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Introduction to Drug Designing & Development (Hardcover)
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Introduction to Drug Designing & Development (Hardcover)
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This book is useful to readers who are just beginning in the field
of drug design and development. It starts with an introduction and
some basic information about drugs. Pharmacokinetic and
pharmacodynamic aspects are covered in the initial chapters.
Systemic descriptions of pharmacokinetic parameters such as
absorption, distribution, metabolism, and excretion are explained
in simple and easy language. This book demonstrates detailed
concepts of lead molecules and their sources. In addition, drug
target classification, identification and validation strategies, as
well as the design and development of combinatorial libraries for
new lead generation are also covered. This book contains various
methodologies, such as structure-based drug designing, quantitative
structure activity relationship, pharmacophore modelling, and
docking studies for screening and designing the drug candidates.
This book will help in the identification and design of drugs that
could be potentially useful in deriving the candidate drugs, which
may have efficacy in animal models or cell cultures. Thus, the most
effective compounds could be employed based on the above results,
and will then be moved from preclinical studies to clinical trials.
The last couple of chapters describe dosage drug regulatory affairs
and recent advancements in healthcare. The aim of this book is to
provide comprehensive ideas about overall drug design and
development.
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