final chapter covers examples of new technology innovations which help facilitate lean biomanufacturing.
A focus on the issues associated with the application of lean principles to biomanufacturingPractical examples of factors which can affect biopharmaceutical processesCoverage of key factors which require integration to run an efficient biopharmaceutical process

Implantable Sensor Systems for Medical Applications (Hardcover, New): Andreas Inmann, Diana Hodgins Implantable Sensor Systems for Medical Applications (Hardcover, New)
Andreas Inmann, Diana Hodgins
R4,749 Discovery Miles 47 490 Ships in 10 - 15 working days

Implantable sensor systems offer great potential for enhanced medical care and improved quality of life, consequently leading to major investment in this exciting field. Implantable sensor systems for medical applications provides a wide-ranging overview of the core technologies, key challenges and main issues related to the development and use of these devices in a diverse range of medical applications.
Part one reviews the fundamentals of implantable systems, including materials and material-tissue interfaces, packaging and coatings, microassembly, electrode array design and fabrication, and the use of biofuel cells as sustainable power sources. Part two goes on to consider the challenges associated with implantable systems. Biocompatibility, sterilization considerations and the development of active implantable medical devices in a regulated environment are discussed, along with issues regarding data protection and patient privacy in medical sensor networks. Applications of implantable systems are then discussed in part three, beginning with Microelectromechanical systems (MEMS) for in-vivo applications before further exploration of tripolar interfaces for neural recording, sensors for motor neuroprostheses, implantable wireless body area networks and retina implants.
With its distinguished editors and international team of expert contributors, Implantable sensor systems for medical applications is a comprehensive guide for all those involved in the design, development and application of these life-changing technologies.
Provides a wide-ranging overview of the core technologies, key challenges and main issues related to the development and use of implantable sensor systems in a range of medical applicationsReviews the fundamentals of implantable systems, including materials and material-tissue interfaces, packaging and coatings, and microassemblyConsiders the challenges associated with implantable systems, including biocompatibility and sterilization

Diamond-Based Materials for Biomedical Applications (Hardcover, New): Roger Narayan Diamond-Based Materials for Biomedical Applications (Hardcover, New)
Roger Narayan
R3,788 Discovery Miles 37 880 Ships in 10 - 15 working days

Carbon is light-weight, strong, conductive and able to mimic natural materials within the body, making it ideal for many uses within biomedicine. Consequently a great deal of research and funding is being put into this interesting material with a view to increasing the variety of medical applications for which it is suitable. Diamond-based materials for biomedical applications presents readers with the fundamental principles and novel applications of this versatile material.
Part one provides a clear introduction to diamond based materials for medical applications. Functionalization of diamond particles and surfaces is discussed, followed by biotribology and biological behaviour of nanocrystalline diamond coatings, and blood compatibility of diamond-like carbon coatings. Part two then goes on to review biomedical applications of diamond based materials, beginning with nanostructured diamond coatings for orthopaedic applications. Topics explored include ultrananocrystalline diamond for neural and ophthalmological applications, nanodiamonds for drug delivery systems, and diamond nucleation and seeding techniques for tissue regeneration. Finally, the book concludes with a discussion of diamond materials for microfluidic devices.
With its distinguished editors and international team of expert contributors, Diamond-based materials for biomedical applications is an authoritative guide for all materials scientists, researchers, medical practitioners and academics investigating the properties and uses of diamond based materials in the biomedical environment.
Presents the fundamental principles and novel applications of this versatile materialDiscusses the functionalization of diamond particles and surfaces, biotribology and biological behaviour of nanocrystalinediamond coatings and blood compatibility of diamond-like carbon coatingsReviews nanostructured diamond coatings for orthopaedic coatings

Therapeutic Antibody Engineering - Current and Future Advances Driving the Strongest Growth Area in the Pharmaceutical Industry... Therapeutic Antibody Engineering - Current and Future Advances Driving the Strongest Growth Area in the Pharmaceutical Industry (Hardcover, New)
William R. Strohl, Lila M. Strohl
R6,033 R5,578 Discovery Miles 55 780 Save R455 (8%) Ships in 10 - 15 working days

The field of antibody engineering has become a vital and integral part of making new, improved next generation therapeutic monoclonal antibodies, of which there are currently more than 300 in clinical trials across several therapeutic areas. Therapeutic antibody engineering examines all aspects of engineering monoclonal antibodies and analyses the effect that various genetic engineering approaches will have on future candidates. Chapters in the first part of the book provide an introduction to monoclonal antibodies, their discovery and development and the fundamental technologies used in their production. Following chapters cover a number of specific issues relating to different aspects of antibody engineering, including variable chain engineering, targets and mechanisms of action, classes of antibody and the use of antibody fragments, among many other topics. The last part of the book examines development issues, the interaction of human IgGs with non-human systems, and cell line development, before a conclusion looking at future issues affecting the field of therapeutic antibody engineering.
Goes beyond the standard engineering issues covered by most books and delves into structure-function relationshipsIntegration of knowledge across all areas of antibody engineering, development, and marketingDiscusses how current and future genetic engineering of cell lines will pave the way for much higher productivity

Protein Folding in Silico - Protein Folding Versus Protein Structure Prediction (Hardcover, New): Irena Roterman-Konieczna Protein Folding in Silico - Protein Folding Versus Protein Structure Prediction (Hardcover, New)
Irena Roterman-Konieczna
R3,855 Discovery Miles 38 550 Ships in 10 - 15 working days

Protein folding is a process by which a protein structure assumes its functional shape of conformation, and has been the subject of research since the publication of the first software tool for protein structure prediction. Protein folding in silico approaches this issue by introducing an ab initio model that attempts to simulate as far as possible the folding process as it takes place in vivo, and attempts to construct a mechanistic model on the basis of the predictions made. The opening chapters discuss the early stage intermediate and late stage intermediate models, followed by a discussion of structural information that affects the interpretation of the folding process. The second half of the book covers a variety of topics including ligand binding site recognition, the "fuzzy oil drop" model and its use in simulation of the polypeptide chain, and misfolded proteins. The book ends with an overview of a number of other ab initio methods for protein structure predictions and some concluding remarks.
Discusses a range of ab initio models for protein structure predictionIntroduces a unique model based on experimental observationsDescribes various methods for the quantitative assessment of the presented models from the viewpoint of information theory

Developments in Tissue Engineered and Regenerative Medicine Products - A Practical Approach (Hardcover, New): Joydeep Basu,... Developments in Tissue Engineered and Regenerative Medicine Products - A Practical Approach (Hardcover, New)
Joydeep Basu, John W Ludlow
R4,038 Discovery Miles 40 380 Ships in 10 - 15 working days

Developments in tissue engineered and regenerative medicine products summarizes recent developments in tissue engineering and regenerative medicine with an emphasis on commercialization and product development. Features of current cell therapy and tissue engineered products which have facilitated successful commercialization are emphasized and roadblocks to successful product development are also highlighted. Preclinical and clinical testing of tissue engineered and regenerative medicine products, regulatory, quality control, manufacturing issues, as well as generating and securing intellectual property and freedom to operate considerations are presented. This book represents a complete 'how-to' manual for the development of tissue engineered and regenerative medicine products from conceptualization to clinical trial to manufacturing.
Addresses practical considerations for the field of tissue engineering and regenerative medicine from the perspective of the biotechnology industryWritten as a manual for tissue engineering and regenerative medicine product development applicable to the US and EUIllustrates pathway integration of science and business required for successful product development

Modelling and Analysis of Active Biopotential Signals in Healthcare, Volume 2 (Paperback): Varun Bajaj Modelling and Analysis of Active Biopotential Signals in Healthcare, Volume 2 (Paperback)
Varun Bajaj
R781 Discovery Miles 7 810 Ships in 10 - 15 working days
Magnesium-Based Nanocomposites (Paperback): Sankaranarayanan Seetharaman Magnesium-Based Nanocomposites (Paperback)
Sankaranarayanan Seetharaman
R763 Discovery Miles 7 630 Ships in 10 - 15 working days
Neurological Disorders and Imaging Physics, Volume 5 - Applications in dyslexia, epilepsy and Parkinson's (Paperback):... Neurological Disorders and Imaging Physics, Volume 5 - Applications in dyslexia, epilepsy and Parkinson's (Paperback)
Aymen El-Baz, Jasjit S. Suri
R768 Discovery Miles 7 680 Ships in 10 - 15 working days
Multiscale Modeling of Vascular Dynamics of Micro- and Nano-particles - Application to drug delivery system (Paperback): Huilin... Multiscale Modeling of Vascular Dynamics of Micro- and Nano-particles - Application to drug delivery system (Paperback)
Huilin Ye, Zhiqiang Shen, Ying Li
R750 Discovery Miles 7 500 Ships in 10 - 15 working days
Metabolic Maps - Pesticides, Environmentally Relevant Molecules and Biologically Active Molecules (Hardcover): Hiroyasu Aizawa Metabolic Maps - Pesticides, Environmentally Relevant Molecules and Biologically Active Molecules (Hardcover)
Hiroyasu Aizawa
R3,962 Discovery Miles 39 620 Ships in 10 - 15 working days

People working in development of drugs, pesticides, washing detergents, etc., are obliged by law to conduct analyses of the "metabolic pathways" or "maps" for the chemical compounds that they are using or proposing.
Everyone in these industries or carrying out research toward such products is therefore interested in having a reference on these compounds.
Key Features
* Covers literature relating to degradation and metabolic profiles of molecules
* Draws together the literature on degradation and metabolism patterns with that on diversified conditions of the environmental systems
* Indicates 3D chemical structures, predicted physico-chemical parameters, logP and the SMILES chemical notations of the parent compounds to assist scientists design the lead compounds for new discovery using computer-aided technology

Advances in DNA Sequence-Specific Agents, Volume 2 (Hardcover, UK ed.): J.B. Chaires Advances in DNA Sequence-Specific Agents, Volume 2 (Hardcover, UK ed.)
J.B. Chaires
R1,840 Discovery Miles 18 400 Ships in 10 - 15 working days

DNA sequence specificity is a sub-specialty in the general area of molecular recognition. This area includes macromolecular-molecular interactions (e.g., protein-DNA), oligomer-DNA interacitons (e.g., triple strands), and ligand-DNA interactions (e.g., drug-DNA). It is this latter group of DNA sequence specificity interactions that is the subject of Volumes 1 and 2 of "Advances in DNA Sequence Specific Agents." As was the case for Volume 1, Part A also covers methodology, but in Volume 2 we include calorimetric titrations, molecular modeling, X-ray crystallographic and NMR structural studies, and transcriptional assays. Part B also follows the same format as Volume 1 and describes the sequence specificities and covalent and noncovalent interactions of small ligands with DNA.
This volume is aimed in general at scientists who have an interest in deciphering the molecular mechanisms for sequence recognition of DNA. The methods have general applicability to small molecules as well as oligomers and proteins, while the examples provide general principles involved in sequence recognition.

Methods in Gene Technology, Volume 2 (Hardcover): JW Dale, P.G. Sanders Methods in Gene Technology, Volume 2 (Hardcover)
JW Dale, P.G. Sanders
R1,218 Discovery Miles 12 180 Ships in 10 - 15 working days

Gene probes, whether RNA or DNA, have played a central role in the rapid development of molecular biology. The wide variety of applications is matched by a considerable diversity in the methods used for generating probes, a complete account of which would be very difficult to make. Instead, this second volume in the series combines a selection of newer gene probe procedures with a review of the most important established methods, together with some examples of the ways in which gene probes can be applied. In doing so, the book aims to act not only as an introductory manual for newcomers to the field, but also as a means of broadening the horizons of existing researchers.

Introduction to Pharmaceutical Biotechnology, Volume 1 - Basic techniques and concepts (Paperback): Saurabh Bhatia, Divakar Goli Introduction to Pharmaceutical Biotechnology, Volume 1 - Basic techniques and concepts (Paperback)
Saurabh Bhatia, Divakar Goli
R771 Discovery Miles 7 710 Ships in 10 - 15 working days
The Origins of Evolutionary Innovations - A Theory of Transformative Change in Living Systems (Hardcover, New): Andreas Wagner The Origins of Evolutionary Innovations - A Theory of Transformative Change in Living Systems (Hardcover, New)
Andreas Wagner
R4,853 Discovery Miles 48 530 Ships in 10 - 15 working days

The history of life is a nearly four billion year old story of transformative change. This change ranges from dramatic macroscopic innovations such as the evolution of wings or eyes, to a myriad of molecular changes that form the basis of macroscopic innovations. We are familiar with many examples of innovations (qualitatively new phenotypes that can provide a critical advantage) but have no systematic understanding of the principles that allow organisms to innovate. This book proposes several such principles as the basis of a theory of innovation, integrating recent knowledge about complex molecular phenotypes with more traditional Darwinian thinking. Central to the book are genotype networks: vast sets of connected genotypes that exist in metabolism and regulatory circuitry, as well as in protein and RNA molecules. The theory can successfully unify innovations that occur at different levels of organization. It captures known features of biological innovation, including the fact that many innovations occur multiple times independently, and that they combine existing parts of a system to new purposes. It also argues that environmental change is important to create biological systems that are both complex and robust, and shows how such robustness can facilitate innovation. Beyond that, the theory can reconcile neutralism and selectionism, as well as explain the role of phenotypic plasticity, gene duplication, recombination, and cryptic variation in innovation. Finally, its principles can be applied to technological innovation, and thus open to human engineering endeavours the powerful principles that have allowed life's spectacular success.

The Biopolitics of Embryos and Alphabets - A Reproductive History of the Nonhuman (Hardcover): Ruth A. Miller The Biopolitics of Embryos and Alphabets - A Reproductive History of the Nonhuman (Hardcover)
Ruth A. Miller
R3,272 Discovery Miles 32 720 Ships in 10 - 15 working days

In recent decades there has been an explosion in work in the social and physical sciences describing the similarities between human and nonhuman as well as human and non-animal thinking. This work has explicitly decentered the brain as the sole, self-contained space of thought, and it has found thinking to be an activity that operates not only across bodies but also across bodily or cellular membranes, as well as multifaceted organic and inorganic environments. For example, researchers have looked at the replication and spread of slime molds (playfully asking what would happen if they colonized the earth) to suggest that they exhibit 'smart behavior' in the way they move as a potential way of considering the spread of disease across the globe. Other scholars have applied this model of non-human thought to the reach of data mining and global surveillance. In The Biopolitics of Alphabets and Embryos, Ruth Miller argues that these types of phenomena are also useful models for thinking about the growth, reproduction, and spread of political thought and democratic processes. Giving slime, data and unbounded entities their political dues, Miller stresses their thinking power and political significance and thus challenges the anthropocentrism of mainstream democratic theories. Miller emphasizes the non-human as highly organized, systemic and productive of democratic growth and replication. She examines developments such as global surveillance, embryonic stem cell research, and cloning, which have been characterized as threats to the privacy, dignity, and integrity of the rational, maximizing and freedom-loving democratic citizen. By shifting her level of analysis from the politics of self-determining subjects to the realm of material environments and information systems, Miller asks what might happen if these alternative, nonhuman thought processes become the normative thought processes of democratic engagement.

Statistical Genomics - Linkage, Mapping, and QTL Analysis (Hardcover): Ben Hui Liu Statistical Genomics - Linkage, Mapping, and QTL Analysis (Hardcover)
Ben Hui Liu
R5,402 Discovery Miles 54 020 Ships in 10 - 15 working days

Genomics, the mapping of the entire genetic complement of an organism, is the new frontier in biology. This handbook on the statistical issues of genomics covers current methods and the tried-and-true classical approaches.

Green Technologies for the Environment (Hardcover): Sherine Obare, Rafael Luque Green Technologies for the Environment (Hardcover)
Sherine Obare, Rafael Luque
R5,471 Discovery Miles 54 710 Ships in 10 - 15 working days

The book "Green Technologies for the Environment" brings together experts in the field of biotechnology, chemistry, chemical engineering, environmental engineering and toxicology from both academia and industry, to discuss green processes for the environment. The topics included finding replacements for crude oil to meet both our energy needs as well as the supply of chemicals for the production of essential products, advances in chemical processing, waste valorization, alternative solvents, and developments in homogeneous and heterogeneous catalysis as well as enzyme-based processes for chemical transformations. Advances in green chemistry concepts will further enhance the field through the design of new chemicals and solvents. In addition, obtaining a better understanding of the mechanistic pathways involved in various reactions is essential toward advances in the field. The goal of the work described in each of the chapters is to address the need for best practices for chemical processes and for the production of chemicals, while promoting sustainability.

Importance of Chirality to Flavor Compounds (Hardcover): Gary Takeoka, Karl-Heinz Engel Importance of Chirality to Flavor Compounds (Hardcover)
Gary Takeoka, Karl-Heinz Engel
R5,465 Discovery Miles 54 650 Ships in 10 - 15 working days

Chiral molecules are ubiquitous in nature. Thus, it is not surprising to come across this phenomenon in the world of flavor substances. This book provides an overview on the analytical procedures currently applied to analyze chiral flavor substances at trace levels. It demonstrates several examples for the application of these techniques to determine naturally occurring enantiomeric compositions of chiral key flavor compounds in various natural systems. In addition to the analytical aspects, the contributions focus on the sensory properties of enantiomers and enlarge our knowledge on the correlation between configurations and odor properties and intensities of chiral flavor compounds. The practical importance of the topic is reflected by a discussion of merits and limitations of chiral analysis for the authenticity control of food flavorings. In addition, examples for the use of enzymes and microorganisms to obtain enantiopure flavor substances and thus to meet legal requirements for "natural" labeling are presented. Finally, the book covers aspects recently getting more and more in the focus of flavor science: What are the physiological mechanisms underlying the perception of sensory properties and does chirality matter in that respect?

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