Filling an obvious gap in the scientific literature, this practice-oriented reference is the first to tie together the working knowledge of large
screening centers in the pharmaceutical and biotechnological field. It spans the entire fi eld of this emerging discipline, from compound
acquisition to collection optimization for specific purposes, to technology and quality control. In so doing, it applies two decades of expertise gathered by several large pharmaceutical companies to current and future challenges in high-throughput screening. With its treatment of libraries of small molecules as well as biobanks containing biomolecules, microorganisms and tissue samples, this reference is universally applicable for any molecular scientist involved in a large screening program.

Bacterial cellulose (BC) is a natural polymer produced by different microbial cells. Its unique structural, physico-chemical, mechanical, thermal, and biological properties offer much potential for use in diverse applications in the biomedical, electronics, energy, and environmental fields, among others. This text provides an overview of the synthesis, characterization, modification, and application of BC. * Discusses sources, characterization, and biosynthesis of BC * Covers composites and aerogels based on BCs * Describes development of BCs from waste and challenges in large-scale production of BCs * Explores a variety of applications such as environmental, industrial, and biomedical This book will be of great interest to researchers and industry professionals in materials science, chemical engineering, chemistry, and other related fields seeking to learn about the synthesis and application of this important material.

Tissue Engineering Strategies for Organ Regeneration addresses the existing and future trends of tissue engineering approaches for organ/tissue regeneration or repair. This book provides a comprehensive summary of the recent improvement of biomaterials used in scaffold-based tissue engineering, and the tools and different protocols needed to design tissues and organs. The chapters in this book provide the in-depth principles for many of the supporting and enabling technologies including the applications of BioMEMS devices in tissue engineering, and the combination of organoid formation and three dimensional (3D) bioprinting. The book also highlights the advances and strategies for regeneration of three-dimensional microtissues in microcapsules, tissue reconstruction techniques, and injectable composite scaffolds for bone tissue repair and augmentation. Key Features: Addresses the current obstacles to tissue engineering applications Provides the latest improvements in the field of integrated biomaterials and fabrication techniques for scaffold-based tissue engineering Shows the influence of microenvironment towards cell-biomaterials interactions Highlights significant and recent improvements of tissue engineering applications for the artificial organ and tissue generation Describes the applications of microelectronic devices in tissue engineering Describes different current bioprinting technologies

This book examines the bioeconomy concept, analysing the opportunities it can generate, the constraints and the potential benefits for society. The main objective of bioeconomy is to promote economic development, by creating jobs and enhancing the sustainable utilization of bio-resources. A primary driver of bioeconomy strategy, therefore, is the need to respond to the growing population's food and economic requirements. While today research and literature related to bioeconomy are limited, this book presents a unique collection of perspectives on the complex dimensions of the bioeconomy debate. Drawing on the experiences from Europe, Asia and Africa, it presents an international overview. The chapters address a wide range of issues, including coastal-land interactions, ecosystem services, food production, rural development, agriculture, forest management and bioenergy. As a whole, the volume outlines what role bioeconomy can play in contributing to the United Nations Sustainable Development Goals (SDGs) without compromising on the ecological sustainability and equitable distribution of benefits. The book concludes by providing recommendations for developing bioeconomy in respective sectors (agriculture, forestry, fisheries, renewable energy) and directions for planning future bioeconomy programmes and strategies. The Bioeconomy Approach will be of great interest to students and scholars of ecological economics, development economics and environmental economics, as well as policy-makers and practitioners involved in sustainable development.

In her quest for global leadership in science and technology, the People's Republic of China has attained top ranks in the number of scientific publications, "hot papers," or national and international patent applications. However, analysis of the underlying structures and mechanisms is hindered by the sheer flood of data, stringent government control of all media, and ambiguities inherent in translation from Chinese. This book overcomes these difficulties and provides a concise picture of biotechnology-related research and development in China. It begins with brief accounts of China's geography, people, political and administrational structure, economy, finance, infrastructure related to science and technology, and educational system. It presents succinct accounts on structures and developments in biomedicine, diagnostics, agriculture, fermented food, bioindustry, and environmental biotechnology, with reference to government, industry, and academia. Finally, it predicts the next steps in Chinese biotechnology for the national agenda and, in view of China's ambitious global development strategy, the Belt and Road Initiative.

Connecting theory with real-life applications, this is the first ever textbook to equip students with a comprehensive knowledge of all the key concepts in bionanotechnology. By bridging the interdisciplinary gap from which bionanotechnology emerged, it provides a systematic introduction to the subject, accessible to students from a wide variety of backgrounds. Topics range from nanomaterial preparation, properties and biofunctionalisation, and analytical methods used in bionanotechnology, to bioinspired and DNA nanotechnology, and applications in biosensing, medicine and tissue engineering. Throughout the book, features such as 'Back to basics' and 'Research report' boxes enable students to build a strong theoretical knowledge and to link this to practical applications and up-to-date research. With over 200 detailed, full-colour illustrations and more than 100 end-of-chapter problems, this is an essential guide to bionanotechnology for any student studying this exciting, fast-developing and interdisciplinary field.

Explores the cutting edge technologies including nanotechnology based bioremediation, value added products from waste and emerging techniques related to environmental risk assessment and monitoring Reviews the current methods being applied in the field of environment for pollution control, waste management, biodegradation of organic and inorganic pollutants etc. Provides in-depth knowledge to the latest advancements in the field of environmental biotechnology like bioleaching, biomining, advances in biotechnology based conservation of biodiversity Introduces the undergraduate and post graduate students towards basic concepts of environmental biotechnology and allied fields Discusses different products like biofuels, biopolymers, biosensors being produced using biotechnological methods thus contributing towards goal of sustainable development

Biotribology includes tribological phenomena of natural and implant surface interactions under relative motion in the human body. Biotribology: Emerging Technologies and Applications disseminates ideas and research trends in biotribology and presents pioneering recent research advances impacting the field, focusing on the roles of mathematics, chemistry, physics, materials, and mechanical engineering. Discusses lubrication of joint replacements, computational modeling of biotribology and multibody biomechanical models Describes metal-organic frameworks, medical friction pairs, and electrochemical techniques to tribocorrosion tests Covers state of the art and future technological developments and applications, as well as challenges and opportunities Biotribology is an important and growing field, and the topics covered in this book will be of great interest to the international tribology community, appealing to readers working in the fields of materials science, biomedical engineering, biotechnology, mechanical engineering, and related areas.

Sustainable Bioprocessing for a Clean and Green Environment: Concepts and Applications highlights the importance of waste to health in which waste is safely converted to value-added products via bioprocess technologies. Providing fundamental concepts and applications, this book also offers readers the methodology behind the operation of a variety of biological processes used in developing valuable products from waste. Features: Discusses synthesis and use of environmentally friendly biobased materials, such as biopolymer films and biobased plasticizers Highlights nanotechnology applications in the treatment of pollution and emphasizes the synthesis of biogenic nanomaterials for environmental remediation Describes the use of biosurfactants and emerging algal technologies, such as applications of microalgae in nutraceuticals and biofuel production Details delignification for lignocellulosic biomass This interdisciplinary book offers researchers and practitioners in chemical engineering, environmental engineering, and related fields a broad perspective on fundamentals, technologies, and environmental applications of sustainable bioprocessing.

Sugarcane is the most important plant source for sugar and alcohol production and is cultivated in more than 80 countries in tropical and subtropical areas. However, environmental factors negatively influence its yield and jeopardize the prospect to meet the increasing demand for sugar, other sugarcane derived by products and bioethanol. The development of stress tolerant plants is fundamental for the maintenance and increase of crop yields. Biotechnology to Enhance Sugarcane Productivity and Stress Tolerance provides a comprehensive account of both theoretical and practical aspects of sugarcane production. It contains extensive coverage of genome mapping and molecular breeding in sugarcane and presents the status of the elucidation and improvement of plant genomes of economic interest. Through 14 chapters written by eminent scientists with global influence, this book examines various methods for sugarcane improvement through biotechnology. The book focuses on genetic and physical mapping, positioning, cloning, and monitoring of desirable genes using biotechnological approaches for high sugarcane productivity and the development of stress tolerance. Additional information includes the bioengineering of sugarcane, procedures to boost productivity, genetics and assessments for resistance to drought and salinity, genetics for high yields, and various topics of research on sugarcane genetics. It serves as a detailed reference source for cane growers, sugar and sugarcane technologists, students, and professors.

Recent advances in nanotechnology has led the nanomaterials into the realm of sensing applications. This descriptive book utilizes a multi-disciplinary approach to provide extensive information about sensors and elucidates the impact of nanotechnology on development of chemical and biosensors for diversified applications. The main focus of this book is not only the inclusion of various research works, which have already been reported in literature, but also to make a potential conclusion about the mechanism behind this. This book will serve as an invaluable tool for both frontline researchers and academicians to work towards the future development of nanotechnology in sensing devices.

This book highlights progress in terms of Virus Biology and Infection Detection, Prevention, and Control, along with Screening, Testing, and Detection Techniques, that will provide learners and researchers (from basic to advanced) with the most innovative computer-driven methodologies for the fight against COVID-19. In addition, this book also covers the Pre- and Post-Impact of the COVID-19 Pandemic Crisis that will definitely provide useful content for researchers to think broadly about the analytical areas affected by COVID-19. This ultimately shows different paths to the same destination to help understand the nature of the COVID-19 pandemic and how to avoid it in the future.

Value-Added Biocomposites: Technology, Innovation, and Opportunity explores advances in research, processing, manufacturing, and novel applications of biocomposites. It describes the current market situation, commercial competition, and societal and economic impacts and advantages of substituting biocomposites for conventional composites, including natural fibers and bioplastics. FEATURES Discusses manufacturing and processing procedures that focus on improving physical, mechanical, thermal, electrical, chemical, and biological properties and achieving required specifications of downstream industries and customers Analyzes the wide range of available base materials and fillers of biocomposites and bioplastics in terms of the strength and weaknesses of materials and economic potential in the market Displays special and unique properties of biocomposites in different market sectors Showcases the insight of expert scientists and engineers with first-hand experience working with biocomposites across various industries Covers environmental factors, life cycle assessment, and waste recovery Combining technical, economic, and environmental topics, this work provides researchers, advanced students, and industry professionals a holistic overview of the value that biocomposites add across a variety of engineering applications and how to balance research and development with practical results.

Nanomaterials in Bionanotechnology: Fundamentals and Applications offers a comprehensive treatment of nanomaterials in biotechnology from fundamentals to applications, along with their prospects. This book explains the basics of nanomaterial properties, synthesis, biological synthesis, and chemistry and demonstrates how to use nanomaterials to overcome problems in agricultural, environmental, and biomedical applications. Features Covers nanomaterials for environmental analysis and monitoring for heavy metals, chemical toxins, and water pollutant detection Describes nanomaterials-based biosensors and instrumentation and use in disease diagnosis and therapeutics Discusses nanomaterials for food processing and packaging and agricultural waste management Identifies challenges in nanomaterials-based technology and how to solve them This work serves as a reference for industry professionals, advanced students, and researchers working in the discipline of bionanotechnology.

This book encompasses the most updated and recent account of research and implementation of Microbial Electrochemical Technologies (METs) from pioneers and experienced researchers in the field who have been working on the interface between electrochemistry and microbiology/biotechnology for many years. It provides a holistic view of the METs, detailing the functional mechanisms, operational configurations, influencing factors governing the reaction process and integration strategies. The book not only provides historical perspectives of the technology and its evolution over the years but also the most recent examples of up-scaling and near future commercialization, making it a must-read for researchers, students, industry practitioners and science enthusiasts. Key Features: Introduces novel technologies that can impact the future infrastructure at the water-energy nexus. Outlines methodologies development and application of microbial electrochemical technologies and details out the illustrations of microbial and electrochemical concepts. Reviews applications across a wide variety of scales, from power generation in the laboratory to approaches. Discusses techniques such as molecular biology and mathematical modeling; the future development of this promising technology; and the role of the system components for the implementation of bioelectrochemical technologies for practical utility. Explores key challenges for implementing these systems and compares them to similar renewable energy technologies, including their efficiency, scalability, system lifetimes, and reliability.

Since the potential toxicity of silver nanoparticles (Ag NPs) has raised serious concerns in the biomaterials and biomedical engineering community, Silver Nanoparticles for Antibacterial Devices: Biocompatibility and Toxicity brings together the synthesis, the physicochemical properties and the biological actions of Ag NPs, as well as the clinical demands for fabricating antibacterial medical devices, discussing how to suppress the side effects of nanomaterials and how to impart to them the selective toxicity. This book presents the two primary paradigms that have emerged in probing the antibacterial applications of Ag NPs, i.e. the active attacking releasing way and the conservative defending approach by taking advantage of various short-range actions; it shows readers how the ways in which Ag NPs have behaved can be engineered purposively. With contributions from leading international experts and extensive references listed in each chapter, this volume provides the general principles on controlling the physicochemical behaviors of nanomaterials and managing their toxicity risks.

Describes extensively the design and microfabrication of nanosensors based on nanotechnological tools. Provides a wide range of bioplatforms based on e.g., carbon nanostructures and Describes extensively a large number of application as a part of Nanomaterial based biosensors.

Subcritical water is a green extraction solvent compared to conventional extraction solvents. While experimental results on subcritical water extraction (SWE) technology have been published piecemeal, there has been no comprehensive review of the state of the art. Green Extraction in Separation Technology fills that gap, serving to cover extracting with subcritical water as an environmentally friendly solvent. FEATURES Presents new technologies for extracting natural compounds from plants and compares the advantages and disadvantages versus SWE Explains research on SWE over the last 15 years Offers an overview of the solubility of different compounds in SWE and related theoretical content Discusses modeling of SWE and describes the development of a new model for this process This monograph is aimed at researchers and advanced students in chemical and biochemical engineering.

This book brings together contributions from leading scientists, academics, and experts from the oil and gas industry to discuss microbial-related problems faced by the industry and how bioinformatics and an interdisciplinary scientific approach can address these challenges. Microbial Bioinformatics in the Oil and Gas Industry: Applications to Reservoirs and Processes presents the major industrial problems caused by microbes (e.g., souring, biocorrosion) as well as the beneficial activities (e.g., biofuels, bioremediation). FEATURES Offers a detailed description of how bioinformatics has advanced our understanding of numerous issues in the oil and gas industry Covers cases from geographically diverse oil fields, laboratories, and research groups Contains fundamentals and applied information of relevance to the oil and gas sector Presents contributions from a team of international experts across industry and academia With its cross-disciplinary approach, this comprehensive book provides microbial ecologists, molecular biologists, operators, engineers, chemists, and academics involved in the sector with an improved understanding of the significance of microbial bioinformatics applications in the oil and gas industry.

Microbial species isolated from extreme and pristine habitats are always diverse, which indicates biomolecules secreted by these species might have importance. A cure for disease is a desire considering the catastrophic situations that threaten the lives of humans and animals. Currently, the world is facing the health, social and economic, and diplomatic impacts of infectious communicable diseases caused by bacteria and viruses. It is a necessity to understand the huge microbial diversity residing everywhere with us in this world. Microorganisms are species that were born at the start of “life” and will stay after the end of all other forms of life in this world. This unseen majority has significant effects on the biogeochemical cycle as well as has numerous medical and non-medical applications. So, the ability of microorganisms to produce bioactive compounds and how they can be used in different fields, especially medicine and health care, have been discussed in this book.

Anthropogenic activity has clearly altered the N cycle contributing (among other factors) to climate change. This book aims to provide new biotechnological approach representing innovative strategies to solve specific problems related to the imbalance originating in the N cycle. Aspects such as new conceptions in agriculture, wastewater treatment, and greenhouse gas emissions are discussed in this book with a multidisciplinary vision. A team of international authors with wide experience have contributed up-to-date reviews, highlighting scientific principles and their environmental importance and integrating different biotechnological processes in environmental technology.

Pandemics are often associated with viruses and bacteria occurring in wildlife in natural environments. Thus, diseases of epidemic and pandemic scale are mostly zoonotic, some of which include AIDS, Zika Virus, Severe Acute Respiratory Syndrome (SARS), and COVID-19. The book seeks to explore the documented history of pandemics and various epidemics which have the potential of turning into pandemics with the warming climate, pollution, and environmental destruction. The book covers some of the most essential elements of the diseases of pandemic nature and their relationship with the environment. Environment as a reservoir of human diseases Climate Change: Emerging Driver of Infectious Diseases Occurrence and Environmental Dimensions of Specific Pandemics and Epidemics Pandemics, Environment, and Globalization: Understanding the Interlinkage in the Context of COVID-19 Climate Change and Zoonotic Diseases: Malaria, Plague, Dengue, Encephalitis Tuberculosis: An old enemy of mankind and way to next pandemic Lassa fever in Nigeria: case fatality ratio, social consequences, and prevention There are cases where scientists fear that there are many epidemics which have the potential of turning into pandemics, if not paid attention to, and measures not being taken to control these occurrences. This book attempts to provide integrated risk assessment on COVID -19 like pandemics. It covers fundamental factors of global disease outbreaks through the complexity and severity of consequences. Information collated in this book would help in the design of mitigation measures, including behavioral changes that would prevent the emergence of such pandemics, thus protecting human life and minimize losses incurred due to diseases of such magnitude.

The book Extreme Environments: Unique Ecosystems - Amazing Microbes is an attempt to showcase the uniqueness of extremophiles, the largely unexplored group that has the abilities to function in hostile conditions and represent the very ancient life forms that thrived on earth billions of years ago. The book covers a wide range of research achievements in the field of microbiology of extreme environments right from the conventional approaches of cultivation to recently evolved high throughput sequencing technologies. The book provides a broad spectrum of information about the taxonomy, physiology, ecology and biotechnological applications of extremophiles from various extreme environments across the globe.

Freeze Drying of Pharmaceutical Products provides an overview of the most recent and cutting-edge developments and technologies in the field, focusing on formulation developments and process monitoring and considering new technologies for process development. This book contains case studies from freeze dryer manufacturers and pharmaceutical companies for readers in industry and academia. It was contributed to by lyophilization experts to create a detailed analysis of the subject matter, organically presenting recent advancements in freeze-drying research and technology. It discusses formulation design, process optimization and control, new PAT-monitoring tools, multivariate image analysis, process scale-down and development using small-scale freeze-dryers, use of CFD for equipment design, and development of continuous processes. This book is for industry professionals, including chemical engineers and pharmaceutical scientists.