Synthesis of Azetidines from Imines by Cycloaddition Reactions
presents several methodologies for the synthesis of azetidines from
imines by cycloaddition reactions. The azetidines, known as
important contribution of science to humanity, are important
organic compounds that have occupied a basic position in the
pharmaceutical chemistry for over a hundred years because of their
biological activities. They are the fundamental skeleton of several
antibiotics, probiotics and alkaloids. The synthesis of azetidines
is a constant challenge for medicinal chemists, hence this book
comprehensively describes azetidine ring synthesis. With this book,
readers will be able to quickly assess possible synthetic
approaches and evaluate whether preparation of a four-membered
nitrogen containing ring is reasonable.
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