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Membrane Transporters - Methods and Protocols (Paperback, Softcover reprint of hardcover 1st ed. 2003)
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Membrane Transporters - Methods and Protocols (Paperback, Softcover reprint of hardcover 1st ed. 2003)
Series: Methods in Molecular Biology, 227
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Studies of membrane transporters have had great impact on our und-
standing human diseases and the design of effective drugs. About
30% of current clinically marketed drugs are targeting membrane
transporters or channels. Membrane Transporters: Methods and
Protocols provides various practical methodologies for the ongoing
research on membrane transporters. To provide readers the most
up-to-date information, several emerging fields and methodologies
are embraced in this book, including pharmacogenomics,
bioin-formatics, and microarray technology. Pharmacogenomics
studies of membrane transporters are useful in drug discovery and
in predicting drug responses in the clinic. In this volume, the
current status of pharma- genomics studies of transporters is
reviewed and research methodologies in this field are described.
Transporter classification is important in studying the structure
and function of membrane transporters and has thus triggered
intensive interest in recent years. Membrane Transporters: Methods
and Protocols provides a systematic classification of all
transmembrane transport proteins found in living org- isms on
Earth. This classification system will be helpful for further
studies on various aspects of membrane transporters, especially for
such large-scale gene expression studies as those employing
microarray technologies. Bioinformatics is frequently used in
transporter studies and has become indispensable for all kinds of
research methods. Commonly used bio- formatics methods, such as
databases and tools for sequence analysis and - tif studies, are
explained in order to facilitate membrane transporters research.
Because of heterogeneous sources and tremendous amounts of data,
data in- gration has become one of the most important issues in
transporter studies.
General
Imprint: |
HumanaPress
|
Country of origin: |
United States |
Series: |
Methods in Molecular Biology, 227 |
Release date: |
November 2010 |
First published: |
2003 |
Editors: |
Qing Yan
|
Dimensions: |
229 x 152 x 21mm (L x W x T) |
Format: |
Paperback
|
Pages: |
372 |
Edition: |
Softcover reprint of hardcover 1st ed. 2003 |
ISBN-13: |
978-1-61737-359-6 |
Categories: |
Books >
Science & Mathematics >
Biology, life sciences >
Cellular biology >
General
|
LSN: |
1-61737-359-1 |
Barcode: |
9781617373596 |
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