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Books > Medicine > Clinical & internal medicine > Cardiovascular medicine
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Myocardial Ischemia and Preconditioning (Paperback, Softcover reprint of the original 1st ed. 2003)
Loot Price: R5,781
Discovery Miles 57 810
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Myocardial Ischemia and Preconditioning (Paperback, Softcover reprint of the original 1st ed. 2003)
Series: Progress in Experimental Cardiology, 6
Expected to ship within 10 - 15 working days
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Current evidence suggests that the ischemic preconditioning
response is a multi-factorial process consisting of an initial
early trigger, an intermediate mediator, and an end effector. Each
of these steps in is now its own intense area of investigation. The
need to render the heart ischemic for a brief period to invoke the
preconditioning response is currently the major factor limiting
clinical application of this powerful cardioprotective strategy.
Recent research efforts have utilized brief exposures to
pharmacological agents, in lieu of a brief preconditioning
ischemia, to trigger/mimic the ischemic preconditioning-induced
response. The World Heart Congress held in Winnipeg in July 2001
provided a forum for the presentation of new insights into the
basic mechanisms of ischemia and reperfusion injury, as well as
novel strategies to protect the heart from cell death, ventricular
arrhythmias, and contractile dysfunction. Many pioneers in the
fields of ischemia-reperfusion injury and preconditioning-induced
protection presented there and the chapters in this book represent
selected papers from these symposia.
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