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Ophthalmic Product Development - From Bench to Bedside (Hardcover, 1st ed. 2021)
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Ophthalmic Product Development - From Bench to Bedside (Hardcover, 1st ed. 2021)
Series: AAPS Advances in the Pharmaceutical Sciences Series, 37
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This is a comprehensive textbook addressing the unique aspects of
drug development for ophthalmic use. Beginning with a perspective
on anatomy and physiology of the eye, the book provides a critical
appraisal of principles that underlie ocular drug product
development. The coverage encompasses topical and intraocular
formulations, small molecules and biologics (including protein and
gene therapies), conventional formulations (including solutions,
suspensions, and emulsions), novel formulations (including
nanoparticles, microparticles, and hydrogels), devices, and
specialty products. Critical elements such as pharmacokinetics,
influence of formulation technologies and ingredients, as well as
impact of disease conditions on products development are addressed.
Products intended for both the front and the back of the eye are
discussed with an eye towards future advances.
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