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Current Developments in Biotechnology and Bioengineering: Production, Isolation and Purification of Industrial Products provides extensive coverage of new developments, state-of-the-art technologies, and potential future trends, focusing on industrial biotechnology and bioengineering practices for the production of industrial products, such as enzymes, organic acids, biopolymers, and biosurfactants, and the processes for isolating and purifying them from a production medium. During the last few years, the tools of molecular biology and genetic and metabolic engineering have rendered tremendous improvements in the production of industrial products by fermentation. Structured by industrial product classifications, this book provides an overview of the current practice, status, and future potential for the production of these agents, along with reviews of the industrial scenario relating to their production.
Current Developments in Biotechnology and Bioengineering: Solid Waste Management provides extensive coverage of new developments, state-of-the-art technologies, and potential future trends, reviewing the latest innovative developments in environmental biotechnology and bioengineering as they pertain to solid wastes, also revealing current research priority areas in solid waste treatment and management. The fate of solid wastes can be divided into three major areas, recycling, energy recovery, and safe disposal. From this foundation, the book covers such key areas as biotechnological production of value added products from solid waste, bioenergy production from various organic solid wastes, and biotechnological solutions for safe, environmentally-friendly treatment and disposal. The state of the art situation, potential advantages, and limitations are discussed, along with proposed strategies on how to overcome limitations.
Current Developments in Biotechnology and Bioengineering: Biological Treatment of Industrial Effluents provides extensive coverage of new developments, state-of-the-art technologies, and potential future trends in data-based scientific knowledge and advanced information on the role and application of environmental biotechnology and engineering in the treatment of industrial effluents. These treatment processes have been broadly classified under aerobic and anaerobic processes which determines the scope and level of pollutant removal. Chapters in this volume review the most recent developments and perspectives at different environmental cleanup operation scales.
Current Developments in Biotechnology and Bioengineering: Food and Beverages Industry provides extensive coverage of new developments, state-of-the-art technologies, and potential future trends compiled from the latest ideas across the entire arena of biotechnology and bioengineering. This volume reviews current developments in the application of food biotechnology and engineering for food and beverage production. As there have been significant advances in the areas of food fermentation, processing, and beverage production, this title highlights the advances in specific transformation processes, including those used for alcoholic beverage and fermented food production. Taking a food process and engineering point-of-view, the book also aims to select important bioengineering principles, highlighting how they can be quantitatively applied in the food and beverages industry.
Current Developments in Biotechnology and Bioengineering: Functional Genomics and Metabolic Engineering provides extensive coverage of new developments, state-of-the-art technologies, and potential future trends in the field, compiling the latest ideas from across the entire arena of biotechnology and bioengineering. This volume provides data-based scientific knowledge and state-of-art information on functional genomics and metabolic engineering. It covers the core subjects of functional genomics, such as epigenomics, metagenomics, genomics of extremophiles, genomics studies in nutrient transport, genomics of miRNA, and genomics of pathogenesis. An overview of metabolic engineering theories and approaches is supported with specific important examples of secondary metabolites, including Streptomyces, pentose utilization in E. coli, bacterial ethanol fermentation, yeast mediated benzaldehyde biotransformation, carotenoid production, acetic acid production by E. coli, and NADH regeneration.
Current Developments in Biotechnology and Bioengineering: Foundations of Biotechnology and Bioengineering is a package of nine books that compile the latest ideas from across the entire arena of biotechnology and bioengineering. This volume focuses on the underlying principles of biochemistry, microbiology, fermentation technology, and chemical engineering as interdisciplinary themes, constructing the foundation of biotechnology and bioengineering.
Adverse Effects of Engineered Nanoparticles: A Disease-Oriented Approach provides a systematic evaluation of representative engineered nanomaterial (ENM) of high volume production and of high economic importance. Each class of nanomaterials discussed includes information on what scientists, industry, regulatory agencies and the general public need to know about nanosafety. This book, written by leading international experts in nanotoxicology and nanmoedicine, gives a comprehensive view of the health impact of ENM, focusing on their potential adverse effects in exposed workers, consumers and patients. The beneficial applications, both diagnostic and therapeutic, of ENM are also highlighted. This book fills an important need in terms of bridging the gap between experimental findings and human exposure to ENM, and the clinical and pathological consequences of such exposure in the human population.
Biotechnology has impacted the textiles industry through the development of more efficient and environmentally friendly manufacturing processes, as well as enabling the design of improved textile materials. This book will provide a thorough overview of current and future focuses of biotechnology in the fibre and textile industry. Part one of the book opens with a review of technologies involved in textile biotechnology. Chapters explore the design and engineering of novel enzymes for textile applications and developments in processes and equipment for enzymatic textile treatments. Part two investigates the modification of particular fibres through the use of biotechnology. Key topics include the treatment of wool and silk fibres and the enzymatic treatment versus conventional processing of cotton. With expert contributions from leaders in their fields, Advances in textile biotechnology is a comprehensive guide for those in the textile and fibre industry, as well as experts in the biology, chemical and environmental engineering industries.
Cardiovascular disease is one of the leading causes of death in the world today. Thanks to major advances in circulatory biomaterials and medical devices over the past few decades, many complications of this prevalent disease can be managed with great success for prolonged periods. Biomaterials and devices for the circulatory system reviews the latest developments in this important field and how they can be used to improve the success and safety in this industry. Part one discusses physiological responses to biomaterials with chapters on tissue response, blood interface and biocompatibility. Part two then reviews clinical applications including developments in valve technology, percutaneous valve replacement, bypass technologies and cardiovascular stents. Part three covers future developments in the field with topics such as nanomedicine, cardiac restoration therapy, biosensor technology in the treatment of cardiovascular disease and vascular tissue engineering. With its distinguished editors and international team of contributors Biomaterials and devices for the circulatory system is a vital reference for those concerned with bioengineering, medical devices and clinicians within this critical field.
Biomaterials and medical devices must be rigorously tested in the laboratory before they can be implanted. Testing requires the right analytical techniques. Characterization of biomaterials reviews the latest methods for analyzing the structure, properties and behaviour of biomaterials. Beginning with an introduction to microscopy techniques for analyzing the phase nature and morphology of biomaterials, Characterization of biomaterials goes on to discuss scattering techniques for structural analysis, quantitative assays for measuring cell adhesion, motility and differentiation, and the evaluation of cell infiltration and tissue formation using bioreactors. Further topics considered include studying molecular-scale protein-surface interactions in biomaterials, analysis of the cellular genome and abnormalities, and the use of microarrays to measure cellular changes induced by biomaterials. Finally, the book concludes by outlining standards and methods for assessing the safety and biocompatibility of biomaterials. With its distinguished editors and international team of expert contributors, Characterization of biomaterials is an authoritative reference tool for all those involved in the development, production and application of biomaterials.
Novel injectable materials for non-invasive surgical procedures are becoming increasingly popular. An advantage of these materials include easy deliverability into the body, however the suitability of their mechanical properties must also be carefully considered. Injectable biomaterials covers the materials, properties and biomedical applications of injectable materials, as well as novel developments in the technology. Part one focuses on materials and properties, with chapters covering the design of injectable biomaterials as well as their rheological properties and the mechanical properties of injectable polymers and composites. Part two covers the clinical applications of injectable biomaterials, including chapters on drug delivery, tissue engineering and orthopaedic applications as well as injectable materials for gene delivery systems. In part three, existing and developing technologies are discussed. Chapters in this part cover such topics as environmentally responsive biomaterials, injectable nanotechnology, injectable biodegradable materials and biocompatibility. There are also chapters focusing on troubleshooting and potential future applications of injectable biomaterials. With its distinguished editor and international team of contributors, Injectable biomaterials is a standard reference for materials scientists and researchers working in the biomaterials industry, as well as those with an academic interest in the subject. It will also be beneficial to clinicians.
The surface modification of biomaterials plays a significant role in determining the outcome of biological-material interactions. With the appropriate modification a material's surface can be tailored to improve biocompatibility, adhesion and cell interactions. Consequently surface modification is vital in the development and design of new biomaterials and medical devices. Surface modification of biomaterials reviews both established surface modifications and those still in the early stages of research and discusses how they can be used to optimise biological interactions and enhance clinical performance. Part one begins with chapters looking at various types and techniques of surface modification including plasma polymerisation, covalent binding of poly (ethylene glycol) (PEG), heparinisation, peptide functionalisation and calcium phosphate deposition before going on to examine metal surface oxidation and biomaterial surface topography to control cellular response with particular reference to technologies, cell behaviour and biomedical applications. Part two studies the analytical techniques and applications of surface modification with chapters on analysing biomaterial surface chemistry, surface structure, morphology and topography before moving onto discuss modifying biomaterial surfaces to optimise interactions with blood, control infection, optimise interactions with soft tissues, repair and regenerate nerve cells, control stem cell growth and differentiation and to optimise interactions with bone. The distinguished editor and international team of contributors to Surface modification of biomaterials have produced a unique overview and detailed chapters on a range of surface modification techniques which will provide an excellent resource for biomaterials researchers and scientists and engineers concerned with improving the properties of biomaterials. It will also be beneficial for academics researching surface modification.
Mesenchymal Stromal Cells: Translational Pathways to Clinical Adoption provides the latest information on the necessary steps for successful production of stem cells for a clinical trial. Written by professionals with hands-on experience in bringing MSC therapies to the clinic, and building on the biology and mechanisms of action, this unique book covers the development and production of clinical-grade products that are suitable for use in humans. From design of a cell production facility, to obtaining regulatory approval and reimbursement issues, it is a useful guide for researchers and administrators across biomedical research.
New and Future Developments in Microbial Biotechnology and Bioengineering: Aspergillus System Properties and Applications provides information on emerging issues related to recent advancements in aspergillus research and its applications in bioprocess technology, chemical engineering, genome biology, molecular taxonomy, secondary and metabolite production, industrial process and biofuels/bioenergy research, and alternative fuel development. The book covers the various novel enzymes secreted by these fungi and their specific use in the food, textile, pulp and paper, biocellulosic ethanol production, and other industries. The book describes research and experimentation on aspergillus activity and directly connects them to their use in bioprocess technology, chemical engineering, bioremediation process, secondary metabolite production, pharmaceutical processes, protein production, industrial process, biofuels/bioenergy research, and alternative fuel development. Readers will find this book to be an indispensable resource for biotechnologists, biochemical engineers, biochemists, microbiologists, bioinformatics researchers, and other biologists who are interested in learning about the potential applications of these fungi.
New and Future Developments in Microbial Biotechnology and Bioengineering: Microbial Cellulase System Properties and Applications covers the biochemistry of cellulase system, its mechanisms of action, and its industrial applications. Research has shed new light on the mechanisms of microbial cellulase production and has led to the development of technologies for production and applications of cellulose degrading enzymes. The biological aspects of processing of cellulosic biomass have become the crux of future research involving cellulases and cellulolytic microorganisms, as they are being commercially produced by several industries globally and are widely being used in food, animal feed, fermentation, agriculture, pulp and paper, and textile applications. The book discusses modern biotechnology tools, especially in the area of microbial genetics, novel enzymes, and new enzyme and the applications in various industries. As a professional reference, this new book is useful to all researchers working with microbial cellulase system, both academic institutions and industry-based research bodies, as well as to teachers, graduate, and postgraduate students with information on continuous developments in microbial cellulase system. The book provides an indispensable reference source for chemists, biochemical engineers/bioengineers, biochemists, biotechnologists and researchers who want to know about the unique properties of this microbe and explore its future applications.
Genomics in Aquaculture is a concise, must-have reference that describes current advances within the field of genomics and their applications to aquaculture. Written in an accessible manner for anyone-non-specialists to experts alike-this book provides in-depth coverage of genomics spanning from genome sequencing, to transcriptomics and proteomics. It provides, for ease of learning, examples from key species most relevant to current intensive aquaculture practice. Its coverage of minority species that have a specific biological interest (e.g., Pleuronectiformes) makes this book useful for countries that are developing such species. It is a robust, practical resource that covers foundational, functional, and applied aspects of genomics in aquaculture, presenting the most current information in a field of research that is rapidly growing.
Marine Enzymes Biotechnology: Production and Industrial Applications, Part I, Production of Enzymes provides a huge treasure trove of information on marine organisms. Nowadays, marine organisms are good candidates for enzymes production and have been recognized as a rich source of biological molecules that are of potential interest to various industries. Marine enzymes such as amylases, carboxymethylcellulases, proteases, chitinases, keratinases, xylanases, agarases, lipases, peroxidase and tyrosinases are widely used in the industry for the manufacture of pharmaceuticals, foods, beverages, and confectioneries, as well as in textile and leather processing, and in waste water treatment. The majority of the enzymes used in the industry are of microbial origin because microbial enzymes are relatively more stable than the corresponding enzymes derived from plants and animals.
Bacterial Nanocellulose: From Biotechnology to Bio-Economy presents an overview on the current and future applications of bacterial nanocellulose, perspectives on the ecology and economics of its production, and a brief historic overview of BNC related companies.
Smart Bandage Technology: Design and Application is a guide to the integration of sensors and electronic systems into bandages for the application of wound management. Davis provides a comprehensive guide to the design and development of functional material for wound management for engineers of all levels possessing core knowledge in chemistry, biochemistry, and materials science. Includes an introduction to the design of advanced wound care technologies for undergraduate engineers, as well as a coherent exploration of competing technologies suitable for postgraduate and postdoctoral researchers. Each section provides a high level overview of the concepts and techniques involved in developing smart bandages, including their manufacturing, operation, and implementation, and also exposes and explores the most recent approaches to wound care in more detail. This book incorporates contextual boxes to provide a greater degree of detail to examples given and also includes an extensive bibliography for those seeking to research further on the various topics discussed.
Platform Chemical Biorefinery: Future Green Chemistry provides information on three different aspects of platform chemical biorefinery. The book first presents a basic introduction to the industry beneficial for university students, then provides engineering details of existing or potential platform chemical biorefinery processes helpful to technical staff of biorefineries. Finally, the book presents a critical review of the entire platform chemical biorefinery process, including extensive global biorefinery practices and their potential environmental and market-related consequences. Platform chemicals are building blocks of different valuable chemicals. The book evaluates the possibility of renewable feedstock-based platform chemical production and the fundamental challenges associated with this objective. Thus, the book is a useful reference for both academic readers and industry technical workers. The book guides the research community working in the field of platform chemical biorefinery to develop new pathways and technologies in combination with their market value and desirability.
New Techniques for Studying Biomembranes describes some of the latest methods used to investigate the dynamic distribution of specific lipids in membranes and their effects on other membrane components. The contributors present important discoveries with respect to lipid analysis and lipid interactions with membrane proteins. Various methods, which have been used to study lipid bilayer structure and lipid organization in membranes, include both in vitro and in vivo membrane systems, and study membrane proteins in various membrane systems. Key Features: Reviews both in vivo and in vitro analytical technologies and methods for studying membrane structure and function Explores how lipid bilayers and membrane proteins interact Includes contributions from an international team of researchers actively studying membrane structure and function Identifies various diseases whose causes are related to membrane proteins Related Titles: Christopher R. Jacobs, Hayden Huang, and Ronald Y. Kwon. Introduction to Cell Mechanics and Mechanobiology (ISBN 978-0-8153-4425-4) Wendell Lim and Bruce Mayer. Cell Signaling: Principles and Mechanisms (ISBN 978-0-8153-4244-1) Stephen Rothman. Proteins Crossing Membranes: A Scientist's Memoir (978-0-3670-7449-4)
Calculations in Molecular Biology and Biotechnology, Third Edition, helps researchers utilizing molecular biology and biotechnology techniques-from student to professional-understand which type of calculation to use and why. Research in biotechnology and molecular biology requires a vast amount of calculations. Results of one data set become the basis of the next. An error of choosing the wrong type of equation can turn what would have been a successful research project or weeks of labor and research into a veritable house of cards. It could be how you calculated the medium in which you test your sample to calculating how long it takes a sample to grow to calculating the synthesis of multiple variables. In one easy to use reference, Stephenson reviews the mathematics and statistics related to the day-to-day functions of biotechnology and molecular biology labs, which is a sticking point for many students, technicians, and researchers. The book covers all of the basic mathematical and statistical needs for students and professionals, providing them with a useful tool for their work.
Nano- and Microfabrication for Industrial and Biomedical Applications, Second Edition, focuses on the industrial perspective on micro- and nanofabrication methods, including large-scale manufacturing, the transfer of concepts from lab to factory, process tolerance, yield, robustness, and cost. The book gives a history of miniaturization and micro- and nanofabrication, and surveys industrial fields of application, illustrating fabrication processes of relevant micro and nano devices. In this second edition, a new focus area is nanoengineering as an important driver for the rise of novel applications by integrating bio-nanofabrication into microsystems. In addition, new material covers lithographic mould fabrication for soft-lithography, nanolithography techniques, corner lithography, advances in nanosensing, and the developing field of advanced functional materials. Luttge also explores the view that micro- and nanofabrication will be the key driver for a "tech-revolution" in biology and medical research that includes a new case study that covers the developing organ-on-chip concept.
Oxidative Stress and Biomaterials provides readers with the latest information on biomaterials and the oxidative stress that can pose an especially troubling challenge to their biocompatibility, especially given the fact that, at the cellular level, the tissue environment is a harsh landscape of precipitating proteins, infiltrating leukocytes, released oxidants, and fluctuations of pH which, even with the slightest shift in stasis, can induce a perpetual state of chronic inflammation. No material is 100% non-inflammatory, non-toxic, non-teratogenic, non-carcinogenic, non-thrombogenic, and non-immunogenic in all biological settings and situations. In this embattled terrain, the most we can hope for from the biomaterials we design is a type of "meso-compatibility," a material which can remain functional and benign for as long as required without succumbing to this cellular onslaught and inducing a local inflammatory reaction.
Tissue Engineering Made Easy provides concise, easy to understand, up-to-date information about the most important topics in tissue engineering. These include background and basic principles, clinical applications for a variety of organs (skin, nerves, eye, heart, lungs and bones), and the future of the field. The descriptions and explanations of each topic are such that those who have not had any exposure to the principles and practice of tissue engineering will be able to understand them, and the volume will serve as a source for self-teaching to get readers to a point where they can effectively engage with active researchers.
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