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Books > Medicine > Other branches of medicine > Psychiatry
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Estrogen Effects in Psychiatric Disorders (Hardcover, 2005 ed.)
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Estrogen Effects in Psychiatric Disorders (Hardcover, 2005 ed.)
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The study of the effects of gonadal hormones in the brain focussed
mainly on reproductive actions for a long time. Meanwhile, however,
it is well known that gonadal hormones, in particular estrogens,
also have neuroprotective and psychoprotective properties. They
modulate many brain functions such as cognitive functions, pain
regulation, motor coordination, and epilepsy, as well as affective
and psychotic disorders, to name just a few. In fact, during the
past few years we have experienced a major change in our
understanding of the endocrinologic aspects of psychiatric
disorders. Endocrinologic irregularities in psychiatric patients
are no longer viewed as pure epiphenomena but rather discussed as
part of the pathomechanism of the disorders. How exactly estrogens
affect various disorders is a fascinating and intriguing aspect of
this emerging field of non-reproductive brain actions of gonadal
hormones. Among the estrogens, especially estradiol appears to play
an important and multimodal role in the brain. Which of estradiol s
many membrane, intracellular, and genomic actions matters most in
psychiatric disorders, remains to be discovered. The aim of this
volume is to summarize the role estrogens play in major psychiatric
disorders, such as schizophrenia, depression, and dementia, and to
provide a state-of-the-art overview of current knowledge, but also
of questions that are still open. It is intended to be a resource
for clinicians and readers who are interested in contemporary
research developments in this field.
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