The means by which proteins and RNAs are exchanged between
cytoplasm and nucleus have interested cell biologists for many
years, and the field has seen a number of exciting recent advances.
Much has been learned about the intricate architecture of the
nuclear pore-complex, the mechanisms by which transport substrates
are sorted, and the supply of energy for exchange processes. This
book attempts a general review of the growing body of knowledge.
However, the authors challenge the presumptions implicit in some
interpretations of the evidence, re-examining the concept of
"transport" within cells, and suggesting that lessons learned from
nucleocytoplasmic transport studies can elucidate wider aspects of
cell biology.
General
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