Almost all synthetic materials over time induce some level of inflammation and fibrosis. Therefore, even though the successes of biomaterials science in producing acceptable solutions to the problem of biocompatibility have been remarkable, there remains enormous opportunity for improvement. The goal is the development of intelligent materials that replicate and mimic the ability of tissues and biological materials to adapt and renew. This book describes the synthesis and the analysis of new smart polymeric materials and their practical implications in nanomedicine and biotechnology. It offers a comprehensive overview, gathering recent and innovative research on multiple aspects within the field of smart polymeric materials that offer new perspectives in developing current advanced biotechnologies. The text contains both experimental and theoretical issues that reflect the impact of the materials characteristics in target applications. It deals with recent advances in the design of new polymeric materials for advanced applications but also on the study of their structure-properties relationship in order to move from completely inert, static structures to flexible ones capable to respond to environmental changes.

The availability of molecular imaging and measurement systems enables today's biologists to swiftly monitor thousands of genes involved in a host of diseases, a critical factor in specialized drug development. Systems Biology and Bioinformatics: A Computational Approach provides students with a comprehensive collection of the computational methods used in what is being coined the digital era of biology. Written by field experts with proven track records, this authoritative textbook first provides an introduction to systems biology and its impact on biology and medicine. The book then reviews the basic principles of molecular and cell biology using a system-oriented approach, with a brief description of the high-throughput biological experiments that produce databases. The text includes techniques to discover genes, perform nucleotide and amino acid sequence matching, and estimate static gene dynamic pathways. The book also explains how to use system-oriented models to predict the behavior of biological systems for important applications such as rational drug design. The numerous examples and problem sets allow students to confidently explore practical systems biology applications using real examples with real biological data, making Systems Biology and Bioinformatics: A Computational Approach an ideal text for senior undergraduate and first-year graduate students.

Microfluidics-based biochips combine electronics with biochemistry, providing access to new application areas in a wide variety of fields. Continued technological innovations are essential to assuring the future role of these chips in functional diversification in biotech, pharmaceuticals, and other industries. Revolutionary guidance on design, optimization, and testing of low-cost, disposable biochips Microfluidic Biochips: Design Automation and Optimization comprehensively covers the appropriate design tools and in-system automation methods that will help users adapt to new technology and progress in chip design and manufacturing. Based on results from several Duke University research projects on design automation for biochips, this book uses real-life bioassays as examples to lay out an automated design flow for creating microfluidic biochips. It also develops solutions to the unique problems associated with that process. Highlights the design of the protein crystallization chip to illustrate the benefits of automated design flowIn addition to covering automated design, the authors provide a detailed methodology for the testing, use, and optimization of robust, cost-efficient, manufacturable digital microfluidic systems used in protein crystallization and other areas. The invaluable tools and practices presented here will help readers to: Address optimization problems related to layout, synthesis, droplet routing, and testing for digital microfluidic biochips Make routing-aware, architectural-level design choices and defect-tolerant physical design decisions simultaneously Achieve the optimization goal, which includes minimizing time-to-response, chip area, and test complexity Effectively deal with practical issues such as defects, fabrication cost, physical constraints, and application-driven design The authors present specialized pin-constrained design techniques for making biochips with a focus on cost and disposability. They also discuss chip testing to ensure dependability, which is key to optimizing safety-critical applications such as point-of-care medical diagnostics, on-chip DNA analysis, automated drug discovery, air-quality monitoring, and food-safety testing. This book is an optimal reference for academic and industrial researchers in the areas of digital microfluidic biochips and electronic design automation.

With the advent of new technologies and acquired knowledge, the number of fields in omics and their applications in diverse areas are rapidly increasing in the postgenomics era. Such emerging fields-including pharmacogenomics, toxicogenomics, regulomics, spliceomics, metagenomics, and environomics-present budding solutions to combat global challenges in biomedicine, agriculture, and the environment. OMICS: Applications in Biomedical, Agricultural, and Environmental Sciences provides valuable insights into the applications of modern omics technologies to real-world problems in the life sciences. Filling a gap in the literature, it offers a broad, multidisciplinary view of current and emerging applications of omics in a single volume. Written by highly experienced active researchers, each chapter describes a particular area of omics and the associated technologies and applications. Topics covered include: Proteomics, epigenomics, and pharmacogenomics Toxicogenomics and the assessment of environmental pollutants Applications of plant metabolomics Nutrigenomics and its therapeutic applications Microalgal omics and omics approaches in biofuel production Next-generation sequencing and omics technology for transgenic plant analysis Omics approaches in crop improvement Engineering dark-operative chlorophyll synthesis Computational regulomics Omics techniques for the analysis of RNA splicing New fields, including metagenomics, glycomics, and miRNA Breast cancer biomarkers for early detection Environomics strategies for environmental sustainability This timely book explores a wide range of omics application areas in the biomedical, agricultural, and environmental sciences. Throughout, it highlights working solutions as well as open problems and future challenges. Demonstrating the diversity of omics, it introduces readers to state-of-the-art developments and trends in omics-driven research.

A ubiquitous tool in mathematical biology and chemical engineering, the chemostat often produces instabilities that pose safety hazards and adversely affect the optimization of bioreactive systems. Singularity theory and bifurcation diagrams together offer a useful framework for addressing these issues. Based on the authors' extensive work in this field, Dynamics of the Chemostat: A Bifurcation Theory Approach explores the use of bifurcation theory to analyze the static and dynamic behavior of the chemostat. IntroductionThe authors first survey the major work that has been carried out on the stability of continuous bioreactors. They next present the modeling approaches used for bioreactive systems, the different kinetic expressions for growth rates, and tools, such as multiplicity, bifurcation, and singularity theory, for analyzing nonlinear systems. ApplicationThe text moves on to the static and dynamic behavior of the basic unstructured model of the chemostat for constant and variable yield coefficients as well as in the presence of wall attachment. It then covers the dynamics of interacting species, including pure and simple microbial competition, biodegradation of mixed substrates, dynamics of plasmid-bearing and plasmid-free recombinant cultures, and dynamics of predator-prey interactions. The authors also examine dynamics of the chemostat with product formation for various growth models, provide examples of bifurcation theory for studying the operability and dynamics of continuous bioreactor models, and apply elementary concepts of bifurcation theory to analyze the dynamics of a periodically forced bioreactor. Using singularity theory and bifurcation techniques, this book presents a cohesive mathematical framework for analyzing and modeling the macro- and microscopic interactions occurring in chemostats. The text includes models that describe the intracellular and operating elements of the bioreactive system. It also explains the mathematical theory behind the models.

This book covers recent research on the COVID-19 pandemic. It includes the analysis, implementation, usage, and proposed ideas and models with architecture to handle the COVID-19 outbreak. Using advanced technologies such as artificial intelligence (AI) and machine learning (ML), techniques for data analysis, this book will be helpful to mitigate exposure and ensure public health. We know prevention is better than cure, so by using several ML techniques, researchers can try to predict the disease in its early stage and develop more effective medications and treatments. Computational technologies in areas like AI, ML, Internet of Things (IoT), and drone technologies underlie a range of applications that can be developed and utilized for this purpose. Because in most cases there is no one solution to stop the spreading of pandemic diseases, and the integration of several tools and tactics are needed. Many successful applications of AI, ML, IoT, and drone technologies already exist, including systems that analyze past data to predict and conclude some useful information for controlling the spread of COVID-19 infections using minimum resources. The AI and ML approach can be helpful to design different models to give a predictive solution for mitigating infection and preventing larger outbreaks. This book: Examines the use of artificial intelligence (AI), machine learning (ML), Internet of Things (IoT), and drone technologies as a helpful predictive solution for controlling infection of COVID-19 Covers recent research related to the COVID-19 pandemic and includes the analysis, implementation, usage, and proposed ideas and models with architecture to handle a pandemic outbreak Examines the performance, implementation, architecture, and techniques of different analytical and statistical models related to COVID-19 Includes different case studies on COVID-19 Dr. Chhabi Rani Panigrahi is Assistant Professor in the Department of Computer Science at Rama Devi Women's University, Bhubaneswar, India. Dr. Bibudhendu Pati is Associate Professor and Head of the Department of Computer Science at Rama Devi Women's University, Bhubaneswar, India. Dr. Mamata Rath is Assistant Professor in the School of Management (Information Technology) at Birla Global University, Bhubaneswar, India. Prof. Rajkumar Buyya is a Redmond Barry Distinguished Professor and Director of the Cloud Computing and Distributed Systems (CLOUDS) Laboratory at the University of Melbourne, Australia.

Many varieties of new, complex diseases are constantly being discovered, which leaves scientists with little choice but to embrace innovative methods for controlling the invasion of life-threatening problems. The use of nanotechnology has given scientists an opportunity to create nanomaterials that could help medical professionals in diagnosing and treating problems quickly and effectively. Bioengineered Nanomaterials presents in-depth information on bioengineered nanomaterials currently being developed in leading research laboratories around the world. In particular, the book focuses on nanomaterials for biomedical applications. This collection brings together novel methodologies and strategies adopted in the research and development of bioengineered nanomaterials and technology. Renowned international researchers discuss topics including: Nanoemulsions as a vaccine adjuvant Bioceramic nanomaterials in medical applications Natural and synthetic nanoporous membranes for cell encapsulation therapy Inorganic nanoparticle materials for the controlled release of drugs Nanomedicine in brain tumor treatment Nanoparticles for the treatment of solid tumors and metastasis Near-infrared-resonant gold nanoshells and carbon nanotubes in tumor imaging Toxicity testing and bioapplications of silver nanoparticles Innovative approaches to improve bioactive properties and molecular signaling in cells to stimulate bone repair The book is written for readers from diverse backgrounds across chemistry, physics, materials science and engineering, medical science, pharmacy, biotechnology, and biomedical engineering. It offers a comprehensive view of cutting-edge research on nanomaterials of biotechnological importance.

The development of modern biotechnology has varied considerably from country to country. Typically, there are wide technology gaps between developing and industrialised countries and considerable differences in investment and regulatory systems, often creating a need for policy intervention. This innovative book examines the development and evolution of biotechnology in industrialised and developing countries. The author first explores efforts made by policymakers and the leaders in the field to reduce technology gaps, and analyses the development of financial mechanisms and regulatory frameworks to hasten the adoption and diffusion of biotechnology. The second section looks at the relationship between biotechnology and its resource base, biological diversity. The author emphasizes the interdependency between biodiversity and biological R&D in an attempt to simplify the debate on the conservation of biological diversity. The last section focuses on the potential positive and negative impacts of biotechnology and its contribution towards sustaining biodiversity. The Emergence and Growth of Biotechnology will be of great interest to undergraduate and postgraduate economics students interested in the economics of technology, economic development and biotechnology and environmental conservation.

This third volume of the handbook presents a representative sample of the population papers in the field of petrodiesel fuels. Following the substantial public concerns on the adverse impact of the emissions from petrodiesel fuels on the environment and human health, the research has intensified in the areas related to the reduction of these adverse effects. Thus, bioremediation of spills from crude oils and petrodiesel fuels at sea and soils as well as desulfurization of petrodiesel fuels have emerged as publicly important research areas. Similarly, the emissions from diesel fuel exhausts, due to their adverse effects on both human health and environment, have been researched more in recent years. These emissions cover particulate emissions, aerosol emissions, and NOx emissions. Research on the adverse impact of petrodiesel fuel exhaust emissions on human health has primarily progressed along the lines of respiratory illnesses, cancer, and other illnesses, such as cardiovascular illnesses, brain illnesses, and reproductive system illnesses, through human, animal, and in vitro studies. It is clear that these illnesses caused by the petrodiesel fuel exhaust emissions have been one of the most significant reasons to develop alternative biodiesel fuels. Part IX presents a representative sample of the population papers in the field of crude oils covering major research fronts. It covers crude oil spills in general, crude oil spills and their cleanup, properties and removal of crude oils, biodegradation of crude oil-contaminated soils, and crude oil recovery besides an overview paper. Part X presents a representative sample of the population papers in the field of petrodiesel fuels in general covering major research fronts. It covers combustion of biodiesel fuels in diesel engines, bioremediation of biodiesel fuel-contaminated soils, biodiesel power generation, and desulfurization of diesel fuels besides an overview paper. Part XI presents a representative sample of the population papers in the field of emissions from petrodiesel fuels covering major research fronts. It covers diesel emission mitigation, diesel particulate emissions, and diesel NOx emissions, besides an overview paper. Part XII presents a representative sample of the population papers in the field of the health impact of the emissions from petrodiesel fuels covering major research fronts. It covers respiratory illnesses, cancer, cardiovascular, brain, and reproductive system illnesses, besides an overview paper. This book will be useful to academics and professionals in the fields of Energy Fuels, Public Environmental Occupational Health, Pharmacology, Pharmacy, Immunology, Respiratory System, Allergy, and Oncology. Ozcan Konur is both a materials scientist and social scientist by training. He has published around 200 journal papers, book chapters, and conference papers. He has focused on the bioenergy and biofuels in recent years. In 2018, he edited Bioenergy and Biofuels, which brought together the work of over 30 experts in their respective field. He also edited the Handbook of Algal Science, Technology, and Medicine with a strong section on the algal biofuels in 2020.

Microbes bear a great potential for their biotechnological applications. Without microbes biotechnology would be a limited science. In recent years, the scope of application and significance of microbiology has enlarged manifold. They are being employed since several decades for large-scale production of a variety of biochemicals ranging from alcohols to organic chemicals, antibiotics, enzymes and in processing of foods and feeds, etc. The book MICROBIAL BIOTECHNOLOGY: Methods and Applications covers an amazing range of topics from microbiology and their biotechnological applications in the field of industry, agriculture, food, pharmaceutics, medicine, environment etc. contributed by eminent subject experts, academicians, researchers and scientists from India and Abroad. This book would cater to the need of the graduate and post graduate students pursuing their study in any branch of life-sciences, researchers and scientists working in the laboratories and industries involved in the study and research in the field of microbes and their biotechnological applications. Preface / Production of Pyruvic Acid, 2-keto Acids and Chiral 2-hydroxy Acids using Glycolate Oxidase and Catalase Co-expressed in Pichia pastoris / Application of Immobilized Microbial Cells for Enzyme Production with Special Reference to Tannase / Utilization of Algal Biomass as Biofuels / Microbial Degradation of Caffeine, Methylxanthines and Its Biotechnological Applications / Bacillus thuringiensis: Biodiversity to Biotechnology / Agrobacterium tumefaciens: A Powerful Tool for Transkingdom Transfer of Genetic Materials / An Overview on Microbial Biocontrol for a Sustainable Horticultural Practice / Mushroom Glucan as Biological Response Modifier in Therapy / In silico Identification of Potential Therapeutic Targets in Pathogens An Overview / Microbial Studies to Establish Possible Biocompatible Coatings of Ferrofluids, Synthesized Biomimetically, for Biomedical Applica

Brings together recent innovations and practices of bio-based technologies for environmental Remediation Outlines major Bio-Based Technologies Contains both practical and theoretical latest and broad aspects of environment management through bio-based innovative technology.

The six years that have passed since the publication of the first edition have brought significant advances in both biofilm research and biofilm engineering, which have matured to the extent that biofilm-based technologies are now being designed and implemented. As a result, many chapters have been updated and expanded with the addition of sections reflecting changes in the status quo in biofilm research and engineering. Emphasizing process analysis, engineering systems, biofilm applications, and mathematical modeling, Fundamentals of Biofilm Research, Second Edition provides the tools to unify and advance biofilm research as a whole. Retaining the goals of the first edition, this second edition serves as: A compendium of knowledge about biofilms and biofilm processes A set of instructions for designing and conducting biofilm experiments A set of instructions for making and using various tools useful in biofilm research A set of computational procedures useful in interpreting results of biofilm research A set of instructions for using the model of stratified biofilms for data interpretation, analysis, and biofilm activity prediction

Intellectual property rights (IPRs), particularly patents, occupy a prominent position in innovation systems, but to what extent they support or hinder innovation is widely disputed. Through the lens of biotechnology, this book delves deeply into the main issues at the crossroads of innovation and IPRs to evaluate claims of the positive and negative impacts of IPRs on innovation. An international group of scholars from a range of disciplines - economic geography, health law, business, philosophy, history, public health, management - examine how IPRs actually operate in innovation systems, not just from the perspective of theory but grounded in their global, regional, national, current and historical contexts. In so doing, the contributors seek to uncover and move beyond deeply held assumptions about the role of IPRs in innovation systems. Scholars and students interested in innovation, science and technology policy, intellectual property rights and technology transfer will find this volume of great interest. The findings will also be of value to decision makers in science and technology policy and managers of intellectual property in biotechnology and venture capital firms.

To succeed in the lab, it is crucial to be comfortable with the math calculations that are part of everyday work. This accessible introduction to common laboratory techniques focuses on the basics, helping even readers with good math skills to practice the most frequently encountered types of problems. Basic Laboratory Calculations for Biotechnology, Second Edition discusses very common laboratory problems, all applied to real situations. It explores multiple strategies for solving problems for a better understanding of the underlying math. Primarily organized around laboratory applications, the book begins with more general topics and moves into more specific biotechnology laboratory techniques at the end. This book features hundreds of practice problems, all with solutions and many with boxed, complete explanations; plus hundreds of "story problems" relating to real situations in the lab. Additional features include: Discusses common laboratory problems with all material applied to real situations Presents multiple strategies for solving problems help students to better understand the underlying math Provides hundreds of practice problems and their solutions Enables students to complete the material in a self-paced course structure with little teacher assistance Includes hundreds of "story problems"that relate to real situations encountered in the laboratory

Basic Laboratory Methods for Biotechnology, Third Edition is a versatile textbook that provides students with a solid foundation to pursue employment in the biotech industry and can later serve as a practical reference to ensure success at each stage in their career. The authors focus on basic principles and methods while skillfully including recent innovations and industry trends throughout. Fundamental laboratory skills are emphasized, and boxed content provides step by step laboratory method instructions for ease of reference at any point in the students' progress. Worked through examples and practice problems and solutions assist student comprehension. Coverage includes safety practices and instructions on using common laboratory instruments. Key Features: Provides a valuable reference for laboratory professionals at all stages of their careers. Focuses on basic principles and methods to provide students with the knowledge needed to begin a career in the Biotechnology industry. Describes fundamental laboratory skills. Includes laboratory scenario-based questions that require students to write or discuss their answers to ensure they have mastered the chapter content. Updates reflect recent innovations and regulatory requirements to ensure students stay up to date. Tables, a detailed glossary, practice problems and solutions, case studies and anecdotes provide students with the tools needed to master the content.

Presents critical discussion on various advancement on various extraction process including future trends. Provides elaborative description of food waste sources and challenges associated with it. Highlights potential of bioactive compounds in various industries. Quantitatively discusses existing as well as new technologies/methodologies. Includes a separate chapter on pertinent policies of various countries.

Although one of the oldest microbial technologies used in food processing, solid-state fermentation (SSF) had, until recently, fallen out of favor. However, based on a series of established mathematical models, new design concepts for SSF bioreactors and process control strategies have been proposed, allowing SSF technology to reach new levels. Solid State Fermentation for Foods and Beverages covers these new technologies and their application to food and beverage production. The book systematically describes the production of solid-state fermented food and beverage in terms of the history and development of SSF technology and SSF foods, bio-reactor design, fermentation process, various substrate origins and sustainable development. It emphasizes Oriental traditional foods produced by SSF such as sufu, vinegar, soy sauce, Chinese distilled spirit, and rice wine. The authors address such engineering issues as mass and heat transfer and energy equation calculation of solid-state fermentation, dynamic modeling of solid-state fermentation, and process control of solid-state fermentation. Covering the latest developments and achievements in the field of SSF, the book provides a detailed introduction to various solid-state fermented foods and beverages, including product category, characteristics, functionalities, safety issues, and consumer perception. It explores real advantages of SSF processes and how their application at real scale for high quality production that is more and less costly.

Microbial Cell Factories is a conceptual, reference-based source including chapters covering microbial cell factories for industrial developments, microbial biotechnology, sustainable environmental solutions, agriculture practices, microorganisms in food processing, metabolites as next generation food additives/food processing, and microbial cell factories in alternative energy fuel generation. The book highlights trends and developments in the field of microbial products, written by an international team of leading academic and research scholars. Key Selling Features: Highlights trends and developments in microbial biotechnology Systematically reviews microbial cell factories Explores the potential of microbial cell derived industrial production Synthesizes information on environmental and agricultural uses of microbial biotechnology Contributions from an international team of leading scholars

Adenoviruses are double stranded DNA viruses that have been used to study the process of DNA replication. Studies of the mode of action of adenovirally produced tumors in rodents led to the discovery of tumour supressor genes. The adenoviral vector is now the most used vector in clinical gene therapy especially for some kinds of cancers. The chapters in this book focus on the most up-to-date developments in the therapeutic applications of adenoviruses. The intended audience is individuals in the Life Sciences interested in therapeutic applications of adenoviruses. This book reviews the life history and immune responses to adenoviruses and summarizes various therapies implemented with the use of adenoviruses.

Viral Nanotechnology presents an up-to-date overview of the rapidly developing field of viral nanotechnology in the areas of immunology, virology, microbiology, chemistry, physics, and mathematical modeling. Its chapters are by leading researchers and practitioners, making it both a comprehensive and indispensable resource for study and research. The field of viral nanotechnology is new and quickly expanding due to increasing demand of the applications already developed. The editors identify viral nanotechnology as a significant science that concerns itself with how to use the molecular modules that the distinctly different science of molecular engineering only constructs. The current potential applications of viral technology are manifold, with opportunities to revolutionize practices in photonics, catalysis, electronics, energy, biomedicine, health care, and public health. This book emphasizes using viral nanotechnology to improve health. A special emphasis is placed upon using viral nanotechnology for developing vaccines. In addition, it documents viral nanotechnology's use as a powerful tool for developing drugs and genetic therapies. There is also great potential in its use as a means for diagnostics, including the development of diagnostic reagents and novel imaging technologies for detecting disease and infectious agents. Viral nanotechnology's rapid and exciting growth is due to the need for new tools in the prevention, diagnosis, and treatment of disease. The contributors to this volume approach each chapter with the hope that their research and practices will contribute to an improvement in health and life on an unprecedented scale in human history.

This comprehensive book focuses on multimodality imaging technology, including overviews of the instruments and methods followed by practical case studies that highlight use in the detection and treatment of cardiovascular diseases. Chapters cover PET-CT, SPECT-CT, SPECT-MRI, PET-MRI, PET-optical imaging, SPECT-optical imaging, photoacoustic Imaging, and hybrid intravascular imaging. It also addresses the important issues of multimodality imaging probes and image quantification. Readers from radiology and cardiology as well as medical imaging and biomedical engineering will learn essentials of the field. They will be shown how the field has advanced quantitative analysis of molecularly targeted imaging through improvements in the reliability and reproducibility of imaging data. Moreover, they will be presented with quantification algorithms and case illustrations, including coverage of such topics such as multimodality image fusion and kinetic modeling. Yi-Hwa Liu, PhD is Senior Research Scientist in Cardiovascular Medicine at Yale University School of Medicine and Technical Director of Nuclear Cardiology at Yale New Haven Hospital. He is also an Associate Professor (Adjunct) of Biomedical Imaging and Radiological Sciences at National Yang-Ming University, Taipei, Taiwan, and Professor (Adjunct) of Biomedical Engineering at Chung Yuan Christian University, Taoyuan, Taiwan. He is an elected senior member of Institute of Electrical and Electronic Engineers (IEEE) and a full member of Sigma Xi of The Scientific Research Society of North America. Albert J. Sinusas, M.D., FACC, FAHA is Professor of Medicine (Section of Cardiovascular Medicine) and Radiology and Biomedical Imaging, at Yale University School of Medicine, and Director of the Yale Translational Research Imaging Center (Y-TRIC), and Director of Advanced Cardiovascular Imaging at Yale New Haven Hospital. He is a recipient of the Society of Nuclear Medicine's Hermann Blumgart Award.

The global warming problem is becoming critical year by year, causing climate disaster all over the world, where it has been believed that the CO2 gas emitted from the factories and the burning of fossil fuels may be one of the reasons of global warming. Moreover, the global stock of fossil fuels is limited, and may run out soon within several tens of years. Although wind, geo-thermal, and tide energies have been considered as clean energy sources, those depend on the land or sea locations and subject to the climate change. Biofuel and biochemical production from renewable bio-resources has thus been paid recent attention from environmental protection and energy production points of view, where the current chemical and energy producing plants can be also utilized with slight modification. The so-called 1st generation biofuels have been produced from corn starch and sugarcane in particular in USA and Brazil. However, this causes the problem of the so-called "food and energy issues" as the production scale increases. The 2nd generation biofuel production from lingo-cellulosic biomass or wastes has thus been paid recent attention. However, it requires energy intensive pretreatment for the degradation of lingo-cellulosic biomass, and the fermentation is slow due to low growth rate, and thus the productivity of biofuels and bio-chemicals is low. The 3rd generation biofuel production from photosynthetic organisms such as cyanobacteria and algae has been also paid attention, because such organisms can grow with only sun light and CO2 in the air, but the cell growth rate and thus the productivity of the fuels is significantly low. The main part or core of such production processes is the fermentation by micro-organisms. In particular, it is critical to properly understand the cell metabolism followed by the efficient metabolic engineering. The book gives comprehensive explanation of the cell metabolism and the metabolic regulation mechanisms of a variety of micro-organisms. Then the efficient metabolic engineering approaches are explained to properly design the microbial cell factories for the efficient cell growth and biofuel and biochemical production.

This book is dedicated to the field of conductive polymers, focusing on electrical interactions with biological systems. It addresses the use of conductive polymers as the conducting interface for electrical communications with the biological system, both in vitro and in vivo. It provides an overview on the chemistry and physics of conductive polymers, their useful characteristics as well as limitations, and technologies that apply conductive polymers for medical purposes. This groundbreaking resource addresses cytotoxicity and tissue compatibility of conductive polymers, the basics on electromagnetic fields, and commonly used experimental methods. Readers will also learn how cells are cultured in vitro with conductive polymers, and how conductive polymers and living tissues interact electrically. Throughout the contents, chapter authors emphasize the importance of conductive polymers in biomedical engineering and their potential applications in medicine.

The book provides an insight into the advantages and limitations of the use of fractals in biomedical data. It begins with a brief introduction to the concept of fractals and other associated measures and describes applications for biomedical signals and images. Properties of biological data in relations to fractals and entropy, and the association with health and ageing are also covered. The book provides a detailed description of new techniques on physiological signals and images based on the fractal and chaos theory. The aim of this book is to serve as a comprehensive guide for researchers and readers interested in biomedical signal and image processing and feature extraction for disease risk analyses and rehabilitation applications. While it provides the mathematical rigor for those readers interested in such details, it also describes the topic intuitively such that it is suitable for audience who are interested in applying the methods to healthcare and clinical applications. The book is the outcome of years of research by the authors and is comprehensive and includes other reported outcomes.

With focus on the practical use of modern biotechnology for environmental sustainability, this book provides a thoughtful overview of molecular aspects of environmental studies to create a new awareness of fundamental biological processes and sustainable ecological concerns. It covers the latest research by prominent scientists in modern biology and delineates recent and prospective applications in the sub-areas of environmental biotechnology with special focus on the biodegradation of toxic pollutants, bioremediation of contaminated environments, and bioconversion of organic wastes toward a green economy and sustainable future.