Deficiencies in any of the defense mechanisms of the host can lead
to severe microbial infections; these are of clinical relevance.
Broad up-to-date knowledge in this field allows identification of
many unspecific as well as highly specific defense reactions
involved in the struggle against infectious diseases. On the other
hand, protective structures on the microbial cell surfaces have
been adapted and improve the counterpart's chances of survival. In
particular, it has been considered that the great diversity of the
bacterial envelopes not only determines the anatomical location of
the tissue injury but also induces activation of distinct parts of
the complex defense system. The specific defense mechanism, whose
most prominent constituent is provided by the antibo
General
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