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Coronary flow reserve - measurement and application: Focus on transthoracic Doppler echocardiography (Paperback, Softcover reprint of the original 1st ed. 2002)
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Coronary flow reserve - measurement and application: Focus on transthoracic Doppler echocardiography (Paperback, Softcover reprint of the original 1st ed. 2002)
Series: Basic Science for the Cardiologist, 13
Expected to ship within 10 - 15 working days
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Coronary flow reserve is an important functional parameter to
understand the pathophysiology of coronary circulation. Coronary
flow reserve measurement is used to assess epicardial coronary
stenoses or to examine the integrity of microvascular circulation.
An appreciation of coronary physiology is an integral part of
clinical decision-making for cardiologists treating patients with
coronary artery disease. The pioneering research efforts of Dr
Lance Gould, who explored the relationship between the anatomic
severity of a stenosis and its flow resistance (59;60) , have been
transferred to clinical practice (94; 194). In the absence of
stenosis in epicardial coronary artery, the coronary flow reserve
may be decreased when coronary microvascular circulation is
compromised by arterial hypertension with or without left
ventricular hypertrophy, diabetes mellitus, hypercholesterolemia,
or other diseases. Several techniques have been established for
measuring coronary flow reserve. However, these techniques are
either invasive (intracoronary Doppler flow wire), highly expensive
and scarcely available (Positron Emission Tomography - PET) or
semi-invasive and causing patient discomfort (transesophageal
Doppler echocardiography), thus their clinical use is limited.
Because of the clinical importance of coronary flow reserve there
is a need for a simple, noninvasive, repeatable and inexpensive
tool capable of this functional evaluation. This monograph focuses
on the assessment of coronary flow reserve using transthoracic
Doppler echocardiography - the technique fulfilling the
above-mentioned criteria. Transthoracic Doppler echocardiography
has become a popular tool evolving from a research to diagnostic
technique applied in everyday practice.
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