Once thought to be extremely rare, juvenile-onset schizophrenia
occurs in almost one-third of all persons with schizophrenia.
Clinically, adolescents tend to have different, usually poorer,
outcomes than adults with schizophrenia, and they respond
differently to treatments. Because their age precludes them from
functioning independently, adolescents are generally considered
more vulnerable, and they require age-appropriate psychosocial
interventions. From a scientific perspective, the fact that
adolescents appear to have a more severe form of the disease may
provide researchers with useful insights into its neurobiology.
Reflecting the substantial advances of the past decade,
"Juvenile-Onset Schizophrenia" brings together leading experts to
review state-of-the-art clinical practices and the latest
scientific knowledge regarding adolescent schizophrenia.
Contributors assess the developmental hypothesis of the disease,
examine the relationship between its onset of and neurobiological
changes during adolescence, and take into account genetic and other
risk factors. Also addressed are comparisons between
neurophysiology and structural neuroimaging in adults and
juveniles, psychological development during adolescence, early
symptoms of the disease, related psychotic disorders, the responses
of adolescents to antipsychotic medications, and the role of
psychotherapy and families in treating schizophrenia. In a
concluding essay, the editors review ethical and methodological
issues and discuss avenues for further research.
This comprehensive overview of the phenomenology, epidemiology,
pathology, and treatment of juvenile-onset schizophrenia will be
useful to clinicians, researchers, and students.
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