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Advances in DNA Sequence-Specific Agents, Volume 2 (Hardcover, UK ed.)
Loot Price: R1,890
Discovery Miles 18 900
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Advances in DNA Sequence-Specific Agents, Volume 2 (Hardcover, UK ed.)
Series: Advances in DNA Sequence - Specific Agents
Expected to ship within 12 - 17 working days
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DNA sequence specificity is a sub-specialty in the general area of
molecular recognition. This area includes macromolecular-molecular
interactions (e.g., protein-DNA), oligomer-DNA interacitons (e.g.,
triple strands), and ligand-DNA interactions (e.g., drug-DNA). It
is this latter group of DNA sequence specificity interactions that
is the subject of Volumes 1 and 2 of "Advances in DNA Sequence
Specific Agents." As was the case for Volume 1, Part A also covers
methodology, but in Volume 2 we include calorimetric titrations,
molecular modeling, X-ray crystallographic and NMR structural
studies, and transcriptional assays. Part B also follows the same
format as Volume 1 and describes the sequence specificities and
covalent and noncovalent interactions of small ligands with
DNA.
This volume is aimed in general at scientists who have an interest
in deciphering the molecular mechanisms for sequence recognition of
DNA. The methods have general applicability to small molecules as
well as oligomers and proteins, while the examples provide general
principles involved in sequence recognition.
General
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