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Ethnicity and Syndrome X (Hardcover)
Loot Price: R3,532
Discovery Miles 35 320
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Ethnicity and Syndrome X (Hardcover)
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The syndrome X or metabolic syndrome may be defined as a
constellation of several interrelated risk factors of metabolic
origin which includes centrally distributed obesity, decreased high
density lipoprotein cholesterol, elevated triglycerides, elevated
blood pressure and hyperglycemia. Persons with syndrome X are at
twice the risk of developing cardiovascular disease, and are at
about five-fold the risk of type 2 diabetes mellitus as compare to
persons with this syndrome. There are considerable evidences of
important ethnic differences in the prevalence of syndrome X, its
components and sequelae. The prevalence varied between ethnic
groups even within the same geographical location. Apart from
multifactorial (genetic vs. environmental) nature, there are
intriguing metabolic and anthropometric differences found across
different ethnic groups. The estimates vary by ethnicity, for
instance, high prevalence in nonaEuropean groups such as Black
AfricanaCaribbeans, Hispanics, indigenous populations of North
America, South Asians, and the Western Pacific Region and lower
prevalence in Chinese populations, and EuropeanaWhite. Public
health strategies that are well known to be important for chronic
disease prevention in general can substantially reduce the
prevalence of syndrome X. Population-specific studies will be
important in identifying subgroups for which syndrome X is a health
issue and for which disease management strategies are needed.
Simultaneously, studies to identify different biomarkers associated
with syndrome X that are linked with the development of specific
chronic diseases, such as CVD and diabetes, will significantly
enhance the early detection of these diseases. Existing preventions
strategies, if implemented in population subgroups at highest risk,
may have a substantial effect on reducing these trends. The
prevalence of syndrome X increases with advancing age suggests that
the efforts to increase awareness of prevention strategies must
begin early. Intensive treatment and effective targeting efforts
would help in avoiding future sequelae of syndrome X across
different ethnicity. This book will be an assemblage of
similarities and differences in the risk of syndrome X and related
disorders among different ethnic groups worldwide, and reviews
potential mechanisms for ethnic differences. It would certain help
in translational research for early intervention and better
prevention of syndrome X and its associated public health burden
worldwide.
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